5D1R
Crystal structure of Mycobacterium tuberculosis Rv1816 transcriptional regulator.
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000976 | molecular_function | transcription cis-regulatory region binding |
| A | 0003677 | molecular_function | DNA binding |
| A | 0003700 | molecular_function | DNA-binding transcription factor activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006351 | biological_process | DNA-templated transcription |
| A | 0006355 | biological_process | regulation of DNA-templated transcription |
| B | 0000976 | molecular_function | transcription cis-regulatory region binding |
| B | 0003677 | molecular_function | DNA binding |
| B | 0003700 | molecular_function | DNA-binding transcription factor activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0006351 | biological_process | DNA-templated transcription |
| B | 0006355 | biological_process | regulation of DNA-templated transcription |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | binding site for residue NI A 301 |
| Chain | Residue |
| A | HIS236 |
| A | HIS238 |
| B | HIS234 |
| B | HIS239 |
| B | HOH449 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue NI A 302 |
| Chain | Residue |
| B | HOH476 |
| B | HOH486 |
| A | HIS235 |
| A | HIS237 |
| B | HIS238 |
| B | HOH444 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 A 303 |
| Chain | Residue |
| A | HIS237 |
| A | HIS238 |
| A | HIS239 |
| A | HOH410 |
| A | HOH457 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue MG A 304 |
| Chain | Residue |
| A | ASN109 |
| A | PRO110 |
| A | ALA111 |
| A | ARG112 |
| A | HOH475 |
| A | HOH506 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | binding site for residue 56S A 305 |
| Chain | Residue |
| A | THR136 |
| A | VAL139 |
| A | PHE142 |
| A | CYS189 |
| A | PHE190 |
| B | TYR208 |
| B | ALA210 |
| site_id | AC6 |
| Number of Residues | 9 |
| Details | binding site for residue SO4 B 301 |
| Chain | Residue |
| A | LEU226 |
| B | ARG184 |
| B | LYS188 |
| B | GLU233 |
| B | HIS234 |
| B | HIS235 |
| B | HIS236 |
| B | HOH412 |
| B | HOH426 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 B 302 |
| Chain | Residue |
| B | HIS235 |
| B | HIS236 |
| B | HIS237 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | binding site for residue MG B 303 |
| Chain | Residue |
| B | LEU30 |
| B | ASN109 |
| B | ALA111 |
| B | ARG112 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 120 |
| Details | Domain: {"description":"HTH tetR-type","evidences":[{"source":"PROSITE-ProRule","id":"PRU00335","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 38 |
| Details | DNA binding: {"description":"H-T-H motif","evidences":[{"source":"PROSITE-ProRule","id":"PRU00335","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
