Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 34 |
| Details | binding site for residue ANP A 401 |
| Chain | Residue |
| A | PHE4 |
| A | GLY117 |
| A | ASP118 |
| A | THR119 |
| A | MG403 |
| A | K406 |
| A | HOH522 |
| A | HOH528 |
| A | HOH572 |
| A | HOH577 |
| A | HOH603 |
| A | ILE7 |
| B | ASP43 |
| B | ASP71 |
| B | ARG143 |
| B | SER200 |
| B | ASP201 |
| B | TPS401 |
| B | MG402 |
| B | MG403 |
| B | K404 |
| B | MG406 |
| A | PHE11 |
| B | HOH539 |
| B | HOH541 |
| B | HOH553 |
| B | HOH577 |
| B | HOH607 |
| A | ILE23 |
| A | GLY24 |
| A | ASP25 |
| A | ASP26 |
| A | LEU84 |
| A | GLY116 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue MG A 402 |
| Chain | Residue |
| A | ASP201 |
| A | TPS408 |
| B | ANP405 |
| B | HOH511 |
| B | HOH562 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue MG A 403 |
| Chain | Residue |
| A | ASP118 |
| A | ANP401 |
| A | HOH528 |
| B | ASP43 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue K A 404 |
| Chain | Residue |
| A | ASP71 |
| A | HOH549 |
| A | HOH584 |
| A | HOH678 |
| B | ASP26 |
| B | ANP405 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | binding site for residue K A 405 |
| Chain | Residue |
| A | ALA74 |
| A | MET75 |
| A | VAL141 |
| A | MET196 |
| B | ASP25 |
| B | ASP26 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | binding site for residue K A 406 |
| Chain | Residue |
| A | GLU3 |
| A | ASP118 |
| A | THR119 |
| A | ANP401 |
| A | HOH572 |
| B | TPS401 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 407 |
| Chain | Residue |
| A | GLY156 |
| A | GLN157 |
| A | ARG175 |
| A | ARG182 |
| A | HOH639 |
| site_id | AC8 |
| Number of Residues | 21 |
| Details | binding site for residue TPS A 408 |
| Chain | Residue |
| A | GLY48 |
| A | ARG49 |
| A | HIS50 |
| A | PHE51 |
| A | PRO52 |
| A | LEU165 |
| A | LEU176 |
| A | SER200 |
| A | ASP201 |
| A | GLY246 |
| A | ASP248 |
| A | TYR301 |
| A | HIS303 |
| A | MG402 |
| A | HOH509 |
| A | HOH526 |
| A | HOH533 |
| B | THR120 |
| B | ANP405 |
| B | K408 |
| B | HOH562 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | binding site for residue MG A 409 |
| Chain | Residue |
| A | ASP43 |
| A | ASP71 |
| A | HOH582 |
| B | ANP405 |
| B | HOH572 |
| site_id | AD1 |
| Number of Residues | 6 |
| Details | binding site for residue MG A 410 |
| Chain | Residue |
| A | ASP71 |
| A | ASP198 |
| A | HOH626 |
| B | ASP26 |
| B | ANP405 |
| B | HOH572 |
| site_id | AD2 |
| Number of Residues | 4 |
| Details | binding site for residue MG A 411 |
| Chain | Residue |
| A | HOH549 |
| B | ASP118 |
| B | ANP405 |
| A | ASP43 |
| site_id | AD3 |
| Number of Residues | 21 |
| Details | binding site for residue TPS B 401 |
| Chain | Residue |
| A | THR120 |
| A | ANP401 |
| A | K406 |
| A | HOH522 |
| A | HOH592 |
| B | GLY48 |
| B | ARG49 |
| B | HIS50 |
| B | PHE51 |
| B | PRO52 |
| B | LEU165 |
| B | LEU176 |
| B | SER200 |
| B | ASP201 |
| B | ASP248 |
| B | TYR301 |
| B | HIS303 |
| B | MG406 |
| B | HOH514 |
| B | HOH539 |
| B | HOH561 |
| site_id | AD4 |
| Number of Residues | 5 |
| Details | binding site for residue MG B 402 |
| Chain | Residue |
| A | ANP401 |
| B | ASP43 |
| B | ASP71 |
| B | HOH553 |
| B | HOH577 |
| site_id | AD5 |
| Number of Residues | 6 |
| Details | binding site for residue MG B 403 |
| Chain | Residue |
| A | ASP26 |
| A | ANP401 |
| B | ASP71 |
| B | ASP198 |
| B | HOH553 |
| B | HOH607 |
| site_id | AD6 |
| Number of Residues | 6 |
| Details | binding site for residue K B 404 |
| Chain | Residue |
| A | ASP26 |
| A | ANP401 |
| A | HOH528 |
| B | ASP71 |
| B | HOH620 |
| B | HOH657 |
| site_id | AD7 |
| Number of Residues | 34 |
| Details | binding site for residue ANP B 405 |
| Chain | Residue |
| A | ASP43 |
| A | ASP71 |
| A | ARG143 |
| A | SER200 |
| A | ASP201 |
| A | MG402 |
| A | K404 |
| A | TPS408 |
| A | MG409 |
| A | MG410 |
| A | MG411 |
| A | HOH533 |
| A | HOH549 |
| A | HOH558 |
| A | HOH582 |
| A | HOH626 |
| B | PHE4 |
| B | ILE7 |
| B | PHE11 |
| B | ILE23 |
| B | GLY24 |
| B | ASP25 |
| B | ASP26 |
| B | LEU84 |
| B | GLY116 |
| B | GLY117 |
| B | ASP118 |
| B | THR119 |
| B | K408 |
| B | HOH511 |
| B | HOH571 |
| B | HOH572 |
| B | HOH578 |
| B | HOH590 |
| site_id | AD8 |
| Number of Residues | 5 |
| Details | binding site for residue MG B 406 |
| Chain | Residue |
| A | ANP401 |
| A | HOH522 |
| A | HOH592 |
| B | ASP201 |
| B | TPS401 |
| site_id | AD9 |
| Number of Residues | 6 |
| Details | binding site for residue K B 407 |
| Chain | Residue |
| A | ASP25 |
| A | ASP26 |
| B | ALA74 |
| B | MET75 |
| B | VAL141 |
| B | MET196 |
| site_id | AE1 |
| Number of Residues | 6 |
| Details | binding site for residue K B 408 |
| Chain | Residue |
| A | TPS408 |
| B | GLU3 |
| B | ASP118 |
| B | THR119 |
| B | ANP405 |
| B | HOH571 |
| site_id | AE2 |
| Number of Residues | 3 |
| Details | binding site for residue EDO B 409 |
| Chain | Residue |
| B | GLY156 |
| B | ARG182 |
| B | HOH615 |
