5DDT

Crystal structure of IspD from Bacillus subtilis at 1.80 Angstroms resolution, crystal form I

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003824	molecular_function	catalytic activity
A	0008299	biological_process	isoprenoid biosynthetic process
A	0016779	molecular_function	nucleotidyltransferase activity
A	0019288	biological_process	isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway
A	0050518	molecular_function	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
A	0070567	molecular_function	cytidylyltransferase activity
B	0003824	molecular_function	catalytic activity
B	0008299	biological_process	isoprenoid biosynthetic process
B	0016779	molecular_function	nucleotidyltransferase activity
B	0019288	biological_process	isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway
B	0050518	molecular_function	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
B	0070567	molecular_function	cytidylyltransferase activity

Functional Information from PROSITE/UniProt

site_id	PS01295
Number of Residues	8
Details	ISPD 4-diphosphocytidyl-2C-methyl-D-erythritol synthase signature. VLVHDGAR

Chain	Residue	Details
A	VAL100-ARG107

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	SITE: Transition state stabilizer => ECO:0000250

Chain	Residue	Details
A	ARG15
A	LYS22
B	ARG15
B	LYS22

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site_id	SWS_FT_FI2
Number of Residues	4
Details	SITE: Positions MEP for the nucleophilic attack => ECO:0000250

Chain	Residue	Details
A	ARG152
A	LYS209
B	ARG152
B	LYS209

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