Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004067 | molecular_function | asparaginase activity |
| A | 0016787 | molecular_function | hydrolase activity |
| B | 0004067 | molecular_function | asparaginase activity |
| B | 0016787 | molecular_function | hydrolase activity |
| C | 0004067 | molecular_function | asparaginase activity |
| C | 0016787 | molecular_function | hydrolase activity |
| D | 0004067 | molecular_function | asparaginase activity |
| D | 0016787 | molecular_function | hydrolase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 11 |
| Details | binding site for residue ASN A 601 |
| Chain | Residue |
| A | GLY18 |
| A | HOH765 |
| D | TYR308 |
| A | ALA19 |
| A | ASP84 |
| A | SER85 |
| A | GLY115 |
| A | THR116 |
| A | ASP117 |
| A | ALA142 |
| A | GLN143 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 602 |
| Chain | Residue |
| A | GLU131 |
| A | TYR334 |
| A | ARG355 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 603 |
| Chain | Residue |
| A | PRO204 |
| A | THR207 |
| A | THR213 |
| A | ALA215 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | binding site for residue EDO A 604 |
| Chain | Residue |
| A | ASN201 |
| A | SER297 |
| A | CYS299 |
| A | LEU300 |
| A | GLY302 |
| A | MET323 |
| A | HOH702 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 605 |
| Chain | Residue |
| A | ASN233 |
| A | MET234 |
| A | GLU235 |
| A | HOH778 |
| A | HOH781 |
| B | ASP278 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 606 |
| Chain | Residue |
| A | SER178 |
| A | VAL208 |
| A | GLY209 |
| B | LYS193 |
| B | PHE194 |
| B | GLU195 |
| site_id | AC7 |
| Number of Residues | 11 |
| Details | binding site for residue ASN B 601 |
| Chain | Residue |
| B | GLY18 |
| B | ALA19 |
| B | MET22 |
| B | ASP84 |
| B | SER85 |
| B | GLY115 |
| B | THR116 |
| B | ASP117 |
| B | ALA142 |
| B | HOH789 |
| C | TYR308 |
| site_id | AC8 |
| Number of Residues | 7 |
| Details | binding site for residue EDO B 602 |
| Chain | Residue |
| B | GLY21 |
| B | GLN23 |
| B | GLY32 |
| B | PRO33 |
| B | GLY34 |
| B | ARG147 |
| B | HOH757 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | binding site for residue EDO B 603 |
| Chain | Residue |
| B | GLU131 |
| B | TYR334 |
| B | LEU354 |
| B | ARG355 |
| site_id | AD1 |
| Number of Residues | 3 |
| Details | binding site for residue EDO B 604 |
| Chain | Residue |
| B | PRO204 |
| B | THR207 |
| B | THR213 |
| site_id | AD2 |
| Number of Residues | 7 |
| Details | binding site for residue EDO B 605 |
| Chain | Residue |
| B | ASN201 |
| B | SER297 |
| B | CYS299 |
| B | LEU300 |
| B | GLY302 |
| B | MET323 |
| B | HOH704 |
| site_id | AD3 |
| Number of Residues | 13 |
| Details | binding site for residue ASN C 601 |
| Chain | Residue |
| B | TYR308 |
| B | HOH718 |
| C | GLY18 |
| C | ALA19 |
| C | MET22 |
| C | ASP84 |
| C | SER85 |
| C | GLY115 |
| C | THR116 |
| C | ASP117 |
| C | ALA142 |
| C | GLN143 |
| C | HOH771 |
| site_id | AD4 |
| Number of Residues | 7 |
| Details | binding site for residue EDO C 602 |
| Chain | Residue |
| C | ASN201 |
| C | SER297 |
| C | CYS299 |
| C | LEU300 |
| C | GLY302 |
| C | HOH706 |
| C | HOH717 |
| site_id | AD5 |
| Number of Residues | 3 |
| Details | binding site for residue EDO C 603 |
| Chain | Residue |
| C | PRO204 |
| C | THR207 |
| C | ALA215 |
| site_id | AD6 |
| Number of Residues | 3 |
| Details | binding site for residue EDO C 604 |
| Chain | Residue |
| C | GLU131 |
| C | TYR334 |
| C | ARG355 |
| site_id | AD7 |
| Number of Residues | 2 |
| Details | binding site for residue EDO C 605 |
| Chain | Residue |
| C | ARG220 |
| C | LYS221 |
| site_id | AD8 |
| Number of Residues | 13 |
| Details | binding site for residue ASN D 601 |
| Chain | Residue |
| D | GLY18 |
| D | ALA19 |
| D | MET22 |
| D | ASP84 |
| D | SER85 |
| D | GLY115 |
| D | THR116 |
| D | ASP117 |
| D | ALA142 |
| D | GLN143 |
| D | HOH784 |
| A | ASN272 |
| A | TYR308 |
| site_id | AD9 |
| Number of Residues | 6 |
| Details | binding site for residue EDO D 602 |
| Chain | Residue |
| D | GLY21 |
| D | GLY32 |
| D | PRO33 |
| D | GLY34 |
| D | ARG147 |
| D | HOH742 |
| site_id | AE1 |
| Number of Residues | 6 |
| Details | binding site for residue EDO D 603 |
| Chain | Residue |
| C | SER178 |
| C | VAL208 |
| C | GLY209 |
| D | LYS193 |
| D | PHE194 |
| D | GLU195 |
| site_id | AE2 |
| Number of Residues | 3 |
| Details | binding site for residue EDO D 604 |
| Chain | Residue |
| D | GLU131 |
| D | TYR334 |
| D | ARG355 |
| site_id | AE3 |
| Number of Residues | 8 |
| Details | binding site for residue EDO D 605 |
| Chain | Residue |
| D | ASN201 |
| D | SER297 |
| D | CYS299 |
| D | LEU300 |
| D | GLY302 |
| D | MET323 |
| D | HOH712 |
| D | HOH744 |
Functional Information from PROSITE/UniProt
| site_id | PS00917 |
| Number of Residues | 11 |
| Details | ASN_GLN_ASE_2 Asparaginase / glutaminase active site signature 2. GfVviHGTDTM |
| Chain | Residue | Details |
| A | GLY109-MET119 | |
