5D05
Neisseria meningitidis 3 deoxy-D-arabino-heptulosonate 7-phosphate synthase Lys107Ala variant regulated
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003849 | molecular_function | 3-deoxy-7-phosphoheptulonate synthase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0008652 | biological_process | amino acid biosynthetic process |
| A | 0009058 | biological_process | biosynthetic process |
| A | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
| A | 0009423 | biological_process | chorismate biosynthetic process |
| A | 0016740 | molecular_function | transferase activity |
| A | 0042802 | molecular_function | identical protein binding |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0003849 | molecular_function | 3-deoxy-7-phosphoheptulonate synthase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0008652 | biological_process | amino acid biosynthetic process |
| B | 0009058 | biological_process | biosynthetic process |
| B | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
| B | 0009423 | biological_process | chorismate biosynthetic process |
| B | 0016740 | molecular_function | transferase activity |
| B | 0042802 | molecular_function | identical protein binding |
| B | 0046872 | molecular_function | metal ion binding |
| C | 0003849 | molecular_function | 3-deoxy-7-phosphoheptulonate synthase activity |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0008652 | biological_process | amino acid biosynthetic process |
| C | 0009058 | biological_process | biosynthetic process |
| C | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
| C | 0009423 | biological_process | chorismate biosynthetic process |
| C | 0016740 | molecular_function | transferase activity |
| C | 0042802 | molecular_function | identical protein binding |
| C | 0046872 | molecular_function | metal ion binding |
| D | 0003849 | molecular_function | 3-deoxy-7-phosphoheptulonate synthase activity |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0008652 | biological_process | amino acid biosynthetic process |
| D | 0009058 | biological_process | biosynthetic process |
| D | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
| D | 0009423 | biological_process | chorismate biosynthetic process |
| D | 0016740 | molecular_function | transferase activity |
| D | 0042802 | molecular_function | identical protein binding |
| D | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | binding site for residue MN A 401 |
| Chain | Residue |
| A | CYS63 |
| A | HIS270 |
| A | GLU304 |
| A | ASP324 |
| A | HOH521 |
| site_id | AC2 |
| Number of Residues | 1 |
| Details | binding site for residue CL A 402 |
| Chain | Residue |
| A | LYS216 |
| site_id | AC3 |
| Number of Residues | 11 |
| Details | binding site for residue PEP A 403 |
| Chain | Residue |
| A | ARG236 |
| A | HIS270 |
| A | HOH512 |
| A | HOH521 |
| A | HOH546 |
| A | HOH652 |
| A | HOH653 |
| A | HOH694 |
| A | ARG94 |
| A | GLU145 |
| A | LYS188 |
| site_id | AC4 |
| Number of Residues | 1 |
| Details | binding site for residue SO4 A 404 |
| Chain | Residue |
| A | TYR26 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | binding site for residue PGE A 405 |
| Chain | Residue |
| A | LEU115 |
| A | ASP116 |
| A | GLY117 |
| A | ASP313 |
| A | HOH764 |
| site_id | AC6 |
| Number of Residues | 12 |
| Details | binding site for residue PHE A 406 |
| Chain | Residue |
| A | MET149 |
| A | GLN153 |
| A | ALA156 |
| A | GLY180 |
| A | LEU181 |
| A | SER182 |
| A | PHE211 |
| A | SER213 |
| A | LYS216 |
| A | HOH577 |
| B | ASP8 |
| B | ASP9 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | binding site for residue MN B 401 |
| Chain | Residue |
| B | CYS63 |
| B | HIS270 |
| B | GLU304 |
| B | ASP324 |
| B | HOH519 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | binding site for residue PEG B 402 |
| Chain | Residue |
| B | TRP106 |
| B | LEU115 |
| B | ASP116 |
| B | GLY117 |
| site_id | AC9 |
| Number of Residues | 8 |
| Details | binding site for residue PEG B 403 |
| Chain | Residue |
| A | SER208 |
| A | HIS209 |
| A | HOH536 |
| A | HOH555 |
| B | GLY105 |
| B | PHE119 |
| B | HOH526 |
| B | HOH648 |
| site_id | AD1 |
| Number of Residues | 14 |
| Details | binding site for residue PEP B 404 |
| Chain | Residue |
| B | ARG94 |
| B | TYR96 |
| B | LYS99 |
| B | GLU145 |
| B | LYS188 |
| B | ARG236 |
| B | HIS270 |
| B | HOH519 |
| B | HOH543 |
| B | HOH589 |
| B | HOH593 |
| B | HOH596 |
| B | HOH632 |
| B | HOH638 |
| site_id | AD2 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 B 405 |
| Chain | Residue |
| B | ARG256 |
| B | ALA257 |
| B | GLY259 |
| site_id | AD3 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 B 406 |
| Chain | Residue |
| B | TYR26 |
| B | HOH682 |
| site_id | AD4 |
| Number of Residues | 11 |
| Details | binding site for residue PHE B 407 |
| Chain | Residue |
| A | ASP8 |
| A | ASP9 |
| B | MET149 |
| B | GLN153 |
| B | ALA156 |
| B | GLY180 |
| B | LEU181 |
| B | SER182 |
| B | SER213 |
| B | HOH620 |
| B | HOH732 |
| site_id | AD5 |
| Number of Residues | 5 |
| Details | binding site for residue MN C 401 |
| Chain | Residue |
| C | CYS63 |
| C | HIS270 |
| C | GLU304 |
| C | ASP324 |
| C | HOH516 |
| site_id | AD6 |
| Number of Residues | 2 |
| Details | binding site for residue PEG C 402 |
| Chain | Residue |
| C | TRP106 |
| C | LEU115 |
| site_id | AD7 |
| Number of Residues | 14 |
| Details | binding site for residue PEP C 403 |
| Chain | Residue |
| C | HOH566 |
| C | HOH588 |
| C | HOH607 |
| C | HOH680 |
| C | ARG94 |
| C | TYR96 |
| C | LYS99 |
| C | GLU145 |
| C | LYS188 |
| C | ARG236 |
| C | HIS270 |
| C | HOH516 |
| C | HOH550 |
| C | HOH555 |
| site_id | AD8 |
| Number of Residues | 12 |
| Details | binding site for residue PHE C 404 |
| Chain | Residue |
| C | MET149 |
| C | GLN153 |
| C | ALA156 |
| C | GLY180 |
| C | LEU181 |
| C | SER182 |
| C | PHE211 |
| C | SER213 |
| C | HOH562 |
| C | HOH751 |
| D | ASP8 |
| D | ASP9 |
| site_id | AD9 |
| Number of Residues | 5 |
| Details | binding site for residue MN D 401 |
| Chain | Residue |
| D | CYS63 |
| D | HIS270 |
| D | GLU304 |
| D | ASP324 |
| D | HOH506 |
| site_id | AE1 |
| Number of Residues | 3 |
| Details | binding site for residue CL D 402 |
| Chain | Residue |
| C | HOH737 |
| C | HOH826 |
| D | LYS216 |
| site_id | AE2 |
| Number of Residues | 5 |
| Details | binding site for residue CL D 403 |
| Chain | Residue |
| C | ARG167 |
| C | HOH546 |
| D | GLU170 |
| D | GLN172 |
| D | ARG175 |
| site_id | AE3 |
| Number of Residues | 13 |
| Details | binding site for residue PEP D 404 |
| Chain | Residue |
| D | ARG94 |
| D | TYR96 |
| D | LYS99 |
| D | GLU145 |
| D | LYS188 |
| D | ARG236 |
| D | HIS270 |
| D | HOH506 |
| D | HOH507 |
| D | HOH512 |
| D | HOH587 |
| D | HOH616 |
| D | HOH625 |
| site_id | AE4 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 D 405 |
| Chain | Residue |
| D | TYR26 |
| D | GLU27 |
| site_id | AE5 |
| Number of Residues | 12 |
| Details | binding site for residue PHE D 406 |
| Chain | Residue |
| C | ASP8 |
| C | ASP9 |
| D | MET149 |
| D | GLN153 |
| D | ALA156 |
| D | GLY180 |
| D | LEU181 |
| D | SER182 |
| D | SER213 |
| D | VAL223 |
| D | HOH545 |
| D | HOH652 |
