5DFB
Crystal structure of BRD2(BD2) mutant W370F in the free form
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | binding site for residue NI A 501 |
| Chain | Residue |
| A | ARG419 |
| A | ARG419 |
| A | HOH641 |
| A | HOH641 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | binding site for residue 2PE A 502 |
| Chain | Residue |
| A | HOH623 |
| A | HOH646 |
| A | HOH648 |
| A | SER347 |
| A | LYS351 |
| A | ASP385 |
| A | TYR428 |
| A | ASN429 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | binding site for residue GOL A 503 |
| Chain | Residue |
| A | LYS402 |
| A | ASP407 |
| A | MET438 |
| A | LYS441 |
| A | HOH601 |
| A | HOH615 |
Functional Information from PROSITE/UniProt
| site_id | PS00633 |
| Number of Residues | 60 |
| Details | BROMODOMAIN_1 Bromodomain signature. AfpFykpvDasalglhDYHdiIkhpMdlstVkrkmenrd..Yrdaqefaadvrl.MfsNCykY |
| Chain | Residue | Details |
| A | ALA369-TYR428 |
