5DIE
Crystal Structure of the ER-alpha Ligand-binding Domain in complex with a trifluoro-substituted A-CD ring estrogen derivative (1S,3aR,5S,7aS)-7a-methyl-5-(2,3,5-trifluoro-4-hydroxyphenyl)octahydro-1H-inden-1-ol
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 12 |
Details | binding site for residue 5CJ A 601 |
Chain | Residue |
A | MET343 |
A | GLY521 |
A | HIS524 |
A | HOH718 |
A | LEU346 |
A | LEU349 |
A | ALA350 |
A | GLU353 |
A | LEU387 |
A | MET388 |
A | LEU391 |
A | ARG394 |
site_id | AC2 |
Number of Residues | 12 |
Details | binding site for residue 5CJ B 601 |
Chain | Residue |
B | LEU346 |
B | LEU349 |
B | ALA350 |
B | GLU353 |
B | LEU387 |
B | MET388 |
B | LEU391 |
B | ARG394 |
B | MET421 |
B | GLY521 |
B | HIS524 |
B | HOH707 |
Functional Information from SwissProt/UniProt
Chain | Residue | Details |
C | SER699 | |
D | SER699 | |
A | HIS524 | |
B | GLU353 | |
B | ARG394 | |
B | HIS524 | |
Chain | Residue | Details |
A | SER537 | |
B | SER537 | |
site_id | SWS_FT_FI3 |
Number of Residues | 2 |
Details | LIPID: S-palmitoyl cysteine => ECO:0000250 |
Chain | Residue | Details |
A | CYS447 | |
B | CYS447 | |