5DCB
Neisseria meningitidis 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase regulated and complexed with PEP
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003849 | molecular_function | 3-deoxy-7-phosphoheptulonate synthase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0008652 | biological_process | amino acid biosynthetic process |
| A | 0009058 | biological_process | biosynthetic process |
| A | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
| A | 0009423 | biological_process | chorismate biosynthetic process |
| A | 0016740 | molecular_function | transferase activity |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0003849 | molecular_function | 3-deoxy-7-phosphoheptulonate synthase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0008652 | biological_process | amino acid biosynthetic process |
| B | 0009058 | biological_process | biosynthetic process |
| B | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
| B | 0009423 | biological_process | chorismate biosynthetic process |
| B | 0016740 | molecular_function | transferase activity |
| B | 0046872 | molecular_function | metal ion binding |
| C | 0003849 | molecular_function | 3-deoxy-7-phosphoheptulonate synthase activity |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0008652 | biological_process | amino acid biosynthetic process |
| C | 0009058 | biological_process | biosynthetic process |
| C | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
| C | 0009423 | biological_process | chorismate biosynthetic process |
| C | 0016740 | molecular_function | transferase activity |
| C | 0046872 | molecular_function | metal ion binding |
| D | 0003849 | molecular_function | 3-deoxy-7-phosphoheptulonate synthase activity |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0008652 | biological_process | amino acid biosynthetic process |
| D | 0009058 | biological_process | biosynthetic process |
| D | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
| D | 0009423 | biological_process | chorismate biosynthetic process |
| D | 0016740 | molecular_function | transferase activity |
| D | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | binding site for residue MN A 401 |
| Chain | Residue |
| A | CYS63 |
| A | HIS270 |
| A | GLU304 |
| A | ASP324 |
| A | HOH503 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 A 402 |
| Chain | Residue |
| A | SER206 |
| A | HIS207 |
| A | GLY226 |
| A | HOH502 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 404 |
| Chain | Residue |
| A | GLY193 |
| A | ASN194 |
| A | LEU195 |
| A | LYS196 |
| A | HOH551 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | binding site for residue PEG A 405 |
| Chain | Residue |
| A | ASP112 |
| A | LEU115 |
| A | ASP313 |
| site_id | AC5 |
| Number of Residues | 16 |
| Details | binding site for residue PGE A 406 |
| Chain | Residue |
| A | GLN172 |
| A | ARG175 |
| A | ALA204 |
| A | HIS207 |
| A | SER208 |
| A | HIS209 |
| A | HOH509 |
| A | HOH541 |
| A | HOH643 |
| A | HOH645 |
| B | ARG101 |
| B | THR102 |
| B | THR103 |
| B | VAL104 |
| B | LYS107 |
| B | HOH534 |
| site_id | AC6 |
| Number of Residues | 11 |
| Details | binding site for residue PEP A 407 |
| Chain | Residue |
| A | ARG94 |
| A | TYR96 |
| A | LYS99 |
| A | GLU145 |
| A | LYS188 |
| A | ARG236 |
| A | HIS270 |
| A | HOH503 |
| A | HOH548 |
| A | HOH562 |
| A | HOH604 |
| site_id | AC7 |
| Number of Residues | 12 |
| Details | binding site for residue PHE A 408 |
| Chain | Residue |
| A | MET149 |
| A | GLN153 |
| A | ALA156 |
| A | GLY180 |
| A | LEU181 |
| A | SER182 |
| A | PHE211 |
| A | SER213 |
| A | LYS216 |
| B | ASP8 |
| B | ASP9 |
| B | HOH623 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | binding site for residue CL A 409 |
| Chain | Residue |
| A | THR215 |
| A | LYS216 |
| B | HOH592 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | binding site for residue MN B 401 |
| Chain | Residue |
| B | CYS63 |
| B | HIS270 |
| B | GLU304 |
| B | ASP324 |
| B | HOH528 |
| site_id | AD1 |
| Number of Residues | 3 |
| Details | binding site for residue EDO B 402 |
| Chain | Residue |
| B | TRP106 |
| B | ASP112 |
| B | LEU115 |
| site_id | AD2 |
| Number of Residues | 12 |
| Details | binding site for residue PEP B 403 |
| Chain | Residue |
| B | ARG94 |
| B | TYR96 |
| B | LYS99 |
| B | GLU145 |
| B | LYS188 |
| B | ARG236 |
| B | HIS270 |
| B | HOH513 |
| B | HOH515 |
| B | HOH528 |
| B | HOH612 |
| B | HOH621 |
| site_id | AD3 |
| Number of Residues | 12 |
| Details | binding site for residue PHE B 404 |
| Chain | Residue |
| A | ASP8 |
| A | ASP9 |
| A | HOH516 |
| B | MET149 |
| B | GLN153 |
| B | ALA156 |
| B | GLY180 |
| B | LEU181 |
| B | SER182 |
| B | PHE211 |
| B | SER213 |
| B | VAL223 |
| site_id | AD4 |
| Number of Residues | 4 |
| Details | binding site for residue CL B 405 |
| Chain | Residue |
| A | HOH708 |
| B | THR215 |
| B | LYS216 |
| B | HOH671 |
| site_id | AD5 |
| Number of Residues | 6 |
| Details | binding site for residue MN C 401 |
| Chain | Residue |
| C | ASP324 |
| C | HOH503 |
| C | CYS63 |
| C | ARG94 |
| C | HIS270 |
| C | GLU304 |
| site_id | AD6 |
| Number of Residues | 11 |
| Details | binding site for residue PEP C 402 |
| Chain | Residue |
| C | ARG94 |
| C | TYR96 |
| C | LYS99 |
| C | GLU145 |
| C | LYS188 |
| C | ARG236 |
| C | HIS270 |
| C | HOH502 |
| C | HOH503 |
| C | HOH532 |
| C | HOH562 |
| site_id | AD7 |
| Number of Residues | 13 |
| Details | binding site for residue PHE C 403 |
| Chain | Residue |
| C | MET149 |
| C | GLN153 |
| C | ALA156 |
| C | GLY180 |
| C | LEU181 |
| C | SER182 |
| C | PHE211 |
| C | SER213 |
| C | LYS216 |
| C | VAL223 |
| C | HOH540 |
| D | ASP8 |
| D | ASP9 |
| site_id | AD8 |
| Number of Residues | 5 |
| Details | binding site for residue MN D 401 |
| Chain | Residue |
| D | CYS63 |
| D | HIS270 |
| D | GLU304 |
| D | ASP324 |
| D | HOH569 |
| site_id | AD9 |
| Number of Residues | 4 |
| Details | binding site for residue PEG D 403 |
| Chain | Residue |
| D | TRP106 |
| D | ASP112 |
| D | LEU115 |
| D | HOH568 |
| site_id | AE1 |
| Number of Residues | 13 |
| Details | binding site for residue PEP D 404 |
| Chain | Residue |
| D | ARG94 |
| D | TYR96 |
| D | LYS99 |
| D | GLU145 |
| D | LYS188 |
| D | ARG236 |
| D | HIS270 |
| D | MET302 |
| D | HOH509 |
| D | HOH549 |
| D | HOH569 |
| D | HOH615 |
| D | HOH617 |
| site_id | AE2 |
| Number of Residues | 12 |
| Details | binding site for residue PHE D 405 |
| Chain | Residue |
| C | ASP8 |
| C | ASP9 |
| C | HOH535 |
| D | GLN153 |
| D | ALA156 |
| D | GLY180 |
| D | LEU181 |
| D | SER182 |
| D | PHE211 |
| D | SER213 |
| D | LYS216 |
| D | VAL223 |
| site_id | AE3 |
| Number of Residues | 2 |
| Details | binding site for residue CL D 406 |
| Chain | Residue |
| A | HIS219 |
| D | HIS219 |
