5DOW

Solution of the Variably-Twinned Structure of a Novel Calmodulin-Peptide Complex in a Novel Configuration

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000086	biological_process	G2/M transition of mitotic cell cycle
A	0000922	cellular_component	spindle pole
A	0002027	biological_process	regulation of heart rate
A	0005509	molecular_function	calcium ion binding
A	0005513	biological_process	detection of calcium ion
A	0005515	molecular_function	protein binding
A	0005576	cellular_component	extracellular region
A	0005634	cellular_component	nucleus
A	0005654	cellular_component	nucleoplasm
A	0005737	cellular_component	cytoplasm
A	0005813	cellular_component	centrosome
A	0005819	cellular_component	spindle
A	0005829	cellular_component	cytosol
A	0005856	cellular_component	cytoskeleton
A	0005876	cellular_component	spindle microtubule
A	0005886	cellular_component	plasma membrane
A	0007186	biological_process	G protein-coupled receptor signaling pathway
A	0008076	cellular_component	voltage-gated potassium channel complex
A	0010800	biological_process	positive regulation of peptidyl-threonine phosphorylation
A	0010801	biological_process	negative regulation of peptidyl-threonine phosphorylation
A	0010856	molecular_function	adenylate cyclase activator activity
A	0010880	biological_process	regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
A	0010881	biological_process	regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
A	0016020	cellular_component	membrane
A	0016240	biological_process	autophagosome membrane docking
A	0019855	molecular_function	calcium channel inhibitor activity
A	0019901	molecular_function	protein kinase binding
A	0021762	biological_process	substantia nigra development
A	0030017	cellular_component	sarcomere
A	0031432	molecular_function	titin binding
A	0031514	cellular_component	motile cilium
A	0031954	biological_process	positive regulation of protein autophosphorylation
A	0031982	cellular_component	vesicle
A	0032465	biological_process	regulation of cytokinesis
A	0032516	biological_process	positive regulation of phosphoprotein phosphatase activity
A	0032991	cellular_component	protein-containing complex
A	0034704	cellular_component	calcium channel complex
A	0035307	biological_process	positive regulation of protein dephosphorylation
A	0035458	biological_process	cellular response to interferon-beta
A	0043209	cellular_component	myelin sheath
A	0043539	molecular_function	protein serine/threonine kinase activator activity
A	0044305	cellular_component	calyx of Held
A	0044325	molecular_function	transmembrane transporter binding
A	0046427	biological_process	positive regulation of receptor signaling pathway via JAK-STAT
A	0046872	molecular_function	metal ion binding
A	0048306	molecular_function	calcium-dependent protein binding
A	0050848	biological_process	regulation of calcium-mediated signaling
A	0051343	biological_process	positive regulation of cyclic-nucleotide phosphodiesterase activity
A	0051592	biological_process	response to calcium ion
A	0055117	biological_process	regulation of cardiac muscle contraction
A	0060314	biological_process	regulation of ryanodine-sensitive calcium-release channel activity
A	0060315	biological_process	negative regulation of ryanodine-sensitive calcium-release channel activity
A	0060316	biological_process	positive regulation of ryanodine-sensitive calcium-release channel activity
A	0071346	biological_process	cellular response to type II interferon
A	0071902	biological_process	positive regulation of protein serine/threonine kinase activity
A	0072542	molecular_function	protein phosphatase activator activity
A	0097225	cellular_component	sperm midpiece
A	0098901	biological_process	regulation of cardiac muscle cell action potential
A	0099523	cellular_component	presynaptic cytosol
A	0140056	biological_process	organelle localization by membrane tethering
A	0140238	biological_process	presynaptic endocytosis
A	1901020	biological_process	negative regulation of calcium ion transmembrane transporter activity
A	1901842	biological_process	negative regulation of high voltage-gated calcium channel activity
A	1901844	biological_process	regulation of cell communication by electrical coupling involved in cardiac conduction
A	1902494	cellular_component	catalytic complex
A	1905913	biological_process	negative regulation of calcium ion export across plasma membrane
A	1990456	biological_process	mitochondrion-endoplasmic reticulum membrane tethering
C	0000086	biological_process	G2/M transition of mitotic cell cycle
C	0000922	cellular_component	spindle pole
C	0002027	biological_process	regulation of heart rate
C	0005509	molecular_function	calcium ion binding
C	0005513	biological_process	detection of calcium ion
C	0005515	molecular_function	protein binding
C	0005576	cellular_component	extracellular region
C	0005634	cellular_component	nucleus
C	0005654	cellular_component	nucleoplasm
C	0005737	cellular_component	cytoplasm
C	0005813	cellular_component	centrosome
C	0005819	cellular_component	spindle
C	0005829	cellular_component	cytosol
C	0005856	cellular_component	cytoskeleton
C	0005876	cellular_component	spindle microtubule
C	0005886	cellular_component	plasma membrane
C	0007186	biological_process	G protein-coupled receptor signaling pathway
C	0008076	cellular_component	voltage-gated potassium channel complex
C	0010800	biological_process	positive regulation of peptidyl-threonine phosphorylation
C	0010801	biological_process	negative regulation of peptidyl-threonine phosphorylation
C	0010856	molecular_function	adenylate cyclase activator activity
C	0010880	biological_process	regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
C	0010881	biological_process	regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
C	0016020	cellular_component	membrane
C	0016240	biological_process	autophagosome membrane docking
C	0019855	molecular_function	calcium channel inhibitor activity
C	0019901	molecular_function	protein kinase binding
C	0021762	biological_process	substantia nigra development
C	0030017	cellular_component	sarcomere
C	0031432	molecular_function	titin binding
C	0031514	cellular_component	motile cilium
C	0031954	biological_process	positive regulation of protein autophosphorylation
C	0031982	cellular_component	vesicle
C	0032465	biological_process	regulation of cytokinesis
C	0032516	biological_process	positive regulation of phosphoprotein phosphatase activity
C	0032991	cellular_component	protein-containing complex
C	0034704	cellular_component	calcium channel complex
C	0035307	biological_process	positive regulation of protein dephosphorylation
C	0035458	biological_process	cellular response to interferon-beta
C	0043209	cellular_component	myelin sheath
C	0043539	molecular_function	protein serine/threonine kinase activator activity
C	0044305	cellular_component	calyx of Held
C	0044325	molecular_function	transmembrane transporter binding
C	0046427	biological_process	positive regulation of receptor signaling pathway via JAK-STAT
C	0046872	molecular_function	metal ion binding
C	0048306	molecular_function	calcium-dependent protein binding
C	0050848	biological_process	regulation of calcium-mediated signaling
C	0051343	biological_process	positive regulation of cyclic-nucleotide phosphodiesterase activity
C	0051592	biological_process	response to calcium ion
C	0055117	biological_process	regulation of cardiac muscle contraction
C	0060314	biological_process	regulation of ryanodine-sensitive calcium-release channel activity
C	0060315	biological_process	negative regulation of ryanodine-sensitive calcium-release channel activity
C	0060316	biological_process	positive regulation of ryanodine-sensitive calcium-release channel activity
C	0071346	biological_process	cellular response to type II interferon
C	0071902	biological_process	positive regulation of protein serine/threonine kinase activity
C	0072542	molecular_function	protein phosphatase activator activity
C	0097225	cellular_component	sperm midpiece
C	0098901	biological_process	regulation of cardiac muscle cell action potential
C	0099523	cellular_component	presynaptic cytosol
C	0140056	biological_process	organelle localization by membrane tethering
C	0140238	biological_process	presynaptic endocytosis
C	1901020	biological_process	negative regulation of calcium ion transmembrane transporter activity
C	1901842	biological_process	negative regulation of high voltage-gated calcium channel activity
C	1901844	biological_process	regulation of cell communication by electrical coupling involved in cardiac conduction
C	1902494	cellular_component	catalytic complex
C	1905913	biological_process	negative regulation of calcium ion export across plasma membrane
C	1990456	biological_process	mitochondrion-endoplasmic reticulum membrane tethering
E	0000086	biological_process	G2/M transition of mitotic cell cycle
E	0000922	cellular_component	spindle pole
E	0002027	biological_process	regulation of heart rate
E	0005509	molecular_function	calcium ion binding
E	0005513	biological_process	detection of calcium ion
E	0005515	molecular_function	protein binding
E	0005576	cellular_component	extracellular region
E	0005634	cellular_component	nucleus
E	0005654	cellular_component	nucleoplasm
E	0005737	cellular_component	cytoplasm
E	0005813	cellular_component	centrosome
E	0005819	cellular_component	spindle
E	0005829	cellular_component	cytosol
E	0005856	cellular_component	cytoskeleton
E	0005876	cellular_component	spindle microtubule
E	0005886	cellular_component	plasma membrane
E	0007186	biological_process	G protein-coupled receptor signaling pathway
E	0008076	cellular_component	voltage-gated potassium channel complex
E	0010800	biological_process	positive regulation of peptidyl-threonine phosphorylation
E	0010801	biological_process	negative regulation of peptidyl-threonine phosphorylation
E	0010856	molecular_function	adenylate cyclase activator activity
E	0010880	biological_process	regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
E	0010881	biological_process	regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
E	0016020	cellular_component	membrane
E	0016240	biological_process	autophagosome membrane docking
E	0019855	molecular_function	calcium channel inhibitor activity
E	0019901	molecular_function	protein kinase binding
E	0021762	biological_process	substantia nigra development
E	0030017	cellular_component	sarcomere
E	0031432	molecular_function	titin binding
E	0031514	cellular_component	motile cilium
E	0031954	biological_process	positive regulation of protein autophosphorylation
E	0031982	cellular_component	vesicle
E	0032465	biological_process	regulation of cytokinesis
E	0032516	biological_process	positive regulation of phosphoprotein phosphatase activity
E	0032991	cellular_component	protein-containing complex
E	0034704	cellular_component	calcium channel complex
E	0035307	biological_process	positive regulation of protein dephosphorylation
E	0035458	biological_process	cellular response to interferon-beta
E	0043209	cellular_component	myelin sheath
E	0043539	molecular_function	protein serine/threonine kinase activator activity
E	0044305	cellular_component	calyx of Held
E	0044325	molecular_function	transmembrane transporter binding
E	0046427	biological_process	positive regulation of receptor signaling pathway via JAK-STAT
E	0046872	molecular_function	metal ion binding
E	0048306	molecular_function	calcium-dependent protein binding
E	0050848	biological_process	regulation of calcium-mediated signaling
E	0051343	biological_process	positive regulation of cyclic-nucleotide phosphodiesterase activity
E	0051592	biological_process	response to calcium ion
E	0055117	biological_process	regulation of cardiac muscle contraction
E	0060314	biological_process	regulation of ryanodine-sensitive calcium-release channel activity
E	0060315	biological_process	negative regulation of ryanodine-sensitive calcium-release channel activity
E	0060316	biological_process	positive regulation of ryanodine-sensitive calcium-release channel activity
E	0071346	biological_process	cellular response to type II interferon
E	0071902	biological_process	positive regulation of protein serine/threonine kinase activity
E	0072542	molecular_function	protein phosphatase activator activity
E	0097225	cellular_component	sperm midpiece
E	0098901	biological_process	regulation of cardiac muscle cell action potential
E	0099523	cellular_component	presynaptic cytosol
E	0140056	biological_process	organelle localization by membrane tethering
E	0140238	biological_process	presynaptic endocytosis
E	1901020	biological_process	negative regulation of calcium ion transmembrane transporter activity
E	1901842	biological_process	negative regulation of high voltage-gated calcium channel activity
E	1901844	biological_process	regulation of cell communication by electrical coupling involved in cardiac conduction
E	1902494	cellular_component	catalytic complex
E	1905913	biological_process	negative regulation of calcium ion export across plasma membrane
E	1990456	biological_process	mitochondrion-endoplasmic reticulum membrane tethering
G	0000086	biological_process	G2/M transition of mitotic cell cycle
G	0000922	cellular_component	spindle pole
G	0002027	biological_process	regulation of heart rate
G	0005509	molecular_function	calcium ion binding
G	0005513	biological_process	detection of calcium ion
G	0005515	molecular_function	protein binding
G	0005576	cellular_component	extracellular region
G	0005634	cellular_component	nucleus
G	0005654	cellular_component	nucleoplasm
G	0005737	cellular_component	cytoplasm
G	0005813	cellular_component	centrosome
G	0005819	cellular_component	spindle
G	0005829	cellular_component	cytosol
G	0005856	cellular_component	cytoskeleton
G	0005876	cellular_component	spindle microtubule
G	0005886	cellular_component	plasma membrane
G	0007186	biological_process	G protein-coupled receptor signaling pathway
G	0008076	cellular_component	voltage-gated potassium channel complex
G	0010800	biological_process	positive regulation of peptidyl-threonine phosphorylation
G	0010801	biological_process	negative regulation of peptidyl-threonine phosphorylation
G	0010856	molecular_function	adenylate cyclase activator activity
G	0010880	biological_process	regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
G	0010881	biological_process	regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
G	0016020	cellular_component	membrane
G	0016240	biological_process	autophagosome membrane docking
G	0019855	molecular_function	calcium channel inhibitor activity
G	0019901	molecular_function	protein kinase binding
G	0021762	biological_process	substantia nigra development
G	0030017	cellular_component	sarcomere
G	0031432	molecular_function	titin binding
G	0031514	cellular_component	motile cilium
G	0031954	biological_process	positive regulation of protein autophosphorylation
G	0031982	cellular_component	vesicle
G	0032465	biological_process	regulation of cytokinesis
G	0032516	biological_process	positive regulation of phosphoprotein phosphatase activity
G	0032991	cellular_component	protein-containing complex
G	0034704	cellular_component	calcium channel complex
G	0035307	biological_process	positive regulation of protein dephosphorylation
G	0035458	biological_process	cellular response to interferon-beta
G	0043209	cellular_component	myelin sheath
G	0043539	molecular_function	protein serine/threonine kinase activator activity
G	0044305	cellular_component	calyx of Held
G	0044325	molecular_function	transmembrane transporter binding
G	0046427	biological_process	positive regulation of receptor signaling pathway via JAK-STAT
G	0046872	molecular_function	metal ion binding
G	0048306	molecular_function	calcium-dependent protein binding
G	0050848	biological_process	regulation of calcium-mediated signaling
G	0051343	biological_process	positive regulation of cyclic-nucleotide phosphodiesterase activity
G	0051592	biological_process	response to calcium ion
G	0055117	biological_process	regulation of cardiac muscle contraction
G	0060314	biological_process	regulation of ryanodine-sensitive calcium-release channel activity
G	0060315	biological_process	negative regulation of ryanodine-sensitive calcium-release channel activity
G	0060316	biological_process	positive regulation of ryanodine-sensitive calcium-release channel activity
G	0071346	biological_process	cellular response to type II interferon
G	0071902	biological_process	positive regulation of protein serine/threonine kinase activity
G	0072542	molecular_function	protein phosphatase activator activity
G	0097225	cellular_component	sperm midpiece
G	0098901	biological_process	regulation of cardiac muscle cell action potential
G	0099523	cellular_component	presynaptic cytosol
G	0140056	biological_process	organelle localization by membrane tethering
G	0140238	biological_process	presynaptic endocytosis
G	1901020	biological_process	negative regulation of calcium ion transmembrane transporter activity
G	1901842	biological_process	negative regulation of high voltage-gated calcium channel activity
G	1901844	biological_process	regulation of cell communication by electrical coupling involved in cardiac conduction
G	1902494	cellular_component	catalytic complex
G	1905913	biological_process	negative regulation of calcium ion export across plasma membrane
G	1990456	biological_process	mitochondrion-endoplasmic reticulum membrane tethering

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	binding site for residue SO4 A 201

Chain	Residue
A	THR35
A	ARG38
A	HOH383
C	HOH432
G	HOH491
G	HOH529

---

site_id	AC2
Number of Residues	6
Details	binding site for residue CA A 202

Chain	Residue
A	TYR100
A	GLU105
A	HOH452
A	ASP94
A	ASP96
A	ASN98

---

site_id	AC3
Number of Residues	6
Details	binding site for residue CA A 203

Chain	Residue
A	ASP57
A	ASP59
A	ASN61
A	THR63
A	GLU68
A	HOH338

---

site_id	AC4
Number of Residues	6
Details	binding site for residue CA A 204

Chain	Residue
A	ASP21
A	ASP23
A	ASP25
A	THR27
A	GLU32
A	HOH390

---

site_id	AC5
Number of Residues	6
Details	binding site for residue CA A 205

Chain	Residue
A	ASP130
A	ASP132
A	ASP134
A	GLN136
A	GLU141
A	HOH328

---

site_id	AC6
Number of Residues	2
Details	binding site for residue CL A 206

Chain	Residue
A	GLU7
A	HOH501

---

site_id	AC7
Number of Residues	3
Details	binding site for residue NA A 207

Chain	Residue
A	GLU7
A	HOH501
A	HOH515

---

site_id	AC8
Number of Residues	6
Details	binding site for residue CA C 201

Chain	Residue
C	ASP94
C	ASP96
C	ASN98
C	TYR100
C	GLU105
C	HOH455

---

site_id	AC9
Number of Residues	6
Details	binding site for residue CA C 202

Chain	Residue
C	ASP130
C	ASP132
C	ASP134
C	GLN136
C	GLU141
C	HOH320

---

site_id	AD1
Number of Residues	7
Details	binding site for residue CA C 203

Chain	Residue
C	ASP57
C	ASP59
C	ASN61
C	THR63
C	GLU68
C	HOH309
C	HOH391

---

site_id	AD2
Number of Residues	6
Details	binding site for residue CA C 204

Chain	Residue
C	ASP21
C	ASP23
C	ASP25
C	THR27
C	GLU32
C	HOH363

---

site_id	AD3
Number of Residues	2
Details	binding site for residue CL C 205

Chain	Residue
A	HOH438
C	LYS95

---

site_id	AD4
Number of Residues	5
Details	binding site for residue CL C 206

Chain	Residue
C	THR45
C	GLU46
C	ASN61
C	HOH545
C	HOH556

---

site_id	AD5
Number of Residues	2
Details	binding site for residue CL C 207

Chain	Residue
C	ARG38
C	HOH419

---

site_id	AD6
Number of Residues	3
Details	binding site for residue NA C 208

Chain	Residue
C	ASP119
C	GLU120
C	ASP123

---

site_id	AD7
Number of Residues	2
Details	binding site for residue NA C 209

Chain	Residue
C	GLU83
E	HOH350

---

site_id	AD8
Number of Residues	4
Details	binding site for residue NA C 210

Chain	Residue
C	GLU140
C	VAL143
C	HOH340
G	GLU83

---

site_id	AD9
Number of Residues	6
Details	binding site for residue CA E 201

Chain	Residue
E	ASP57
E	ASP59
E	ASN61
E	THR63
E	GLU68
E	HOH354

---

site_id	AE1
Number of Residues	6
Details	binding site for residue CA E 202

Chain	Residue
E	ASP21
E	ASP23
E	ASP25
E	THR27
E	GLU32
E	HOH402

---

site_id	AE2
Number of Residues	6
Details	binding site for residue CA E 203

Chain	Residue
E	ASP94
E	ASP96
E	ASN98
E	TYR100
E	GLU105
E	HOH491

---

site_id	AE3
Number of Residues	6
Details	binding site for residue CA E 204

Chain	Residue
E	GLN136
E	GLU141
E	HOH349
E	ASP130
E	ASP132
E	ASP134

---

site_id	AE4
Number of Residues	6
Details	binding site for residue CL E 205

Chain	Residue
A	PRO67
A	GLU68
A	THR71
E	LYS14
E	HOH512
E	HOH566

---

site_id	AE5
Number of Residues	2
Details	binding site for residue CL E 206

Chain	Residue
E	LYS95
E	HOH342

---

site_id	AE6
Number of Residues	4
Details	binding site for residue CL E 207

Chain	Residue
E	THR6
E	GLU7
E	HOH388
E	HOH476

---

site_id	AE7
Number of Residues	4
Details	binding site for residue CL F 601

Chain	Residue
F	GLN575
F	GLY578
F	ILE580
F	GLN581

---

site_id	AE8
Number of Residues	3
Details	binding site for residue CL F 602

Chain	Residue
E	ILE86
F	ARG572
F	GLN575

---

site_id	AE9
Number of Residues	6
Details	binding site for residue SO4 G 201

Chain	Residue
E	HOH570
G	THR35
G	ARG38
G	HOH370
G	HOH380
G	HOH409

---

site_id	AF1
Number of Residues	6
Details	binding site for residue CA G 202

Chain	Residue
G	ASP57
G	ASP59
G	ASN61
G	THR63
G	GLU68
G	HOH440

---

site_id	AF2
Number of Residues	6
Details	binding site for residue CA G 203

Chain	Residue
G	ASP94
G	ASP96
G	ASN98
G	TYR100
G	GLU105
G	HOH456

---

site_id	AF3
Number of Residues	6
Details	binding site for residue CA G 204

Chain	Residue
G	ASP21
G	ASP23
G	ASP25
G	THR27
G	GLU32
G	HOH334

---

site_id	AF4
Number of Residues	6
Details	binding site for residue CA G 205

Chain	Residue
G	ASP130
G	ASP132
G	ASP134
G	GLN136
G	GLU141
G	HOH399

---

site_id	AF5
Number of Residues	2
Details	binding site for residue CL G 206

Chain	Residue
E	ARG91
G	ARG87

---

site_id	AF6
Number of Residues	2
Details	binding site for residue NA G 207

Chain	Residue
E	ARG107
G	ASP79

---

site_id	AF7
Number of Residues	5
Details	binding site for residue CL H 601

Chain	Residue
H	GLN575
H	GLY578
H	LEU579
H	ILE580
H	GLN581

---

Functional Information from PROSITE/UniProt

site_id	PS00018
Number of Residues	13
Details	EF_HAND_1 EF-hand calcium-binding domain. DKDGDGTITtkEL

Chain	Residue	Details
A	ASP21-LEU33
A	ASP57-PHE69
A	ASP94-LEU106
A	ASP130-PHE142

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	40
Details	BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00448, ECO:0000269|PubMed:1474585, ECO:0000269|PubMed:25441029, ECO:0000269|PubMed:27564677, ECO:0007744|PDB:1CLL, ECO:0007744|PDB:4UMO, ECO:0007744|PDB:4V0C, ECO:0007744|PDB:5J03

Chain	Residue	Details
A	ASP21
A	GLU68
C	ASP21
C	ASP23
C	ASP25
C	THR27
C	GLU32
C	ASP57
C	ASP59
C	ASN61
C	THR63
A	ASP23
C	GLU68
E	ASP21
E	ASP23
E	ASP25
E	THR27
E	GLU32
E	ASP57
E	ASP59
E	ASN61
E	THR63
A	ASP25
E	GLU68
G	ASP21
G	ASP23
G	ASP25
G	THR27
G	GLU32
G	ASP57
G	ASP59
G	ASN61
G	THR63
A	THR27
G	GLU68
A	GLU32
A	ASP57
A	ASP59
A	ASN61
A	THR63

---

site_id	SWS_FT_FI2
Number of Residues	40
Details	BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00448, ECO:0000269|PubMed:1474585, ECO:0000269|PubMed:27564677, ECO:0007744|PDB:1CLL, ECO:0007744|PDB:5J03

Chain	Residue	Details
A	ASP94
A	GLU141
C	ASP94
C	ASP96
C	ASN98
C	TYR100
C	GLU105
C	ASP130
C	ASP132
C	ASP134
C	GLN136
A	ASP96
C	GLU141
E	ASP94
E	ASP96
E	ASN98
E	TYR100
E	GLU105
E	ASP130
E	ASP132
E	ASP134
E	GLN136
A	ASN98
E	GLU141
G	ASP94
G	ASP96
G	ASN98
G	TYR100
G	GLU105
G	ASP130
G	ASP132
G	ASP134
G	GLN136
A	TYR100
G	GLU141
A	GLU105
A	ASP130
A	ASP132
A	ASP134
A	GLN136

---

site_id	SWS_FT_FI3
Number of Residues	4
Details	MOD_RES: N-acetylalanine => ECO:0000269|PubMed:7093203, ECO:0000269|Ref.7, ECO:0007744|PubMed:19413330, ECO:0007744|PubMed:22223895, ECO:0007744|PubMed:22814378, ECO:0007744|PubMed:25944712

Chain	Residue	Details
A	ALA2
C	ALA2
E	ALA2
G	ALA2

---

site_id	SWS_FT_FI4
Number of Residues	4
Details	MOD_RES: N6-acetyllysine; alternate => ECO:0007744|PubMed:19608861

Chain	Residue	Details
A	LYS22
C	LYS22
E	LYS22
G	LYS22

---

site_id	SWS_FT_FI5
Number of Residues	4
Details	MOD_RES: Phosphothreonine; by CaMK4 => ECO:0000250|UniProtKB:P0DP29

Chain	Residue	Details
A	THR45
C	THR45
E	THR45
G	THR45

---

site_id	SWS_FT_FI6
Number of Residues	4
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:23186163

Chain	Residue	Details
A	SER82
C	SER82
E	SER82
G	SER82

---

site_id	SWS_FT_FI7
Number of Residues	4
Details	MOD_RES: N6-acetyllysine => ECO:0007744|PubMed:19608861

Chain	Residue	Details
A	LYS95
C	LYS95
E	LYS95
G	LYS95

---

site_id	SWS_FT_FI8
Number of Residues	4
Details	MOD_RES: Phosphotyrosine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:19690332

Chain	Residue	Details
A	TYR100
C	TYR100
E	TYR100
G	TYR100

---

site_id	SWS_FT_FI9
Number of Residues	4
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163, ECO:0007744|PubMed:24275569

Chain	Residue	Details
A	SER102
C	SER102
E	SER102
G	SER102

---

site_id	SWS_FT_FI10
Number of Residues	4
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:24275569

Chain	Residue	Details
A	THR111
C	THR111
E	THR111
G	THR111

---

site_id	SWS_FT_FI11
Number of Residues	4
Details	MOD_RES: N6-methyllysine; alternate => ECO:0007744|PubMed:24129315

Chain	Residue	Details
A	LYS116
C	LYS116
E	LYS116
G	LYS116

---

site_id	SWS_FT_FI12
Number of Residues	4
Details	MOD_RES: Phosphotyrosine => ECO:0007744|PubMed:19690332

Chain	Residue	Details
A	TYR139
C	TYR139
E	TYR139
G	TYR139

---

site_id	SWS_FT_FI13
Number of Residues	8
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin); alternate => ECO:0000250|UniProtKB:P62157

Chain	Residue	Details
A	LYS22
C	LYS22
E	LYS22
G	LYS22

---