5DF7
CRYSTAL STRUCTURE OF PENICILLIN-BINDING PROTEIN 3 FROM PSEUDOMONAS AERUGINOSA IN COMPLEX WITH AZLOCILLIN
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000917 | biological_process | division septum assembly |
| A | 0004180 | molecular_function | carboxypeptidase activity |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0006508 | biological_process | proteolysis |
| A | 0008360 | biological_process | regulation of cell shape |
| A | 0008658 | molecular_function | penicillin binding |
| A | 0008955 | molecular_function | peptidoglycan glycosyltransferase activity |
| A | 0009002 | molecular_function | serine-type D-Ala-D-Ala carboxypeptidase activity |
| A | 0009252 | biological_process | peptidoglycan biosynthetic process |
| A | 0016757 | molecular_function | glycosyltransferase activity |
| A | 0043093 | biological_process | FtsZ-dependent cytokinesis |
| A | 0051301 | biological_process | cell division |
| A | 0071555 | biological_process | cell wall organization |
| B | 0000917 | biological_process | division septum assembly |
| B | 0004180 | molecular_function | carboxypeptidase activity |
| B | 0005886 | cellular_component | plasma membrane |
| B | 0006508 | biological_process | proteolysis |
| B | 0008360 | biological_process | regulation of cell shape |
| B | 0008658 | molecular_function | penicillin binding |
| B | 0008955 | molecular_function | peptidoglycan glycosyltransferase activity |
| B | 0009002 | molecular_function | serine-type D-Ala-D-Ala carboxypeptidase activity |
| B | 0009252 | biological_process | peptidoglycan biosynthetic process |
| B | 0016757 | molecular_function | glycosyltransferase activity |
| B | 0043093 | biological_process | FtsZ-dependent cytokinesis |
| B | 0051301 | biological_process | cell division |
| B | 0071555 | biological_process | cell wall organization |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 16 |
| Details | binding site for residue 59H A 601 |
| Chain | Residue |
| A | SER294 |
| A | ARG489 |
| A | TYR498 |
| A | PHE533 |
| A | GLY534 |
| A | HOH716 |
| A | HOH726 |
| A | HOH841 |
| A | TYR328 |
| A | SER349 |
| A | ASN351 |
| A | TYR409 |
| A | SER485 |
| A | GLY486 |
| A | THR487 |
| A | ALA488 |
| site_id | AC2 |
| Number of Residues | 9 |
| Details | binding site for residue GOL A 602 |
| Chain | Residue |
| A | GLY247 |
| A | SER248 |
| A | ARG284 |
| A | PHE290 |
| A | ARG504 |
| A | VAL523 |
| A | ASP525 |
| A | HOH731 |
| A | HOH757 |
| site_id | AC3 |
| Number of Residues | 2 |
| Details | binding site for residue CL A 603 |
| Chain | Residue |
| A | ARG499 |
| A | ASN501 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | binding site for residue IMD A 604 |
| Chain | Residue |
| A | ALA181 |
| A | PHE182 |
| A | LEU381 |
| site_id | AC5 |
| Number of Residues | 8 |
| Details | binding site for residue GOL B 602 |
| Chain | Residue |
| B | GLY247 |
| B | SER248 |
| B | ARG284 |
| B | PHE290 |
| B | ALA415 |
| B | VAL523 |
| B | ASP525 |
| B | HOH701 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | binding site for residue GOL B 603 |
| Chain | Residue |
| B | TYR268 |
| B | ASN269 |
| B | ASN272 |
| B | ARG273 |
| B | HOH716 |
| site_id | AC7 |
| Number of Residues | 2 |
| Details | binding site for residue CL B 604 |
| Chain | Residue |
| A | ARG175 |
| B | ARG473 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | binding site for residue CL B 605 |
| Chain | Residue |
| B | LYS490 |
| B | VAL491 |
| B | ARG504 |
| site_id | AC9 |
| Number of Residues | 3 |
| Details | binding site for residue CL B 606 |
| Chain | Residue |
| A | ARG473 |
| B | ARG175 |
| B | HOH802 |
| site_id | AD1 |
| Number of Residues | 4 |
| Details | binding site for residue IMD B 607 |
| Chain | Residue |
| B | ALA181 |
| B | PHE182 |
| B | LEU381 |
| B | HOH792 |
| site_id | AD2 |
| Number of Residues | 23 |
| Details | binding site for Di-peptide 59H B 601 and SER B 294 |
| Chain | Residue |
| B | PRO292 |
| B | GLY293 |
| B | THR295 |
| B | VAL296 |
| B | LYS297 |
| B | TYR328 |
| B | VAL333 |
| B | SER349 |
| B | ASN351 |
| B | TYR407 |
| B | TYR409 |
| B | LYS484 |
| B | SER485 |
| B | GLY486 |
| B | THR487 |
| B | ALA488 |
| B | ARG489 |
| B | TYR498 |
| B | PHE533 |
| B | GLY534 |
| B | HOH712 |
| B | HOH714 |
| B | HOH818 |
