Functional Information from GO Data
Chain | GOid | namespace | contents |
B | 0000287 | molecular_function | magnesium ion binding |
B | 0003824 | molecular_function | catalytic activity |
B | 0003984 | molecular_function | acetolactate synthase activity |
B | 0016740 | molecular_function | transferase activity |
B | 0019752 | biological_process | carboxylic acid metabolic process |
B | 0030976 | molecular_function | thiamine pyrophosphate binding |
B | 0034077 | biological_process | butanediol metabolic process |
B | 0046872 | molecular_function | metal ion binding |
M | 0000287 | molecular_function | magnesium ion binding |
M | 0003824 | molecular_function | catalytic activity |
M | 0003984 | molecular_function | acetolactate synthase activity |
M | 0016740 | molecular_function | transferase activity |
M | 0019752 | biological_process | carboxylic acid metabolic process |
M | 0030976 | molecular_function | thiamine pyrophosphate binding |
M | 0034077 | biological_process | butanediol metabolic process |
M | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 5 |
Details | binding site for residue MG B 601 |
Chain | Residue |
B | ASP447 |
B | ASP474 |
B | GLY476 |
B | EN0605 |
B | HOH705 |
site_id | AC2 |
Number of Residues | 4 |
Details | binding site for residue MG B 602 |
Chain | Residue |
B | SER129 |
B | THR132 |
B | HOH776 |
B | HOH816 |
site_id | AC3 |
Number of Residues | 5 |
Details | binding site for residue MG B 603 |
Chain | Residue |
B | ARG69 |
B | GLN220 |
B | PRO221 |
B | HOH747 |
B | HOH784 |
site_id | AC4 |
Number of Residues | 10 |
Details | binding site for residue PO4 B 604 |
Chain | Residue |
B | PHE256 |
B | GLY258 |
B | ARG259 |
B | GLN266 |
B | ARG352 |
B | ALA402 |
B | ARG403 |
B | LEU405 |
B | TYR406 |
B | HOH708 |
site_id | AC5 |
Number of Residues | 27 |
Details | binding site for residue EN0 B 605 |
Chain | Residue |
B | PRO33 |
B | ALA35 |
B | GLU57 |
B | PRO83 |
B | ASN87 |
B | GLN120 |
B | MET394 |
B | GLY395 |
B | SER396 |
B | PHE397 |
B | GLN420 |
B | MET422 |
B | GLY446 |
B | ASP447 |
B | GLY448 |
B | GLY449 |
B | ASP474 |
B | GLY476 |
B | TYR477 |
B | ASN478 |
B | MET479 |
B | VAL480 |
B | TYR543 |
B | MG601 |
B | HOH705 |
B | HOH715 |
B | HOH761 |
site_id | AC6 |
Number of Residues | 5 |
Details | binding site for residue MG M 601 |
Chain | Residue |
M | ASP447 |
M | ASP474 |
M | GLY476 |
M | EN0604 |
M | HOH708 |
site_id | AC7 |
Number of Residues | 4 |
Details | binding site for residue MG M 602 |
Chain | Residue |
M | SER129 |
M | THR132 |
M | HOH733 |
M | HOH833 |
site_id | AC8 |
Number of Residues | 7 |
Details | binding site for residue PO4 M 603 |
Chain | Residue |
M | GLY258 |
M | ARG259 |
M | GLN266 |
M | ARG352 |
M | LEU405 |
M | TYR406 |
M | HOH711 |
site_id | AC9 |
Number of Residues | 26 |
Details | binding site for residue EN0 M 604 |
Chain | Residue |
M | PRO33 |
M | ALA35 |
M | GLU57 |
M | THR80 |
M | ASN87 |
M | MET394 |
M | GLY395 |
M | SER396 |
M | PHE397 |
M | GLN420 |
M | MET422 |
M | GLY446 |
M | ASP447 |
M | GLY448 |
M | GLY449 |
M | ASP474 |
M | GLY476 |
M | TYR477 |
M | ASN478 |
M | MET479 |
M | VAL480 |
M | GLN483 |
M | TYR543 |
M | MG601 |
M | HOH708 |
M | HOH731 |
Functional Information from PROSITE/UniProt
site_id | PS00187 |
Number of Residues | 20 |
Details | TPP_ENZYMES Thiamine pyrophosphate enzymes signature. IGawlvnPerkvVsVsGDGG |
Chain | Residue | Details |
B | ILE430-GLY449 | |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 8 |
Details | BINDING: BINDING => ECO:0000250 |
Chain | Residue | Details |
B | ARG159 | |
B | PHE263 | |
B | ASP304 | |
B | ASP447 | |
M | ARG159 | |
M | PHE263 | |
M | ASP304 | |
M | ASP447 | |
Catalytic Information from CSA
site_id | MCSA1 |
Number of Residues | 5 |
Details | M-CSA 722 |
Chain | Residue | Details |
B | MET394 | electrostatic stabiliser |
B | MET422 | steric role |
B | ASP447 | metal ligand |
B | ASP474 | metal ligand |
B | GLY476 | metal ligand |
site_id | MCSA2 |
Number of Residues | 5 |
Details | M-CSA 722 |
Chain | Residue | Details |
M | MET394 | electrostatic stabiliser |
M | MET422 | steric role |
M | ASP447 | metal ligand |
M | ASP474 | metal ligand |
M | GLY476 | metal ligand |