5D05
Neisseria meningitidis 3 deoxy-D-arabino-heptulosonate 7-phosphate synthase Lys107Ala variant regulated
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0003849 | molecular_function | 3-deoxy-7-phosphoheptulonate synthase activity |
A | 0005737 | cellular_component | cytoplasm |
A | 0008652 | biological_process | amino acid biosynthetic process |
A | 0009058 | biological_process | biosynthetic process |
A | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
A | 0009423 | biological_process | chorismate biosynthetic process |
A | 0016740 | molecular_function | transferase activity |
A | 0046872 | molecular_function | metal ion binding |
B | 0003849 | molecular_function | 3-deoxy-7-phosphoheptulonate synthase activity |
B | 0005737 | cellular_component | cytoplasm |
B | 0008652 | biological_process | amino acid biosynthetic process |
B | 0009058 | biological_process | biosynthetic process |
B | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
B | 0009423 | biological_process | chorismate biosynthetic process |
B | 0016740 | molecular_function | transferase activity |
B | 0046872 | molecular_function | metal ion binding |
C | 0003849 | molecular_function | 3-deoxy-7-phosphoheptulonate synthase activity |
C | 0005737 | cellular_component | cytoplasm |
C | 0008652 | biological_process | amino acid biosynthetic process |
C | 0009058 | biological_process | biosynthetic process |
C | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
C | 0009423 | biological_process | chorismate biosynthetic process |
C | 0016740 | molecular_function | transferase activity |
C | 0046872 | molecular_function | metal ion binding |
D | 0003849 | molecular_function | 3-deoxy-7-phosphoheptulonate synthase activity |
D | 0005737 | cellular_component | cytoplasm |
D | 0008652 | biological_process | amino acid biosynthetic process |
D | 0009058 | biological_process | biosynthetic process |
D | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
D | 0009423 | biological_process | chorismate biosynthetic process |
D | 0016740 | molecular_function | transferase activity |
D | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 5 |
Details | binding site for residue MN A 401 |
Chain | Residue |
A | CYS63 |
A | HIS270 |
A | GLU304 |
A | ASP324 |
A | HOH521 |
site_id | AC2 |
Number of Residues | 1 |
Details | binding site for residue CL A 402 |
Chain | Residue |
A | LYS216 |
site_id | AC3 |
Number of Residues | 11 |
Details | binding site for residue PEP A 403 |
Chain | Residue |
A | ARG236 |
A | HIS270 |
A | HOH512 |
A | HOH521 |
A | HOH546 |
A | HOH652 |
A | HOH653 |
A | HOH694 |
A | ARG94 |
A | GLU145 |
A | LYS188 |
site_id | AC4 |
Number of Residues | 1 |
Details | binding site for residue SO4 A 404 |
Chain | Residue |
A | TYR26 |
site_id | AC5 |
Number of Residues | 5 |
Details | binding site for residue PGE A 405 |
Chain | Residue |
A | LEU115 |
A | ASP116 |
A | GLY117 |
A | ASP313 |
A | HOH764 |
site_id | AC6 |
Number of Residues | 12 |
Details | binding site for residue PHE A 406 |
Chain | Residue |
A | MET149 |
A | GLN153 |
A | ALA156 |
A | GLY180 |
A | LEU181 |
A | SER182 |
A | PHE211 |
A | SER213 |
A | LYS216 |
A | HOH577 |
B | ASP8 |
B | ASP9 |
site_id | AC7 |
Number of Residues | 5 |
Details | binding site for residue MN B 401 |
Chain | Residue |
B | CYS63 |
B | HIS270 |
B | GLU304 |
B | ASP324 |
B | HOH519 |
site_id | AC8 |
Number of Residues | 4 |
Details | binding site for residue PEG B 402 |
Chain | Residue |
B | TRP106 |
B | LEU115 |
B | ASP116 |
B | GLY117 |
site_id | AC9 |
Number of Residues | 8 |
Details | binding site for residue PEG B 403 |
Chain | Residue |
A | SER208 |
A | HIS209 |
A | HOH536 |
A | HOH555 |
B | GLY105 |
B | PHE119 |
B | HOH526 |
B | HOH648 |
site_id | AD1 |
Number of Residues | 14 |
Details | binding site for residue PEP B 404 |
Chain | Residue |
B | ARG94 |
B | TYR96 |
B | LYS99 |
B | GLU145 |
B | LYS188 |
B | ARG236 |
B | HIS270 |
B | HOH519 |
B | HOH543 |
B | HOH589 |
B | HOH593 |
B | HOH596 |
B | HOH632 |
B | HOH638 |
site_id | AD2 |
Number of Residues | 3 |
Details | binding site for residue SO4 B 405 |
Chain | Residue |
B | ARG256 |
B | ALA257 |
B | GLY259 |
site_id | AD3 |
Number of Residues | 2 |
Details | binding site for residue SO4 B 406 |
Chain | Residue |
B | TYR26 |
B | HOH682 |
site_id | AD4 |
Number of Residues | 11 |
Details | binding site for residue PHE B 407 |
Chain | Residue |
A | ASP8 |
A | ASP9 |
B | MET149 |
B | GLN153 |
B | ALA156 |
B | GLY180 |
B | LEU181 |
B | SER182 |
B | SER213 |
B | HOH620 |
B | HOH732 |
site_id | AD5 |
Number of Residues | 5 |
Details | binding site for residue MN C 401 |
Chain | Residue |
C | CYS63 |
C | HIS270 |
C | GLU304 |
C | ASP324 |
C | HOH516 |
site_id | AD6 |
Number of Residues | 2 |
Details | binding site for residue PEG C 402 |
Chain | Residue |
C | TRP106 |
C | LEU115 |
site_id | AD7 |
Number of Residues | 14 |
Details | binding site for residue PEP C 403 |
Chain | Residue |
C | HOH566 |
C | HOH588 |
C | HOH607 |
C | HOH680 |
C | ARG94 |
C | TYR96 |
C | LYS99 |
C | GLU145 |
C | LYS188 |
C | ARG236 |
C | HIS270 |
C | HOH516 |
C | HOH550 |
C | HOH555 |
site_id | AD8 |
Number of Residues | 12 |
Details | binding site for residue PHE C 404 |
Chain | Residue |
C | MET149 |
C | GLN153 |
C | ALA156 |
C | GLY180 |
C | LEU181 |
C | SER182 |
C | PHE211 |
C | SER213 |
C | HOH562 |
C | HOH751 |
D | ASP8 |
D | ASP9 |
site_id | AD9 |
Number of Residues | 5 |
Details | binding site for residue MN D 401 |
Chain | Residue |
D | CYS63 |
D | HIS270 |
D | GLU304 |
D | ASP324 |
D | HOH506 |
site_id | AE1 |
Number of Residues | 3 |
Details | binding site for residue CL D 402 |
Chain | Residue |
C | HOH737 |
C | HOH826 |
D | LYS216 |
site_id | AE2 |
Number of Residues | 5 |
Details | binding site for residue CL D 403 |
Chain | Residue |
C | ARG167 |
C | HOH546 |
D | GLU170 |
D | GLN172 |
D | ARG175 |
site_id | AE3 |
Number of Residues | 13 |
Details | binding site for residue PEP D 404 |
Chain | Residue |
D | ARG94 |
D | TYR96 |
D | LYS99 |
D | GLU145 |
D | LYS188 |
D | ARG236 |
D | HIS270 |
D | HOH506 |
D | HOH507 |
D | HOH512 |
D | HOH587 |
D | HOH616 |
D | HOH625 |
site_id | AE4 |
Number of Residues | 2 |
Details | binding site for residue SO4 D 405 |
Chain | Residue |
D | TYR26 |
D | GLU27 |
site_id | AE5 |
Number of Residues | 12 |
Details | binding site for residue PHE D 406 |
Chain | Residue |
C | ASP8 |
C | ASP9 |
D | MET149 |
D | GLN153 |
D | ALA156 |
D | GLY180 |
D | LEU181 |
D | SER182 |
D | SER213 |
D | VAL223 |
D | HOH545 |
D | HOH652 |