5DIT
The Fk1 domain of FKBP51 in complex with the new synthetic ligand (1R)-3-(3,4-dimethoxyphenyl)-1-f3-[2-(morpholin-4-yl)ethoxy]phenylgpropyl(2S)-1-[(2S,3R)-2-cyclohexyl-3-hydroxybutanoyl]piperidine-2-carboxylate
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003755 | molecular_function | peptidyl-prolyl cis-trans isomerase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 17 |
| Details | binding site for residue 5B8 A 201 |
| Chain | Residue |
| A | GLU20 |
| A | VAL86 |
| A | ILE87 |
| A | TRP90 |
| A | ALA112 |
| A | TYR113 |
| A | LYS121 |
| A | ILE122 |
| A | PHE130 |
| A | GLN21 |
| A | TYR57 |
| A | GLY59 |
| A | LYS60 |
| A | VAL78 |
| A | PHE79 |
| A | GLY84 |
| A | GLN85 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | MOD_RES: N6-acetyllysine => ECO:0000269|PubMed:28147277 |
| Chain | Residue | Details |
| A | LYS28 |
