5DHL
Crystal structure of Toxin, mutant N197W
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005576 | cellular_component | extracellular region |
| A | 0008289 | molecular_function | lipid binding |
| A | 0015485 | molecular_function | cholesterol binding |
| A | 0016020 | cellular_component | membrane |
| A | 0020002 | cellular_component | host cell plasma membrane |
| A | 0031640 | biological_process | killing of cells of another organism |
| A | 0035821 | biological_process | modulation of process of another organism |
| A | 0044179 | biological_process | hemolysis in another organism |
| A | 0090729 | molecular_function | toxin activity |
| B | 0005576 | cellular_component | extracellular region |
| B | 0008289 | molecular_function | lipid binding |
| B | 0015485 | molecular_function | cholesterol binding |
| B | 0016020 | cellular_component | membrane |
| B | 0020002 | cellular_component | host cell plasma membrane |
| B | 0031640 | biological_process | killing of cells of another organism |
| B | 0035821 | biological_process | modulation of process of another organism |
| B | 0044179 | biological_process | hemolysis in another organism |
| B | 0090729 | molecular_function | toxin activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | binding site for residue EPE A 601 |
| Chain | Residue |
| A | SER88 |
| A | PRO89 |
| A | TRP197 |
| B | TYR432 |
| B | TRP464 |
| B | GLU465 |
| B | HOH722 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | binding site for residue EPE B 601 |
| Chain | Residue |
| A | GLU465 |
| A | HOH713 |
| B | THR87 |
| B | SER88 |
| B | PRO89 |
| B | TRP197 |
| A | TYR432 |
| A | TRP464 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 86 |
| Details | TRANSMEM: Beta stranded => ECO:0000250|UniProtKB:Q04IN8 |
| Chain | Residue | Details |
| A | LYS189-VAL202 | |
| A | VAL209-GLU218 | |
| A | SER287-ALA296 | |
| A | LYS304-SER316 | |
| B | LYS189-VAL202 | |
| B | VAL209-GLU218 | |
| B | SER287-ALA296 | |
| B | LYS304-SER316 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | SITE: Important for cholesterol binding => ECO:0000305|PubMed:2888650 |
| Chain | Residue | Details |
| A | ALA459 | |
| B | ALA459 |
