5D03
Neisseria meningitidis 3 deoxy-D-arabino-heptulosonate 7-phosphate synthase Val223Ala variant
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003849 | molecular_function | 3-deoxy-7-phosphoheptulonate synthase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0008652 | biological_process | amino acid biosynthetic process |
| A | 0009058 | biological_process | biosynthetic process |
| A | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
| A | 0009423 | biological_process | chorismate biosynthetic process |
| A | 0016740 | molecular_function | transferase activity |
| A | 0042802 | molecular_function | identical protein binding |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0003849 | molecular_function | 3-deoxy-7-phosphoheptulonate synthase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0008652 | biological_process | amino acid biosynthetic process |
| B | 0009058 | biological_process | biosynthetic process |
| B | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
| B | 0009423 | biological_process | chorismate biosynthetic process |
| B | 0016740 | molecular_function | transferase activity |
| B | 0042802 | molecular_function | identical protein binding |
| B | 0046872 | molecular_function | metal ion binding |
| C | 0003849 | molecular_function | 3-deoxy-7-phosphoheptulonate synthase activity |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0008652 | biological_process | amino acid biosynthetic process |
| C | 0009058 | biological_process | biosynthetic process |
| C | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
| C | 0009423 | biological_process | chorismate biosynthetic process |
| C | 0016740 | molecular_function | transferase activity |
| C | 0042802 | molecular_function | identical protein binding |
| C | 0046872 | molecular_function | metal ion binding |
| D | 0003849 | molecular_function | 3-deoxy-7-phosphoheptulonate synthase activity |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0008652 | biological_process | amino acid biosynthetic process |
| D | 0009058 | biological_process | biosynthetic process |
| D | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
| D | 0009423 | biological_process | chorismate biosynthetic process |
| D | 0016740 | molecular_function | transferase activity |
| D | 0042802 | molecular_function | identical protein binding |
| D | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue MN A 401 |
| Chain | Residue |
| A | CYS63 |
| A | HIS270 |
| A | GLU304 |
| A | ASP324 |
| A | PEP402 |
| A | HOH549 |
| site_id | AC2 |
| Number of Residues | 15 |
| Details | binding site for residue PEP A 402 |
| Chain | Residue |
| A | GLY165 |
| A | ALA166 |
| A | ARG167 |
| A | LYS188 |
| A | ARG236 |
| A | HIS270 |
| A | MN401 |
| A | HOH519 |
| A | HOH523 |
| A | HOH541 |
| A | HOH549 |
| A | HOH630 |
| A | ARG94 |
| A | LYS99 |
| A | GLU145 |
| site_id | AC3 |
| Number of Residues | 2 |
| Details | binding site for residue CL A 403 |
| Chain | Residue |
| A | ARG101 |
| A | THR102 |
| site_id | AC4 |
| Number of Residues | 2 |
| Details | binding site for residue EDO A 404 |
| Chain | Residue |
| A | LEU115 |
| A | GLY117 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | binding site for residue MN B 401 |
| Chain | Residue |
| B | CYS63 |
| B | HIS270 |
| B | GLU304 |
| B | ASP324 |
| B | PEP402 |
| B | HOH639 |
| site_id | AC6 |
| Number of Residues | 17 |
| Details | binding site for residue PEP B 402 |
| Chain | Residue |
| B | ARG94 |
| B | TYR96 |
| B | LYS99 |
| B | GLU145 |
| B | GLY165 |
| B | ALA166 |
| B | ARG167 |
| B | LYS188 |
| B | ARG236 |
| B | HIS270 |
| B | GLU304 |
| B | MN401 |
| B | HOH512 |
| B | HOH517 |
| B | HOH535 |
| B | HOH599 |
| B | HOH639 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | binding site for residue MN C 401 |
| Chain | Residue |
| C | CYS63 |
| C | HIS270 |
| C | GLU304 |
| C | ASP324 |
| C | PEP402 |
| C | HOH510 |
| site_id | AC8 |
| Number of Residues | 14 |
| Details | binding site for residue PEP C 402 |
| Chain | Residue |
| C | ARG94 |
| C | LYS99 |
| C | GLU145 |
| C | GLY165 |
| C | ALA166 |
| C | ARG167 |
| C | LYS188 |
| C | ARG236 |
| C | HIS270 |
| C | MN401 |
| C | HOH502 |
| C | HOH510 |
| C | HOH529 |
| C | HOH580 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | binding site for residue CL C 403 |
| Chain | Residue |
| C | ILE65 |
| C | TYR96 |
| C | PHE97 |
| C | GLY108 |
| C | LEU109 |
| site_id | AD1 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 C 404 |
| Chain | Residue |
| C | ARG101 |
| C | THR102 |
| site_id | AD2 |
| Number of Residues | 6 |
| Details | binding site for residue MN D 401 |
| Chain | Residue |
| D | CYS63 |
| D | HIS270 |
| D | GLU304 |
| D | ASP324 |
| D | PEP402 |
| D | HOH520 |
| site_id | AD3 |
| Number of Residues | 17 |
| Details | binding site for residue PEP D 402 |
| Chain | Residue |
| D | ARG94 |
| D | TYR96 |
| D | LYS99 |
| D | GLU145 |
| D | GLY165 |
| D | ALA166 |
| D | ARG167 |
| D | LYS188 |
| D | ARG236 |
| D | HIS270 |
| D | GLU304 |
| D | MN401 |
| D | HOH502 |
| D | HOH520 |
| D | HOH543 |
| D | HOH548 |
| D | HOH549 |
| site_id | AD4 |
| Number of Residues | 6 |
| Details | binding site for residue CL D 403 |
| Chain | Residue |
| D | TYR96 |
| D | PHE97 |
| D | TRP106 |
| D | GLY108 |
| D | LEU109 |
| D | ILE65 |
| site_id | AD5 |
| Number of Residues | 2 |
| Details | binding site for residue CL D 404 |
| Chain | Residue |
| D | ARG101 |
| D | THR102 |
| site_id | AD6 |
| Number of Residues | 3 |
| Details | binding site for residue PEG D 405 |
| Chain | Residue |
| D | ARG279 |
| D | GLU282 |
| D | HOH529 |
| site_id | AD7 |
| Number of Residues | 1 |
| Details | binding site for residue EDO D 406 |
| Chain | Residue |
| D | LEU115 |
