5DB2

Menin in complex with MI-389

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005634	cellular_component	nucleus

Functional Information from PDB Data

site_id	AC1
Number of Residues	20
Details	binding site for residue 58R A 601

Chain	Residue
A	SER155
A	TYR319
A	MET322
A	TYR323
A	GLY326
A	TRP341
A	GLU363
A	GLU366
A	DMS602
A	HOH909
A	HOH1022
A	LEU177
A	HOH1051
A	SER178
A	ASP180
A	HIS181
A	ALA182
A	PHE238
A	TYR276
A	MET278

---

site_id	AC2
Number of Residues	4
Details	binding site for residue DMS A 602

Chain	Residue
A	SER155
A	58R601
A	HOH942
A	HOH965

---

site_id	AC3
Number of Residues	7
Details	binding site for residue PG4 A 603

Chain	Residue
A	LEU75
A	THR76
A	TYR361
A	PHE365
A	HOH706
A	HOH800
A	HOH962

---

site_id	AC4
Number of Residues	2
Details	binding site for residue SO4 A 604

Chain	Residue
A	ARG14
A	HOH920

---

site_id	AC5
Number of Residues	3
Details	binding site for residue SO4 A 605

Chain	Residue
A	TYR133
A	PHE134
A	ARG137

---

site_id	AC6
Number of Residues	6
Details	binding site for residue SO4 A 606

Chain	Residue
A	ARG332
A	VAL334
A	ARG335
A	GLY401
A	ALA403
A	HOH831

---

site_id	AC7
Number of Residues	1
Details	binding site for residue SO4 A 607

Chain	Residue
A	ARG21

---

site_id	AC8
Number of Residues	2
Details	binding site for residue SO4 A 608

Chain	Residue
A	ARG446
A	HOH738

---

site_id	AC9
Number of Residues	6
Details	binding site for residue DMS A 609

Chain	Residue
A	PHE43
A	PHE47
A	GLY386
A	GLN400
A	HOH973
A	HOH1040

---

site_id	AD1
Number of Residues	6
Details	binding site for residue DMS A 610

Chain	Residue
A	VAL185
A	GLY190
A	GLU191
A	TYR227
A	ARG229
A	SER583

---

site_id	AD2
Number of Residues	2
Details	binding site for residue PEG A 611

Chain	Residue
A	LYS135
A	TRP198

---