5D4V
HcgC with SAH and a guanylylpyridinol (GP) derivative
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0008168 | molecular_function | methyltransferase activity |
| A | 0016740 | molecular_function | transferase activity |
| A | 0032259 | biological_process | methylation |
| A | 0160300 | biological_process | iron-guanylylpyridinol cofactor biosynthetic process |
| A | 0160302 | molecular_function | 6-carboxymethyl-5-methyl-4-hydroxypyridin-2-ol 3-C-methyltransferase activity |
| A | 1904047 | molecular_function | S-adenosyl-L-methionine binding |
| B | 0008168 | molecular_function | methyltransferase activity |
| B | 0016740 | molecular_function | transferase activity |
| B | 0032259 | biological_process | methylation |
| B | 0160300 | biological_process | iron-guanylylpyridinol cofactor biosynthetic process |
| B | 0160302 | molecular_function | 6-carboxymethyl-5-methyl-4-hydroxypyridin-2-ol 3-C-methyltransferase activity |
| B | 1904047 | molecular_function | S-adenosyl-L-methionine binding |
| C | 0008168 | molecular_function | methyltransferase activity |
| C | 0016740 | molecular_function | transferase activity |
| C | 0032259 | biological_process | methylation |
| C | 0160300 | biological_process | iron-guanylylpyridinol cofactor biosynthetic process |
| C | 0160302 | molecular_function | 6-carboxymethyl-5-methyl-4-hydroxypyridin-2-ol 3-C-methyltransferase activity |
| C | 1904047 | molecular_function | S-adenosyl-L-methionine binding |
| D | 0008168 | molecular_function | methyltransferase activity |
| D | 0016740 | molecular_function | transferase activity |
| D | 0032259 | biological_process | methylation |
| D | 0160300 | biological_process | iron-guanylylpyridinol cofactor biosynthetic process |
| D | 0160302 | molecular_function | 6-carboxymethyl-5-methyl-4-hydroxypyridin-2-ol 3-C-methyltransferase activity |
| D | 1904047 | molecular_function | S-adenosyl-L-methionine binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 21 |
| Details | binding site for residue SAH A 301 |
| Chain | Residue |
| A | LYS34 |
| A | MET82 |
| A | LEU117 |
| A | THR118 |
| A | ILE123 |
| A | GLU139 |
| A | GLY184 |
| A | THR185 |
| A | HOH433 |
| A | HOH533 |
| A | HOH544 |
| A | GLY54 |
| A | HOH557 |
| C | HOH430 |
| A | VAL55 |
| A | TYR56 |
| A | LEU57 |
| A | TRP58 |
| A | ASP77 |
| A | ILE78 |
| A | HIS79 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 A 302 |
| Chain | Residue |
| A | HIS79 |
| A | GLU80 |
| A | PHE81 |
| A | HOH431 |
| A | HOH554 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | binding site for residue SO4 A 303 |
| Chain | Residue |
| A | ARG214 |
| A | SER231 |
| A | GLU232 |
| A | HOH412 |
| A | HOH422 |
| A | HOH435 |
| A | HOH444 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 A 304 |
| Chain | Residue |
| A | TYR35 |
| A | ARG39 |
| A | LYS68 |
| A | TYR69 |
| site_id | AC5 |
| Number of Residues | 19 |
| Details | binding site for residue SAH B 301 |
| Chain | Residue |
| B | LYS34 |
| B | GLY54 |
| B | VAL55 |
| B | TYR56 |
| B | LEU57 |
| B | TRP58 |
| B | ASP77 |
| B | ILE78 |
| B | HIS79 |
| B | MET82 |
| B | LEU117 |
| B | THR118 |
| B | ILE123 |
| B | GLU139 |
| B | GLY184 |
| B | THR185 |
| B | HOH474 |
| B | HOH506 |
| B | HOH545 |
| site_id | AC6 |
| Number of Residues | 10 |
| Details | binding site for residue SO4 B 302 |
| Chain | Residue |
| A | TYR150 |
| A | HOH423 |
| A | HOH445 |
| B | ASP140 |
| B | LYS142 |
| B | TYR156 |
| B | LYS172 |
| B | YGP307 |
| B | HOH446 |
| B | HOH516 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 B 303 |
| Chain | Residue |
| B | HIS79 |
| B | GLU80 |
| B | PHE81 |
| site_id | AC8 |
| Number of Residues | 7 |
| Details | binding site for residue SO4 B 304 |
| Chain | Residue |
| B | TYR56 |
| B | GLY184 |
| B | MET186 |
| B | THR187 |
| B | GLU217 |
| B | HOH474 |
| B | HOH545 |
| site_id | AC9 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 B 305 |
| Chain | Residue |
| B | ARG22 |
| B | HOH534 |
| B | HOH556 |
| site_id | AD1 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 B 306 |
| Chain | Residue |
| B | ASP225 |
| B | HIS227 |
| B | LYS228 |
| site_id | AD2 |
| Number of Residues | 11 |
| Details | binding site for residue YGP B 307 |
| Chain | Residue |
| A | TYR156 |
| A | LYS172 |
| A | GLU266 |
| A | HOH423 |
| B | TYR156 |
| B | LYS157 |
| B | ALA160 |
| B | GLU266 |
| B | SO4302 |
| B | HOH424 |
| B | HOH516 |
| site_id | AD3 |
| Number of Residues | 21 |
| Details | binding site for residue SAH C 301 |
| Chain | Residue |
| C | ASP77 |
| C | ILE78 |
| C | HIS79 |
| C | MET82 |
| C | LEU117 |
| C | THR118 |
| C | ILE123 |
| C | GLU139 |
| C | GLY184 |
| C | THR185 |
| C | HOH447 |
| C | HOH452 |
| C | HOH480 |
| C | HOH514 |
| C | HOH560 |
| C | LYS34 |
| C | GLY54 |
| C | VAL55 |
| C | TYR56 |
| C | LEU57 |
| C | TRP58 |
| site_id | AD4 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 C 302 |
| Chain | Residue |
| C | ILE78 |
| C | HIS79 |
| C | GLU80 |
| C | PHE81 |
| site_id | AD5 |
| Number of Residues | 8 |
| Details | binding site for residue SO4 C 303 |
| Chain | Residue |
| A | HOH513 |
| C | TYR56 |
| C | GLY184 |
| C | MET186 |
| C | THR187 |
| C | HOH415 |
| C | HOH452 |
| C | HOH560 |
| site_id | AD6 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 C 304 |
| Chain | Residue |
| C | ARG214 |
| C | SER231 |
| C | GLU232 |
| C | HOH413 |
| C | HOH420 |
| C | HOH507 |
| site_id | AD7 |
| Number of Residues | 9 |
| Details | binding site for residue SO4 C 305 |
| Chain | Residue |
| C | ASP140 |
| C | LYS142 |
| C | TYR156 |
| C | LYS172 |
| C | YGP308 |
| C | HOH422 |
| C | HOH432 |
| C | HOH556 |
| D | HOH552 |
| site_id | AD8 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 C 306 |
| Chain | Residue |
| C | ARG22 |
| C | HOH484 |
| site_id | AD9 |
| Number of Residues | 1 |
| Details | binding site for residue SO4 C 307 |
| Chain | Residue |
| C | HIS227 |
| site_id | AE1 |
| Number of Residues | 12 |
| Details | binding site for residue YGP C 308 |
| Chain | Residue |
| C | TYR156 |
| C | LYS157 |
| C | ALA160 |
| C | GLU266 |
| C | SO4305 |
| C | HOH406 |
| C | HOH428 |
| C | HOH565 |
| D | TYR156 |
| D | LYS172 |
| D | GLU266 |
| D | HOH552 |
| site_id | AE2 |
| Number of Residues | 20 |
| Details | binding site for residue SAH D 301 |
| Chain | Residue |
| D | LYS34 |
| D | GLY54 |
| D | VAL55 |
| D | TYR56 |
| D | LEU57 |
| D | TRP58 |
| D | ASP77 |
| D | ILE78 |
| D | HIS79 |
| D | MET82 |
| D | LEU97 |
| D | LEU117 |
| D | THR118 |
| D | ILE123 |
| D | GLU139 |
| D | GLY184 |
| D | THR185 |
| D | HOH453 |
| D | HOH476 |
| D | HOH530 |
| site_id | AE3 |
| Number of Residues | 7 |
| Details | binding site for residue SO4 D 302 |
| Chain | Residue |
| D | LYS72 |
| D | TYR74 |
| D | LYS93 |
| D | LYS103 |
| D | HOH424 |
| D | HOH443 |
| D | HOH546 |
| site_id | AE4 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 D 303 |
| Chain | Residue |
| D | TYR35 |
| D | ARG39 |
| D | MET65 |
| D | LYS68 |
| D | TYR69 |
| D | HOH481 |
| site_id | AE5 |
| Number of Residues | 8 |
| Details | binding site for residue SO4 D 304 |
| Chain | Residue |
| B | HOH477 |
| D | TYR56 |
| D | GLY184 |
| D | MET186 |
| D | THR187 |
| D | HOH404 |
| D | HOH425 |
| D | HOH476 |
| site_id | AE6 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 D 305 |
| Chain | Residue |
| D | HIS79 |
| D | GLU80 |
| D | PHE81 |
| D | HOH457 |
| D | HOH501 |
