5DFS
Crystal structure of Spider Monkey Cytochrome C at 1.15 Angstrom
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005739 | cellular_component | mitochondrion |
| A | 0005758 | cellular_component | mitochondrial intermembrane space |
| A | 0005829 | cellular_component | cytosol |
| A | 0006122 | biological_process | mitochondrial electron transport, ubiquinol to cytochrome c |
| A | 0006123 | biological_process | mitochondrial electron transport, cytochrome c to oxygen |
| A | 0006915 | biological_process | apoptotic process |
| A | 0009055 | molecular_function | electron transfer activity |
| A | 0020037 | molecular_function | heme binding |
| A | 0043280 | biological_process | positive regulation of cysteine-type endopeptidase activity involved in apoptotic process |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0005739 | cellular_component | mitochondrion |
| B | 0005758 | cellular_component | mitochondrial intermembrane space |
| B | 0005829 | cellular_component | cytosol |
| B | 0006122 | biological_process | mitochondrial electron transport, ubiquinol to cytochrome c |
| B | 0006123 | biological_process | mitochondrial electron transport, cytochrome c to oxygen |
| B | 0006915 | biological_process | apoptotic process |
| B | 0009055 | molecular_function | electron transfer activity |
| B | 0020037 | molecular_function | heme binding |
| B | 0043280 | biological_process | positive regulation of cysteine-type endopeptidase activity involved in apoptotic process |
| B | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 21 |
| Details | binding site for residue HEC A 201 |
| Chain | Residue |
| A | LYS13 |
| A | TYR48 |
| A | THR49 |
| A | ASN52 |
| A | TRP59 |
| A | TYR67 |
| A | THR78 |
| A | LYS79 |
| A | MET80 |
| A | ILE81 |
| A | PHE82 |
| A | CYS14 |
| A | HOH334 |
| B | LYS55 |
| A | CYS17 |
| A | HIS18 |
| A | THR28 |
| A | GLY29 |
| A | PRO30 |
| A | THR40 |
| A | GLY41 |
| site_id | AC2 |
| Number of Residues | 2 |
| Details | binding site for residue EDO A 202 |
| Chain | Residue |
| A | GLY1 |
| A | HOH326 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 203 |
| Chain | Residue |
| A | LYS55 |
| A | HOH301 |
| A | HOH306 |
| A | HOH409 |
| site_id | AC4 |
| Number of Residues | 2 |
| Details | binding site for residue CL A 204 |
| Chain | Residue |
| A | GLU61 |
| A | LYS99 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | binding site for residue CL A 205 |
| Chain | Residue |
| A | GLU50 |
| A | HOH395 |
| A | HOH422 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | binding site for residue EDO B 202 |
| Chain | Residue |
| A | LYS39 |
| B | LYS13 |
| B | HOH304 |
| B | HOH375 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | binding site for residue EDO B 203 |
| Chain | Residue |
| B | LYS87 |
| B | LYS88 |
| B | GLU89 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | binding site for residue EDO B 204 |
| Chain | Residue |
| B | LYS25 |
| B | HOH312 |
| B | HOH315 |
| B | HOH381 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | binding site for residue EDO B 205 |
| Chain | Residue |
| B | GLY60 |
| B | GLU61 |
| B | LYS99 |
| B | HOH306 |
| B | HOH310 |
| site_id | AD1 |
| Number of Residues | 23 |
| Details | binding site for Di-peptide HEM B 201 and CYS B 17 |
| Chain | Residue |
| B | LYS13 |
| B | CYS14 |
| B | SER15 |
| B | GLN16 |
| B | HIS18 |
| B | LYS27 |
| B | THR28 |
| B | GLY29 |
| B | PRO30 |
| B | THR40 |
| B | GLY41 |
| B | TYR48 |
| B | THR49 |
| B | ASN52 |
| B | TRP59 |
| B | TYR67 |
| B | THR78 |
| B | LYS79 |
| B | MET80 |
| B | ILE81 |
| B | PHE82 |
| B | HOH347 |
| B | HOH362 |
| site_id | AD2 |
| Number of Residues | 23 |
| Details | binding site for Di-peptide HEM B 201 and CYS B 14 |
| Chain | Residue |
| B | PHE10 |
| B | LYS13 |
| B | SER15 |
| B | GLN16 |
| B | CYS17 |
| B | HIS18 |
| B | THR28 |
| B | GLY29 |
| B | PRO30 |
| B | THR40 |
| B | GLY41 |
| B | TYR48 |
| B | THR49 |
| B | ASN52 |
| B | TRP59 |
| B | TYR67 |
| B | THR78 |
| B | LYS79 |
| B | MET80 |
| B | ILE81 |
| B | PHE82 |
| B | HOH347 |
| B | HOH362 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | BINDING: covalent |
| Chain | Residue | Details |
| A | CYS14 | |
| A | CYS17 | |
| B | CYS14 | |
| B | CYS17 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | BINDING: axial binding residue |
| Chain | Residue | Details |
| A | HIS18 | |
| A | MET80 | |
| B | HIS18 | |
| B | MET80 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | MOD_RES: N-acetylglycine => ECO:0000250|UniProtKB:P62894, ECO:0000305 |
| Chain | Residue | Details |
| A | GLY1 | |
| B | GLY1 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | MOD_RES: Phosphotyrosine => ECO:0000250|UniProtKB:P62894 |
| Chain | Residue | Details |
| A | TYR48 | |
| A | TYR97 | |
| B | TYR48 | |
| B | TYR97 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | MOD_RES: N6-succinyllysine => ECO:0000250|UniProtKB:P62897 |
| Chain | Residue | Details |
| A | LYS55 | |
| B | LYS55 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | MOD_RES: N6-succinyllysine; alternate => ECO:0000250|UniProtKB:P62897 |
| Chain | Residue | Details |
| A | LYS72 | |
| B | LYS72 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 2 |
| Details | MOD_RES: N6-acetyllysine => ECO:0000250|UniProtKB:P62897 |
| Chain | Residue | Details |
| A | LYS99 | |
| B | LYS99 |
