5CZS
Neisseria meningitidis 3 dexy-D-arabino-heptulosonate 7-phosphate synthase Glu98Ala variant regulated
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003849 | molecular_function | 3-deoxy-7-phosphoheptulonate synthase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0009058 | biological_process | biosynthetic process |
| A | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
| A | 0009423 | biological_process | chorismate biosynthetic process |
| A | 0042802 | molecular_function | identical protein binding |
| B | 0003849 | molecular_function | 3-deoxy-7-phosphoheptulonate synthase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0009058 | biological_process | biosynthetic process |
| B | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
| B | 0009423 | biological_process | chorismate biosynthetic process |
| B | 0042802 | molecular_function | identical protein binding |
| C | 0003849 | molecular_function | 3-deoxy-7-phosphoheptulonate synthase activity |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0009058 | biological_process | biosynthetic process |
| C | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
| C | 0009423 | biological_process | chorismate biosynthetic process |
| C | 0042802 | molecular_function | identical protein binding |
| D | 0003849 | molecular_function | 3-deoxy-7-phosphoheptulonate synthase activity |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0009058 | biological_process | biosynthetic process |
| D | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
| D | 0009423 | biological_process | chorismate biosynthetic process |
| D | 0042802 | molecular_function | identical protein binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue MN A 401 |
| Chain | Residue |
| A | CYS63 |
| A | HIS270 |
| A | GLU304 |
| A | ASP324 |
| A | PEP402 |
| A | HOH549 |
| site_id | AC2 |
| Number of Residues | 13 |
| Details | binding site for residue PEP A 402 |
| Chain | Residue |
| A | ALA166 |
| A | ARG167 |
| A | LYS188 |
| A | ARG236 |
| A | HIS270 |
| A | MN401 |
| A | HOH509 |
| A | HOH528 |
| A | HOH549 |
| A | HOH575 |
| A | ARG94 |
| A | TYR96 |
| A | PRO100 |
| site_id | AC3 |
| Number of Residues | 12 |
| Details | binding site for residue PHE A 403 |
| Chain | Residue |
| A | MET149 |
| A | GLN153 |
| A | ALA156 |
| A | GLY180 |
| A | LEU181 |
| A | SER182 |
| A | PHE211 |
| A | SER213 |
| A | LYS216 |
| A | HOH515 |
| B | ASP8 |
| B | ASP9 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 404 |
| Chain | Residue |
| A | SER269 |
| A | HIS270 |
| A | LYS275 |
| A | GLU304 |
| A | ASP324 |
| site_id | AC5 |
| Number of Residues | 1 |
| Details | binding site for residue EDO A 405 |
| Chain | Residue |
| A | ASN137 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | binding site for residue MN B 401 |
| Chain | Residue |
| B | CYS63 |
| B | HIS270 |
| B | GLU304 |
| B | ASP324 |
| site_id | AC7 |
| Number of Residues | 11 |
| Details | binding site for residue PEP B 402 |
| Chain | Residue |
| B | ARG94 |
| B | TYR96 |
| B | PRO100 |
| B | GLU145 |
| B | ALA166 |
| B | ARG167 |
| B | LYS188 |
| B | ARG236 |
| B | HIS270 |
| B | HOH533 |
| B | HOH542 |
| site_id | AC8 |
| Number of Residues | 10 |
| Details | binding site for residue PHE B 403 |
| Chain | Residue |
| A | ASP8 |
| A | ASP9 |
| B | MET149 |
| B | GLN153 |
| B | GLY180 |
| B | LEU181 |
| B | SER182 |
| B | SER213 |
| B | LYS216 |
| B | HOH504 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | binding site for residue MN C 401 |
| Chain | Residue |
| C | CYS63 |
| C | HIS270 |
| C | GLU304 |
| C | ASP324 |
| C | HOH520 |
| site_id | AD1 |
| Number of Residues | 8 |
| Details | binding site for residue PEP C 402 |
| Chain | Residue |
| C | TYR96 |
| C | ALA166 |
| C | ARG167 |
| C | LYS188 |
| C | ARG236 |
| C | HIS270 |
| C | HOH503 |
| C | HOH520 |
| site_id | AD2 |
| Number of Residues | 11 |
| Details | binding site for residue PHE C 403 |
| Chain | Residue |
| C | MET149 |
| C | GLN153 |
| C | GLY180 |
| C | LEU181 |
| C | SER182 |
| C | SER213 |
| C | LYS216 |
| C | VAL223 |
| C | HOH532 |
| D | ASP8 |
| D | ASP9 |
| site_id | AD3 |
| Number of Residues | 3 |
| Details | binding site for residue EDO C 404 |
| Chain | Residue |
| C | SER134 |
| C | ASN137 |
| C | MET138 |
| site_id | AD4 |
| Number of Residues | 6 |
| Details | binding site for residue PEG C 405 |
| Chain | Residue |
| C | ARG40 |
| C | ARG82 |
| C | GLU86 |
| C | LEU89 |
| C | ILE91 |
| C | HOH511 |
| site_id | AD5 |
| Number of Residues | 5 |
| Details | binding site for residue MN D 401 |
| Chain | Residue |
| D | HOH567 |
| D | CYS63 |
| D | HIS270 |
| D | GLU304 |
| D | ASP324 |
| site_id | AD6 |
| Number of Residues | 13 |
| Details | binding site for residue PEP D 402 |
| Chain | Residue |
| D | ARG94 |
| D | TYR96 |
| D | PRO100 |
| D | ALA166 |
| D | ARG167 |
| D | LYS188 |
| D | ARG236 |
| D | HIS270 |
| D | MET302 |
| D | HOH535 |
| D | HOH536 |
| D | HOH567 |
| D | HOH572 |
| site_id | AD7 |
| Number of Residues | 9 |
| Details | binding site for residue PHE D 403 |
| Chain | Residue |
| C | ASP9 |
| D | MET149 |
| D | GLN153 |
| D | GLY180 |
| D | LEU181 |
| D | SER182 |
| D | SER213 |
| D | VAL223 |
| D | HOH571 |
