5DC0

CRYSTAL STRUCTURE OF MONOBODY GG3/ABL1 SH2 DOMAIN COMPLEX

Functional Information from GO Data

Chain	GOid	namespace	contents
B	0004713	molecular_function	protein tyrosine kinase activity

Functional Information from PROSITE/UniProt

site_id	PS00687
Number of Residues	8
Details	ALDEHYDE_DEHYDR_GLU Aldehyde dehydrogenases glutamic acid active site. GETGGNSP

Chain	Residue	Details
A	GLY37-PRO44

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	BINDING:

Chain	Residue	Details
B	SER248

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site_id	SWS_FT_FI2
Number of Residues	4
Details	MOD_RES: Phosphotyrosine => ECO:0000269|PubMed:16912036

Chain	Residue	Details
B	ASN139
B	GLU172
B	ARG185
B	ALA215

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site_id	SWS_FT_FI3
Number of Residues	1
Details	MOD_RES: Phosphotyrosine; by autocatalysis => ECO:0000269|PubMed:16912036

Chain	Residue	Details
B	ASP226

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site_id	SWS_FT_FI4
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:P42684

Chain	Residue	Details
B	ILE229

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