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5DF5

The structure of oxidized rat cytochrome c (T28E) at 1.30 angstroms resolution.

Functional Information from GO Data
ChainGOidnamespacecontents
A0002931biological_processresponse to ischemia
A0005739cellular_componentmitochondrion
A0005758cellular_componentmitochondrial intermembrane space
A0005829cellular_componentcytosol
A0006122biological_processmitochondrial electron transport, ubiquinol to cytochrome c
A0006123biological_processmitochondrial electron transport, cytochrome c to oxygen
A0006915biological_processapoptotic process
A0006979biological_processresponse to oxidative stress
A0009055molecular_functionelectron transfer activity
A0009629biological_processresponse to gravity
A0010730biological_processnegative regulation of hydrogen peroxide biosynthetic process
A0019899molecular_functionenzyme binding
A0020037molecular_functionheme binding
A0034349biological_processglial cell apoptotic process
A0034465biological_processresponse to carbon monoxide
A0042743biological_processhydrogen peroxide metabolic process
A0043293cellular_componentapoptosome
A0046688biological_processresponse to copper ion
A0046872molecular_functionmetal ion binding
A0070469cellular_componentrespirasome
A1901857biological_processpositive regulation of cellular respiration
B0002931biological_processresponse to ischemia
B0005739cellular_componentmitochondrion
B0005758cellular_componentmitochondrial intermembrane space
B0005829cellular_componentcytosol
B0006122biological_processmitochondrial electron transport, ubiquinol to cytochrome c
B0006123biological_processmitochondrial electron transport, cytochrome c to oxygen
B0006915biological_processapoptotic process
B0006979biological_processresponse to oxidative stress
B0009055molecular_functionelectron transfer activity
B0009629biological_processresponse to gravity
B0010730biological_processnegative regulation of hydrogen peroxide biosynthetic process
B0019899molecular_functionenzyme binding
B0020037molecular_functionheme binding
B0034349biological_processglial cell apoptotic process
B0034465biological_processresponse to carbon monoxide
B0042743biological_processhydrogen peroxide metabolic process
B0043293cellular_componentapoptosome
B0046688biological_processresponse to copper ion
B0046872molecular_functionmetal ion binding
B0070469cellular_componentrespirasome
B1901857biological_processpositive regulation of cellular respiration
C0002931biological_processresponse to ischemia
C0005739cellular_componentmitochondrion
C0005758cellular_componentmitochondrial intermembrane space
C0005829cellular_componentcytosol
C0006122biological_processmitochondrial electron transport, ubiquinol to cytochrome c
C0006123biological_processmitochondrial electron transport, cytochrome c to oxygen
C0006915biological_processapoptotic process
C0006979biological_processresponse to oxidative stress
C0009055molecular_functionelectron transfer activity
C0009629biological_processresponse to gravity
C0010730biological_processnegative regulation of hydrogen peroxide biosynthetic process
C0019899molecular_functionenzyme binding
C0020037molecular_functionheme binding
C0034349biological_processglial cell apoptotic process
C0034465biological_processresponse to carbon monoxide
C0042743biological_processhydrogen peroxide metabolic process
C0043293cellular_componentapoptosome
C0046688biological_processresponse to copper ion
C0046872molecular_functionmetal ion binding
C0070469cellular_componentrespirasome
C1901857biological_processpositive regulation of cellular respiration
D0002931biological_processresponse to ischemia
D0005739cellular_componentmitochondrion
D0005758cellular_componentmitochondrial intermembrane space
D0005829cellular_componentcytosol
D0006122biological_processmitochondrial electron transport, ubiquinol to cytochrome c
D0006123biological_processmitochondrial electron transport, cytochrome c to oxygen
D0006915biological_processapoptotic process
D0006979biological_processresponse to oxidative stress
D0009055molecular_functionelectron transfer activity
D0009629biological_processresponse to gravity
D0010730biological_processnegative regulation of hydrogen peroxide biosynthetic process
D0019899molecular_functionenzyme binding
D0020037molecular_functionheme binding
D0034349biological_processglial cell apoptotic process
D0034465biological_processresponse to carbon monoxide
D0042743biological_processhydrogen peroxide metabolic process
D0043293cellular_componentapoptosome
D0046688biological_processresponse to copper ion
D0046872molecular_functionmetal ion binding
D0070469cellular_componentrespirasome
D1901857biological_processpositive regulation of cellular respiration
Functional Information from PDB Data
site_idAC1
Number of Residues20
Detailsbinding site for residue HEC A 201
ChainResidue
ALYS13
ATYR48
ATHR49
AASN52
ATRP59
ATYR67
ATHR78
ALYS79
AMET80
AILE81
APHE82
ACYS14
AHOH318
ACYS17
AHIS18
AGLU28
AGLY29
APRO30
ATHR40
AGLY41

site_idAC2
Number of Residues8
Detailsbinding site for residue FC6 B 202
ChainResidue
ALYS87
ALYS88
AGLY89
AGLU90
BLYS87
BLYS88
BGLY89
BGLU90

site_idAC3
Number of Residues10
Detailsbinding site for residue FC6 B 203
ChainResidue
BASP2
BGLU4
BLYS8
BLYS39
BGLY56
BTHR58
BHOH329
BHOH373
DILE57
DTHR58

site_idAC4
Number of Residues7
Detailsbinding site for residue FC6 C 202
ChainResidue
CLYS87
CLYS88
CGLY89
DLYS87
DLYS88
DGLY89
DHOH364

site_idAC5
Number of Residues23
Detailsbinding site for Di-peptide HEC B 201 and CYS B 14
ChainResidue
BPHE10
BLYS13
BALA15
BGLN16
BCYS17
BHIS18
BGLU28
BGLY29
BPRO30
BTHR40
BGLY41
BTYR48
BTHR49
BASN52
BTRP59
BTYR67
BTHR78
BLYS79
BMET80
BILE81
BPHE82
BHOH302
BHOH315

site_idAC6
Number of Residues23
Detailsbinding site for Di-peptide HEC B 201 and CYS B 17
ChainResidue
BLYS13
BCYS14
BALA15
BGLN16
BHIS18
BLYS27
BGLU28
BGLY29
BPRO30
BTHR40
BGLY41
BTYR48
BTHR49
BASN52
BTRP59
BTYR67
BTHR78
BLYS79
BMET80
BILE81
BPHE82
BHOH302
BHOH315

site_idAC7
Number of Residues23
Detailsbinding site for Di-peptide HEC C 201 and CYS C 17
ChainResidue
CGLY29
CPRO30
CTHR40
CGLY41
CTYR48
CTHR49
CASN52
CTRP59
CTYR67
CTHR78
CLYS79
CMET80
CILE81
CPHE82
CHOH321
BILE81
CLYS13
CCYS14
CALA15
CGLN16
CHIS18
CLYS27
CGLU28

site_idAC8
Number of Residues22
Detailsbinding site for Di-peptide HEC C 201 and CYS C 14
ChainResidue
CPHE10
CLYS13
CALA15
CGLN16
CCYS17
CHIS18
CGLU28
CGLY29
CPRO30
CTHR40
CGLY41
CTYR48
CTHR49
CASN52
CTRP59
CTYR67
CTHR78
CLYS79
CMET80
CILE81
CPHE82
CHOH321

site_idAC9
Number of Residues23
Detailsbinding site for Di-peptide HEC D 201 and CYS D 17
ChainResidue
AILE81
DLYS13
DCYS14
DALA15
DGLN16
DHIS18
DLYS27
DGLU28
DGLY29
DPRO30
DTHR40
DGLY41
DTYR48
DTHR49
DASN52
DTRP59
DTYR67
DTHR78
DLYS79
DMET80
DILE81
DPHE82
DHOH314

site_idAD1
Number of Residues22
Detailsbinding site for Di-peptide HEC D 201 and CYS D 14
ChainResidue
DPHE10
DLYS13
DALA15
DGLN16
DCYS17
DHIS18
DGLU28
DGLY29
DPRO30
DTHR40
DGLY41
DTYR48
DTHR49
DASN52
DTRP59
DTYR67
DTHR78
DLYS79
DMET80
DILE81
DPHE82
DHOH314

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues8
DetailsBINDING: covalent
ChainResidueDetails
ACYS14
ACYS17
BCYS14
BCYS17
CCYS14
CCYS17
DCYS14
DCYS17

site_idSWS_FT_FI2
Number of Residues8
DetailsBINDING: axial binding residue
ChainResidueDetails
AHIS18
AMET80
BHIS18
BMET80
CHIS18
CMET80
DHIS18
DMET80

site_idSWS_FT_FI3
Number of Residues4
DetailsMOD_RES: N-acetylglycine => ECO:0000269|PubMed:191069
ChainResidueDetails
AGLY1
BGLY1
CGLY1
DGLY1

site_idSWS_FT_FI4
Number of Residues8
DetailsMOD_RES: Phosphotyrosine => ECO:0000250|UniProtKB:P62894
ChainResidueDetails
ATYR48
ATYR97
BTYR48
BTYR97
CTYR48
CTYR97
DTYR48
DTYR97

site_idSWS_FT_FI5
Number of Residues4
DetailsMOD_RES: N6-succinyllysine => ECO:0000250|UniProtKB:P62897
ChainResidueDetails
ALYS55
BLYS55
CLYS55
DLYS55

site_idSWS_FT_FI6
Number of Residues4
DetailsMOD_RES: N6-succinyllysine; alternate => ECO:0000250|UniProtKB:P62897
ChainResidueDetails
ALYS72
BLYS72
CLYS72
DLYS72

site_idSWS_FT_FI7
Number of Residues4
DetailsMOD_RES: N6-acetyllysine => ECO:0000250|UniProtKB:P62897
ChainResidueDetails
ALYS99
BLYS99
CLYS99
DLYS99

218853

PDB entries from 2024-04-24

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