Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000105 | biological_process | L-histidine biosynthetic process |
| A | 0000162 | biological_process | tryptophan biosynthetic process |
| A | 0003949 | molecular_function | 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase activity |
| A | 0004640 | molecular_function | phosphoribosylanthranilate isomerase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0016853 | molecular_function | isomerase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 10 |
| Details | binding site for residue SO4 A 301 |
| Chain | Residue |
| A | ARG19 |
| A | HOH496 |
| A | ASP171 |
| A | GLY172 |
| A | GLY197 |
| A | GLY198 |
| A | GLY222 |
| A | LYS223 |
| A | HOH419 |
| A | HOH481 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 A 302 |
| Chain | Residue |
| A | LEU66 |
| A | GLU69 |
| A | TYR149 |
| A | GLU150 |
| A | ASP153 |
| A | HOH525 |
| site_id | AC3 |
| Number of Residues | 9 |
| Details | binding site for residue GOL A 303 |
| Chain | Residue |
| A | VAL165 |
| A | ASP167 |
| A | PRO177 |
| A | ASN178 |
| A | LEU181 |
| A | LEU182 |
| A | SER196 |
| A | GLY197 |
| A | HOH487 |
| site_id | AC4 |
| Number of Residues | 16 |
| Details | binding site for residue AMZ A 304 |
| Chain | Residue |
| A | LEU20 |
| A | GLY23 |
| A | LEU54 |
| A | PHE58 |
| A | SER81 |
| A | GLY83 |
| A | ARG85 |
| A | GLY104 |
| A | THR105 |
| A | ASP130 |
| A | GLY140 |
| A | HOH402 |
| A | HOH405 |
| A | HOH410 |
| A | HOH425 |
| A | HOH453 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | ACT_SITE: Proton acceptor => ECO:0000250 |
| Chain | Residue | Details |
| A | ASP11 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | ACT_SITE: Proton donor => ECO:0000250 |
| Chain | Residue | Details |
| A | ASP130 | |
