5CZR

Crystal Structure of Human Protocadherin-24 EC1-2

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005509	molecular_function	calcium ion binding
A	0005886	cellular_component	plasma membrane
A	0007155	biological_process	cell adhesion
A	0007156	biological_process	homophilic cell-cell adhesion
A	0016020	cellular_component	membrane
B	0005509	molecular_function	calcium ion binding
B	0005886	cellular_component	plasma membrane
B	0007155	biological_process	cell adhesion
B	0007156	biological_process	homophilic cell-cell adhesion
B	0016020	cellular_component	membrane
C	0005509	molecular_function	calcium ion binding
C	0005886	cellular_component	plasma membrane
C	0007155	biological_process	cell adhesion
C	0007156	biological_process	homophilic cell-cell adhesion
C	0016020	cellular_component	membrane
D	0005509	molecular_function	calcium ion binding
D	0005886	cellular_component	plasma membrane
D	0007155	biological_process	cell adhesion
D	0007156	biological_process	homophilic cell-cell adhesion
D	0016020	cellular_component	membrane

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	binding site for residue CA A 1001

Chain	Residue
A	ASN1
A	VAL2
A	ASP32
A	ASP34
A	ASP36
A	ASP81

---

site_id	AC2
Number of Residues	6
Details	binding site for residue CA A 1002

Chain	Residue
A	ASP99
A	HOH1138
A	HOH1154
A	GLU17
A	ASP66
A	GLU68

---

site_id	AC3
Number of Residues	6
Details	binding site for residue CA A 1003

Chain	Residue
A	GLU17
A	GLU68
A	ASP96
A	ARG97
A	ASP99
A	ASP132

---

site_id	AC4
Number of Residues	6
Details	binding site for residue CA A 1004

Chain	Residue
A	ASN98
A	ASN100
A	ASP130
A	ASP132
A	ALA136
A	ASP188

---

site_id	AC5
Number of Residues	6
Details	binding site for residue CA B 301

Chain	Residue
B	ASN1
B	VAL2
B	ASP32
B	ASP34
B	ASP36
B	ASP81

---

site_id	AC6
Number of Residues	6
Details	binding site for residue CA B 302

Chain	Residue
B	GLU17
B	ASP66
B	GLU68
B	ASP99
B	HOH441
B	HOH447

---

site_id	AC7
Number of Residues	6
Details	binding site for residue CA B 303

Chain	Residue
B	GLU17
B	GLU68
B	ASP96
B	ARG97
B	ASP99
B	ASP132

---

site_id	AC8
Number of Residues	6
Details	binding site for residue CA B 304

Chain	Residue
B	ASN98
B	ASN100
B	ASP130
B	ASP132
B	ALA136
B	ASP188

---

site_id	AC9
Number of Residues	6
Details	binding site for residue CA C 301

Chain	Residue
C	ASN1
C	VAL2
C	ASP32
C	ASP34
C	ASP36
C	ASP81

---

site_id	AD1
Number of Residues	6
Details	binding site for residue CA C 302

Chain	Residue
C	GLU17
C	ASP66
C	GLU68
C	ASP99
C	HOH434
C	HOH454

---

site_id	AD2
Number of Residues	6
Details	binding site for residue CA C 303

Chain	Residue
C	GLU17
C	GLU68
C	ASP96
C	ARG97
C	ASP99
C	ASP132

---

site_id	AD3
Number of Residues	6
Details	binding site for residue CA C 304

Chain	Residue
C	ASN98
C	ASN100
C	ASP130
C	ASP132
C	ALA136
C	ASP188

---

site_id	AD4
Number of Residues	6
Details	binding site for residue CA D 301

Chain	Residue
D	ASN1
D	VAL2
D	ASP32
D	ASP34
D	ASP36
D	ASP81

---

site_id	AD5
Number of Residues	6
Details	binding site for residue CA D 302

Chain	Residue
D	GLU17
D	ASP66
D	GLU68
D	ASP99
D	HOH427
D	HOH432

---

site_id	AD6
Number of Residues	6
Details	binding site for residue CA D 303

Chain	Residue
D	GLU17
D	GLU68
D	ASP96
D	ARG97
D	ASP99
D	ASP132

---

site_id	AD7
Number of Residues	6
Details	binding site for residue CA D 304

Chain	Residue
D	ASN98
D	ASN100
D	ASP130
D	ASP132
D	ALA136
D	ASP188

---

Functional Information from PROSITE/UniProt

site_id	PS00232
Number of Residues	11
Details	CADHERIN_1 Cadherin domain signature. ViVeDrNDNaP

Chain	Residue	Details
A	VAL92-PRO102

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	388
Details	Domain: {"description":"Cadherin 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00043","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	20
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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