5DDK
Succinyl-CoA:acetate CoA-transferase (AarCH6-N347A) in complex with CoA
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003986 | molecular_function | acetyl-CoA hydrolase activity |
| A | 0006083 | biological_process | acetate metabolic process |
| A | 0006084 | biological_process | acetyl-CoA metabolic process |
| A | 0006085 | biological_process | acetyl-CoA biosynthetic process |
| A | 0008410 | molecular_function | CoA-transferase activity |
| A | 0008775 | molecular_function | acetate CoA-transferase activity |
| A | 0016740 | molecular_function | transferase activity |
| A | 0019427 | biological_process | acetyl-CoA biosynthetic process from acetate |
| A | 0045733 | biological_process | acetate catabolic process |
| A | 1901289 | biological_process | succinyl-CoA catabolic process |
| B | 0003986 | molecular_function | acetyl-CoA hydrolase activity |
| B | 0006083 | biological_process | acetate metabolic process |
| B | 0006084 | biological_process | acetyl-CoA metabolic process |
| B | 0006085 | biological_process | acetyl-CoA biosynthetic process |
| B | 0008410 | molecular_function | CoA-transferase activity |
| B | 0008775 | molecular_function | acetate CoA-transferase activity |
| B | 0016740 | molecular_function | transferase activity |
| B | 0019427 | biological_process | acetyl-CoA biosynthetic process from acetate |
| B | 0045733 | biological_process | acetate catabolic process |
| B | 1901289 | biological_process | succinyl-CoA catabolic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | binding site for residue CL A 601 |
| Chain | Residue |
| A | ASN112 |
| A | ARG120 |
| A | ASN125 |
| B | GLY443 |
| B | HOH970 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | binding site for residue CL A 602 |
| Chain | Residue |
| A | VAL196 |
| A | ARG354 |
| B | ARG354 |
| site_id | AC3 |
| Number of Residues | 35 |
| Details | binding site for residue COA A 603 |
| Chain | Residue |
| A | GLN267 |
| A | GLY269 |
| A | VAL270 |
| A | GLY271 |
| A | ASN272 |
| A | VAL273 |
| A | GLU294 |
| A | ASN361 |
| A | MET363 |
| A | ILE364 |
| A | SER374 |
| A | MET383 |
| A | ASN384 |
| A | GLY385 |
| A | ILE386 |
| A | GLY388 |
| A | SER389 |
| A | ALA407 |
| A | ILE412 |
| A | HOH708 |
| A | HOH724 |
| A | HOH756 |
| A | HOH779 |
| A | HOH783 |
| A | HOH787 |
| A | HOH799 |
| A | HOH804 |
| A | HOH821 |
| A | HOH890 |
| A | HOH900 |
| A | HOH913 |
| A | HOH926 |
| A | HOH936 |
| B | LYS240 |
| A | THR36 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | binding site for residue IMD A 604 |
| Chain | Residue |
| A | LEU486 |
| A | THR487 |
| B | THR487 |
| B | LEU490 |
| B | SER491 |
| B | GLN494 |
| B | HOH857 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | binding site for residue IMD A 605 |
| Chain | Residue |
| A | THR487 |
| A | LEU490 |
| A | SER491 |
| A | GLN494 |
| A | HOH835 |
| B | LEU486 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | binding site for residue IMD A 606 |
| Chain | Residue |
| A | MET418 |
| A | ALA419 |
| A | HOH733 |
| B | MET418 |
| B | ALA419 |
| B | HOH711 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | binding site for residue CL B 601 |
| Chain | Residue |
| A | GLY443 |
| A | HOH989 |
| B | ASN112 |
| B | ARG120 |
| B | ASN125 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | binding site for residue CL B 602 |
| Chain | Residue |
| B | VAL196 |
| B | ARG354 |
| B | HOH727 |
| site_id | AC9 |
| Number of Residues | 33 |
| Details | binding site for residue COA B 603 |
| Chain | Residue |
| B | HOH858 |
| B | HOH904 |
| B | HOH910 |
| B | HOH914 |
| B | GLN267 |
| B | VAL270 |
| B | GLY271 |
| B | ASN272 |
| B | VAL273 |
| B | GLU294 |
| B | ASN361 |
| B | MET363 |
| B | ILE364 |
| B | SER374 |
| B | ASN384 |
| B | GLY385 |
| B | ILE386 |
| B | SER389 |
| B | ALA407 |
| B | LYS408 |
| B | ILE412 |
| B | HOH708 |
| B | HOH715 |
| B | HOH746 |
| B | HOH750 |
| B | HOH754 |
| B | HOH766 |
| B | HOH774 |
| B | HOH783 |
| B | HOH797 |
| B | HOH820 |
| B | HOH854 |
| B | HOH856 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"5-glutamyl coenzyme A thioester intermediate","evidences":[{"source":"PubMed","id":"23030530","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 16 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"23030530","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
