5DCW
Iridoid synthase from Catharanthus roseus - ligand free structure
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0016099 | biological_process | monoterpenoid biosynthetic process |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016627 | molecular_function | oxidoreductase activity, acting on the CH-CH group of donors |
| A | 0016628 | molecular_function | oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor |
| A | 0042802 | molecular_function | identical protein binding |
| A | 0042803 | molecular_function | protein homodimerization activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 900 |
| Chain | Residue |
| A | LYS288 |
| A | GLU291 |
| A | GLU292 |
| A | HOH1150 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 901 |
| Chain | Residue |
| A | ASP250 |
| A | ASP252 |
| A | SER376 |
| A | CYS377 |
| A | HOH1026 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 902 |
| Chain | Residue |
| A | SER30 |
| A | HIS103 |
| A | GLN137 |
| A | ALA262 |
| A | LYS268 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | binding site for residue EDO A 903 |
| Chain | Residue |
| A | ALA338 |
| A | ALA339 |
| A | PHE340 |
| A | TRP341 |
| A | HOH1004 |
| A | HOH1069 |
| A | HOH1159 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | ACT_SITE: ACT_SITE => ECO:0000269|PubMed:26768532 |
| Chain | Residue | Details |
| A | LYS146 | |
| A | TYR178 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 7 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:26551396, ECO:0000269|PubMed:26768532, ECO:0000269|PubMed:26868105, ECO:0007744|PDB:5COB, ECO:0007744|PDB:5DBF, ECO:0007744|PDB:5DF1 |
| Chain | Residue | Details |
| A | THR38 | |
| A | ARG66 | |
| A | ASP84 | |
| A | SER108 | |
| A | GLN142 | |
| A | VAL204 | |
| A | SER211 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:26768532, ECO:0007744|PDB:5DBI |
| Chain | Residue | Details |
| A | LYS146 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:26768532, ECO:0000269|PubMed:26868105, ECO:0007744|PDB:5COB, ECO:0007744|PDB:5DBI |
| Chain | Residue | Details |
| A | TYR178 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:26768532, ECO:0000269|PubMed:26868105, ECO:0007744|PDB:5COB |
| Chain | Residue | Details |
| A | SER349 |
