5D1W

Crystal structure of Mycobacterium tuberculosis Rv3249c transcriptional regulator.

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000976	molecular_function	transcription cis-regulatory region binding
A	0003677	molecular_function	DNA binding
A	0003700	molecular_function	DNA-binding transcription factor activity
A	0005737	cellular_component	cytoplasm
A	0006355	biological_process	regulation of DNA-templated transcription
B	0000976	molecular_function	transcription cis-regulatory region binding
B	0003677	molecular_function	DNA binding
B	0003700	molecular_function	DNA-binding transcription factor activity
B	0005737	cellular_component	cytoplasm
B	0006355	biological_process	regulation of DNA-templated transcription
C	0000976	molecular_function	transcription cis-regulatory region binding
C	0003677	molecular_function	DNA binding
C	0003700	molecular_function	DNA-binding transcription factor activity
C	0005737	cellular_component	cytoplasm
C	0006355	biological_process	regulation of DNA-templated transcription
D	0000976	molecular_function	transcription cis-regulatory region binding
D	0003677	molecular_function	DNA binding
D	0003700	molecular_function	DNA-binding transcription factor activity
D	0005737	cellular_component	cytoplasm
D	0006355	biological_process	regulation of DNA-templated transcription
E	0000976	molecular_function	transcription cis-regulatory region binding
E	0003677	molecular_function	DNA binding
E	0003700	molecular_function	DNA-binding transcription factor activity
E	0005737	cellular_component	cytoplasm
E	0006355	biological_process	regulation of DNA-templated transcription
F	0000976	molecular_function	transcription cis-regulatory region binding
F	0003677	molecular_function	DNA binding
F	0003700	molecular_function	DNA-binding transcription factor activity
F	0005737	cellular_component	cytoplasm
F	0006355	biological_process	regulation of DNA-templated transcription

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue PLM A 301

Chain	Residue
A	VAL86
A	PHE101
A	GLY104
A	PHE105

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site_id	AC2
Number of Residues	6
Details	binding site for residue PLM B 301

Chain	Residue
B	VAL173
B	VAL86
B	PHE101
B	GLY104
B	PHE105
B	PHE108

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site_id	AC3
Number of Residues	11
Details	binding site for residue PLM C 301

Chain	Residue
C	LEU78
C	ALA79
C	VAL86
C	GLY104
C	PHE105
C	PHE108
C	VAL118
C	ILE141
C	ILE172
C	VAL173
C	LEU177

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site_id	AC4
Number of Residues	5
Details	binding site for residue PLM D 301

Chain	Residue
D	ALA75
D	VAL86
D	GLY104
D	PHE105
D	LEU117

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	114
Details	DNA_BIND: H-T-H motif => ECO:0000255|PROSITE-ProRule:PRU00335

Chain	Residue	Details
A	THR45-PHE64
B	THR45-PHE64
C	THR45-PHE64
D	THR45-PHE64
E	THR45-PHE64
F	THR45-PHE64

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