5D04
Neisseria meningitidis 3 deoxy-D-arabino-heptulosonate 7-phosphate synthase Val223Ala variant regulated
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| C | 0003849 | molecular_function | 3-deoxy-7-phosphoheptulonate synthase activity |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0008652 | biological_process | amino acid biosynthetic process |
| C | 0009058 | biological_process | biosynthetic process |
| C | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
| C | 0009423 | biological_process | chorismate biosynthetic process |
| C | 0016740 | molecular_function | transferase activity |
| C | 0046872 | molecular_function | metal ion binding |
| D | 0003849 | molecular_function | 3-deoxy-7-phosphoheptulonate synthase activity |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0008652 | biological_process | amino acid biosynthetic process |
| D | 0009058 | biological_process | biosynthetic process |
| D | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
| D | 0009423 | biological_process | chorismate biosynthetic process |
| D | 0016740 | molecular_function | transferase activity |
| D | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | binding site for residue MN C 401 |
| Chain | Residue |
| C | CYS63 |
| C | HIS270 |
| C | GLU304 |
| C | ASP324 |
| C | HOH732 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue CL C 402 |
| Chain | Residue |
| C | ARG175 |
| C | ASP200 |
| C | HOH508 |
| D | THR102 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue CL C 403 |
| Chain | Residue |
| C | LYS188 |
| C | ARG236 |
| C | HIS270 |
| C | HOH704 |
| C | HOH725 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | binding site for residue CL C 404 |
| Chain | Residue |
| C | TYR96 |
| C | ALA163 |
| C | LYS188 |
| C | HOH574 |
| C | HOH733 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | binding site for residue CL C 405 |
| Chain | Residue |
| C | LYS216 |
| D | HOH573 |
| D | HOH580 |
| D | HOH836 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | binding site for residue PEG C 406 |
| Chain | Residue |
| C | TYR26 |
| C | GLU27 |
| C | PHE123 |
| C | ARG126 |
| site_id | AC7 |
| Number of Residues | 12 |
| Details | binding site for residue PHE C 407 |
| Chain | Residue |
| C | MET149 |
| C | GLN153 |
| C | ALA156 |
| C | GLY180 |
| C | LEU181 |
| C | SER182 |
| C | PHE211 |
| C | SER213 |
| C | LYS216 |
| C | HOH631 |
| D | ASP8 |
| D | ASP9 |
| site_id | AC8 |
| Number of Residues | 1 |
| Details | binding site for residue EDO C 408 |
| Chain | Residue |
| C | ARG55 |
| site_id | AC9 |
| Number of Residues | 2 |
| Details | binding site for residue EDO C 409 |
| Chain | Residue |
| C | TRP106 |
| C | GLY117 |
| site_id | AD1 |
| Number of Residues | 5 |
| Details | binding site for residue MN D 401 |
| Chain | Residue |
| D | CYS63 |
| D | HIS270 |
| D | GLU304 |
| D | ASP324 |
| D | HOH768 |
| site_id | AD2 |
| Number of Residues | 5 |
| Details | binding site for residue CL D 402 |
| Chain | Residue |
| D | LYS188 |
| D | ARG236 |
| D | HIS270 |
| D | HOH727 |
| D | HOH749 |
| site_id | AD3 |
| Number of Residues | 5 |
| Details | binding site for residue CL D 403 |
| Chain | Residue |
| D | TYR96 |
| D | ALA163 |
| D | LYS188 |
| D | HOH603 |
| D | HOH763 |
| site_id | AD4 |
| Number of Residues | 3 |
| Details | binding site for residue PEG D 404 |
| Chain | Residue |
| D | TRP106 |
| D | LEU115 |
| D | ASP313 |
| site_id | AD5 |
| Number of Residues | 2 |
| Details | binding site for residue PEG D 405 |
| Chain | Residue |
| D | PHE123 |
| D | PEG406 |
| site_id | AD6 |
| Number of Residues | 5 |
| Details | binding site for residue PEG D 406 |
| Chain | Residue |
| D | TYR26 |
| D | GLU27 |
| D | PHE123 |
| D | ARG126 |
| D | PEG405 |
| site_id | AD7 |
| Number of Residues | 13 |
| Details | binding site for residue PHE D 407 |
| Chain | Residue |
| C | ASP8 |
| C | ASP9 |
| D | MET149 |
| D | GLN153 |
| D | ALA156 |
| D | GLY180 |
| D | LEU181 |
| D | SER182 |
| D | PHE211 |
| D | SER213 |
| D | LYS216 |
| D | HOH565 |
| D | HOH732 |
| site_id | AD8 |
| Number of Residues | 4 |
| Details | binding site for residue EDO D 408 |
| Chain | Residue |
| D | ARG101 |
| D | THR102 |
| D | THR103 |
| D | ARG167 |
| site_id | AD9 |
| Number of Residues | 8 |
| Details | binding site for residue EDO D 409 |
| Chain | Residue |
| C | GLY330 |
| C | GLU333 |
| D | LEU307 |
| D | GLY328 |
| D | TRP329 |
| D | GLY330 |
| D | HOH626 |
| D | HOH672 |
