5DN6

ATP synthase from Paracoccus denitrificans

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005524	molecular_function	ATP binding
A	0005886	cellular_component	plasma membrane
A	0006754	biological_process	ATP biosynthetic process
A	0015986	biological_process	proton motive force-driven ATP synthesis
A	0032559	molecular_function	adenyl ribonucleotide binding
A	0043531	molecular_function	ADP binding
A	0045259	cellular_component	proton-transporting ATP synthase complex
A	0045261	cellular_component	proton-transporting ATP synthase complex, catalytic core F(1)
A	0046034	biological_process	ATP metabolic process
A	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
A	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
A	1902600	biological_process	proton transmembrane transport
B	0005524	molecular_function	ATP binding
B	0005886	cellular_component	plasma membrane
B	0006754	biological_process	ATP biosynthetic process
B	0015986	biological_process	proton motive force-driven ATP synthesis
B	0032559	molecular_function	adenyl ribonucleotide binding
B	0043531	molecular_function	ADP binding
B	0045259	cellular_component	proton-transporting ATP synthase complex
B	0045261	cellular_component	proton-transporting ATP synthase complex, catalytic core F(1)
B	0046034	biological_process	ATP metabolic process
B	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
B	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
B	1902600	biological_process	proton transmembrane transport
C	0005524	molecular_function	ATP binding
C	0005886	cellular_component	plasma membrane
C	0006754	biological_process	ATP biosynthetic process
C	0015986	biological_process	proton motive force-driven ATP synthesis
C	0032559	molecular_function	adenyl ribonucleotide binding
C	0043531	molecular_function	ADP binding
C	0045259	cellular_component	proton-transporting ATP synthase complex
C	0045261	cellular_component	proton-transporting ATP synthase complex, catalytic core F(1)
C	0046034	biological_process	ATP metabolic process
C	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
C	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
C	1902600	biological_process	proton transmembrane transport
D	0005524	molecular_function	ATP binding
D	0005886	cellular_component	plasma membrane
D	0006754	biological_process	ATP biosynthetic process
D	0015986	biological_process	proton motive force-driven ATP synthesis
D	0016887	molecular_function	ATP hydrolysis activity
D	0045259	cellular_component	proton-transporting ATP synthase complex
D	0045261	cellular_component	proton-transporting ATP synthase complex, catalytic core F(1)
D	0046034	biological_process	ATP metabolic process
D	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
D	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
D	1902600	biological_process	proton transmembrane transport
E	0005524	molecular_function	ATP binding
E	0005886	cellular_component	plasma membrane
E	0006754	biological_process	ATP biosynthetic process
E	0015986	biological_process	proton motive force-driven ATP synthesis
E	0016887	molecular_function	ATP hydrolysis activity
E	0045259	cellular_component	proton-transporting ATP synthase complex
E	0045261	cellular_component	proton-transporting ATP synthase complex, catalytic core F(1)
E	0046034	biological_process	ATP metabolic process
E	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
E	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
E	1902600	biological_process	proton transmembrane transport
F	0005524	molecular_function	ATP binding
F	0005886	cellular_component	plasma membrane
F	0006754	biological_process	ATP biosynthetic process
F	0015986	biological_process	proton motive force-driven ATP synthesis
F	0016887	molecular_function	ATP hydrolysis activity
F	0045259	cellular_component	proton-transporting ATP synthase complex
F	0045261	cellular_component	proton-transporting ATP synthase complex, catalytic core F(1)
F	0046034	biological_process	ATP metabolic process
F	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
F	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
F	1902600	biological_process	proton transmembrane transport
G	0005524	molecular_function	ATP binding
G	0005886	cellular_component	plasma membrane
G	0006754	biological_process	ATP biosynthetic process
G	0015986	biological_process	proton motive force-driven ATP synthesis
G	0042777	biological_process	proton motive force-driven plasma membrane ATP synthesis
G	0045261	cellular_component	proton-transporting ATP synthase complex, catalytic core F(1)
G	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
G	1902600	biological_process	proton transmembrane transport
H	0005886	cellular_component	plasma membrane
H	0006754	biological_process	ATP biosynthetic process
H	0009772	biological_process	photosynthetic electron transport in photosystem II
H	0009773	biological_process	photosynthetic electron transport in photosystem I
H	0015986	biological_process	proton motive force-driven ATP synthesis
H	0016020	cellular_component	membrane
H	0045261	cellular_component	proton-transporting ATP synthase complex, catalytic core F(1)
H	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
H	1902600	biological_process	proton transmembrane transport
I	0005524	molecular_function	ATP binding
I	0005886	cellular_component	plasma membrane
I	0006754	biological_process	ATP biosynthetic process
I	0015986	biological_process	proton motive force-driven ATP synthesis
I	0045261	cellular_component	proton-transporting ATP synthase complex, catalytic core F(1)
I	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
I	1902600	biological_process	proton transmembrane transport
J	0005886	cellular_component	plasma membrane
J	0006754	biological_process	ATP biosynthetic process
J	0008289	molecular_function	lipid binding
J	0015078	molecular_function	proton transmembrane transporter activity
J	0015986	biological_process	proton motive force-driven ATP synthesis
J	0033177	cellular_component	proton-transporting two-sector ATPase complex, proton-transporting domain
J	0045263	cellular_component	proton-transporting ATP synthase complex, coupling factor F(o)
J	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
J	1902600	biological_process	proton transmembrane transport
K	0005886	cellular_component	plasma membrane
K	0006754	biological_process	ATP biosynthetic process
K	0008289	molecular_function	lipid binding
K	0015078	molecular_function	proton transmembrane transporter activity
K	0015986	biological_process	proton motive force-driven ATP synthesis
K	0033177	cellular_component	proton-transporting two-sector ATPase complex, proton-transporting domain
K	0045263	cellular_component	proton-transporting ATP synthase complex, coupling factor F(o)
K	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
K	1902600	biological_process	proton transmembrane transport
L	0005886	cellular_component	plasma membrane
L	0006754	biological_process	ATP biosynthetic process
L	0008289	molecular_function	lipid binding
L	0015078	molecular_function	proton transmembrane transporter activity
L	0015986	biological_process	proton motive force-driven ATP synthesis
L	0033177	cellular_component	proton-transporting two-sector ATPase complex, proton-transporting domain
L	0045263	cellular_component	proton-transporting ATP synthase complex, coupling factor F(o)
L	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
L	1902600	biological_process	proton transmembrane transport
M	0005886	cellular_component	plasma membrane
M	0006754	biological_process	ATP biosynthetic process
M	0008289	molecular_function	lipid binding
M	0015078	molecular_function	proton transmembrane transporter activity
M	0015986	biological_process	proton motive force-driven ATP synthesis
M	0033177	cellular_component	proton-transporting two-sector ATPase complex, proton-transporting domain
M	0045263	cellular_component	proton-transporting ATP synthase complex, coupling factor F(o)
M	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
M	1902600	biological_process	proton transmembrane transport
N	0005886	cellular_component	plasma membrane
N	0006754	biological_process	ATP biosynthetic process
N	0008289	molecular_function	lipid binding
N	0015078	molecular_function	proton transmembrane transporter activity
N	0015986	biological_process	proton motive force-driven ATP synthesis
N	0033177	cellular_component	proton-transporting two-sector ATPase complex, proton-transporting domain
N	0045263	cellular_component	proton-transporting ATP synthase complex, coupling factor F(o)
N	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
N	1902600	biological_process	proton transmembrane transport
O	0005886	cellular_component	plasma membrane
O	0006754	biological_process	ATP biosynthetic process
O	0008289	molecular_function	lipid binding
O	0015078	molecular_function	proton transmembrane transporter activity
O	0015986	biological_process	proton motive force-driven ATP synthesis
O	0033177	cellular_component	proton-transporting two-sector ATPase complex, proton-transporting domain
O	0045263	cellular_component	proton-transporting ATP synthase complex, coupling factor F(o)
O	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
O	1902600	biological_process	proton transmembrane transport
P	0005886	cellular_component	plasma membrane
P	0006754	biological_process	ATP biosynthetic process
P	0008289	molecular_function	lipid binding
P	0015078	molecular_function	proton transmembrane transporter activity
P	0015986	biological_process	proton motive force-driven ATP synthesis
P	0033177	cellular_component	proton-transporting two-sector ATPase complex, proton-transporting domain
P	0045263	cellular_component	proton-transporting ATP synthase complex, coupling factor F(o)
P	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
P	1902600	biological_process	proton transmembrane transport
Q	0005886	cellular_component	plasma membrane
Q	0006754	biological_process	ATP biosynthetic process
Q	0008289	molecular_function	lipid binding
Q	0015078	molecular_function	proton transmembrane transporter activity
Q	0015986	biological_process	proton motive force-driven ATP synthesis
Q	0033177	cellular_component	proton-transporting two-sector ATPase complex, proton-transporting domain
Q	0045263	cellular_component	proton-transporting ATP synthase complex, coupling factor F(o)
Q	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
Q	1902600	biological_process	proton transmembrane transport
R	0005886	cellular_component	plasma membrane
R	0006754	biological_process	ATP biosynthetic process
R	0008289	molecular_function	lipid binding
R	0015078	molecular_function	proton transmembrane transporter activity
R	0015986	biological_process	proton motive force-driven ATP synthesis
R	0033177	cellular_component	proton-transporting two-sector ATPase complex, proton-transporting domain
R	0045263	cellular_component	proton-transporting ATP synthase complex, coupling factor F(o)
R	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
R	1902600	biological_process	proton transmembrane transport
S	0005886	cellular_component	plasma membrane
S	0006754	biological_process	ATP biosynthetic process
S	0008289	molecular_function	lipid binding
S	0015078	molecular_function	proton transmembrane transporter activity
S	0015986	biological_process	proton motive force-driven ATP synthesis
S	0033177	cellular_component	proton-transporting two-sector ATPase complex, proton-transporting domain
S	0045263	cellular_component	proton-transporting ATP synthase complex, coupling factor F(o)
S	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
S	1902600	biological_process	proton transmembrane transport
T	0005886	cellular_component	plasma membrane
T	0006754	biological_process	ATP biosynthetic process
T	0008289	molecular_function	lipid binding
T	0015078	molecular_function	proton transmembrane transporter activity
T	0015986	biological_process	proton motive force-driven ATP synthesis
T	0033177	cellular_component	proton-transporting two-sector ATPase complex, proton-transporting domain
T	0045263	cellular_component	proton-transporting ATP synthase complex, coupling factor F(o)
T	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
T	1902600	biological_process	proton transmembrane transport
U	0005886	cellular_component	plasma membrane
U	0006754	biological_process	ATP biosynthetic process
U	0008289	molecular_function	lipid binding
U	0015078	molecular_function	proton transmembrane transporter activity
U	0015986	biological_process	proton motive force-driven ATP synthesis
U	0033177	cellular_component	proton-transporting two-sector ATPase complex, proton-transporting domain
U	0045263	cellular_component	proton-transporting ATP synthase complex, coupling factor F(o)
U	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
U	1902600	biological_process	proton transmembrane transport
X	0005886	cellular_component	plasma membrane
X	0006754	biological_process	ATP biosynthetic process
X	0015078	molecular_function	proton transmembrane transporter activity
X	0015986	biological_process	proton motive force-driven ATP synthesis
X	0045263	cellular_component	proton-transporting ATP synthase complex, coupling factor F(o)
X	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
X	1902600	biological_process	proton transmembrane transport
Z	0140678	molecular_function	molecular function inhibitor activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	8
Details	binding site for residue ATP A 600

Chain	Residue
A	ARG171
A	GLY174
A	LYS175
A	THR176
A	ALA177
A	PHE358
A	GLN433
A	MG601

---

site_id	AC2
Number of Residues	2
Details	binding site for residue MG A 601

Chain	Residue
A	ATP600
A	THR176

---

site_id	AC3
Number of Residues	12
Details	binding site for residue ADP B 600

Chain	Residue
B	GLN172
B	THR173
B	GLY174
B	LYS175
B	THR176
B	ALA177
B	PHE358
B	ARG363
B	GLN431
B	GLN433
B	MG601
E	ARG352

---

site_id	AC4
Number of Residues	3
Details	binding site for residue MG B 601

Chain	Residue
B	THR176
B	ASP270
B	ADP600

---

site_id	AC5
Number of Residues	14
Details	binding site for residue ATP C 600

Chain	Residue
C	GLN172
C	THR173
C	GLY174
C	LYS175
C	THR176
C	ALA177
C	GLU329
C	PHE358
C	ARG363
C	PRO364
C	GLN431
C	GLN433
C	MG601
F	TYR364

---

site_id	AC6
Number of Residues	2
Details	binding site for residue MG C 601

Chain	Residue
C	THR176
C	ATP600

---

site_id	AC7
Number of Residues	15
Details	binding site for residue ATP D 600

Chain	Residue
C	SER373
C	ARG374
D	GLY152
D	GLY154
D	VAL155
D	GLY156
D	LYS157
D	THR158
D	VAL159
D	ARG184
D	GLU187
D	TYR341
D	ALA417
D	PHE420
D	MG601

---

site_id	AC8
Number of Residues	6
Details	binding site for residue MG D 601

Chain	Residue
D	THR158
D	GLU183
D	ARG184
D	GLU187
D	ASP252
D	ATP600

---

site_id	AC9
Number of Residues	18
Details	binding site for residue ATP F 600

Chain	Residue
B	SER345
B	VAL372
B	ARG374
F	GLY152
F	GLY154
F	VAL155
F	GLY156
F	LYS157
F	THR158
F	VAL159
F	GLU183
F	ARG184
F	ASP252
F	TYR341
F	PHE414
F	PHE420
F	THR421
F	MG601

---

site_id	AD1
Number of Residues	5
Details	binding site for residue MG F 601

Chain	Residue
F	THR158
F	GLU183
F	GLU187
F	ASP252
F	ATP600

---

Functional Information from PROSITE/UniProt

site_id	PS00152
Number of Residues	10
Details	ATPASE_ALPHA_BETA ATP synthase alpha and beta subunits signature. PAVNTGLSVS

Chain	Residue	Details
A	PRO364-SER373
D	PRO342-SER351

---

site_id	PS00449
Number of Residues	10
Details	ATPASE_A ATP synthase a subunit signature. SHSIRLAGNI

Chain	Residue	Details
X	SER1213-ILE1222

---

site_id	PS00389
Number of Residues	20
Details	ATPASE_DELTA ATP synthase delta (OSCP) subunit signature. VkLnarVDeSLiGGMIVKlG

Chain	Residue	Details
H	VAL145-GLY164

---

site_id	PS00153
Number of Residues	14
Details	ATPASE_GAMMA ATP synthase gamma subunit signature. ITkEliEiisGAeA

Chain	Residue	Details
G	ILE276-ALA289

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	120
Details	TRANSMEM: Helical => ECO:0000255|HAMAP-Rule:MF_01393

Chain	Residue	Details
X	THR1069-GLY1089
X	TYR1126-LEU1146
X	ILE1156-VAL1176
X	PHE1182-ILE1202
X	VAL1231-ALA1251
X	LEU1255-LEU1275

---

site_id	SWS_FT_FI2
Number of Residues	3
Details	SITE: Required for activity => ECO:0000255|HAMAP-Rule:MF_01346

Chain	Residue	Details
A	SER371
B	SER371
C	SER371

---