5D5U

Crystal structure of human Hsf1 with HSE DNA

Functional Information from GO Data

Chain	GOid	namespace	contents
B	0003700	molecular_function	DNA-binding transcription factor activity
B	0006355	biological_process	regulation of DNA-templated transcription
B	0043565	molecular_function	sequence-specific DNA binding

Functional Information from PROSITE/UniProt

site_id	PS00434
Number of Residues	25
Details	HSF_DOMAIN HSF-type DNA-binding domain signature. LpkyFKHnNmASFVRQLNmYgFRKV

Chain	Residue	Details
B	LEU57-VAL81

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"19229036","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"24581496","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	1
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"24581496","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26754925","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---