Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003723 | molecular_function | RNA binding |
| A | 0003968 | molecular_function | RNA-directed RNA polymerase activity |
| A | 0039694 | biological_process | viral RNA genome replication |
| B | 0003723 | molecular_function | RNA binding |
| B | 0003968 | molecular_function | RNA-directed RNA polymerase activity |
| B | 0039694 | biological_process | viral RNA genome replication |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 17 |
| Details | binding site for residue 55W A 601 |
| Chain | Residue |
| A | ARG422 |
| A | VAL494 |
| A | PRO495 |
| A | PRO496 |
| A | LEU497 |
| A | ARG501 |
| A | TRP528 |
| A | HOH739 |
| A | HOH760 |
| A | MET423 |
| A | LEU474 |
| A | HIS475 |
| A | SER476 |
| A | TYR477 |
| A | ILE482 |
| A | LEU489 |
| A | ARG490 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | binding site for residue GOL A 602 |
| Chain | Residue |
| A | ALA97 |
| A | LYS98 |
| A | HOH822 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | binding site for residue GOL A 603 |
| Chain | Residue |
| A | THR499 |
| A | ARG503 |
| A | HOH812 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | binding site for residue MES A 604 |
| Chain | Residue |
| A | LEU497 |
| A | ARG498 |
| A | ARG501 |
| B | GLU202 |
| B | VAL205 |
| B | ASN206 |
| B | TYR382 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | binding site for residue PEG A 605 |
| Chain | Residue |
| A | LEU83 |
| A | ARG120 |
| A | HOH708 |
| site_id | AC6 |
| Number of Residues | 7 |
| Details | binding site for residue PEG A 606 |
| Chain | Residue |
| A | GLU248 |
| A | GLN251 |
| A | HOH862 |
| B | THR130 |
| B | GLU131 |
| B | ARG254 |
| B | GLU258 |
| site_id | AC7 |
| Number of Residues | 2 |
| Details | binding site for residue PEG A 607 |
| Chain | Residue |
| A | LEU469 |
| A | SER470 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | binding site for residue PEG A 608 |
| Chain | Residue |
| A | SER96 |
| A | ALA97 |
| A | GLY283 |
| A | GLY557 |
| A | HOH724 |
| site_id | AC9 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 A 609 |
| Chain | Residue |
| A | GLU440 |
| A | GLY516 |
| A | ARG517 |
| site_id | AD1 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 A 610 |
| Chain | Residue |
| A | ARG498 |
| A | ARG505 |
| A | HOH953 |
| site_id | AD2 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 A 611 |
| Chain | Residue |
| A | SER112 |
| A | SER113 |
| A | HOH911 |
| site_id | AD3 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 A 612 |
| Chain | Residue |
| A | ARG48 |
| A | LYS51 |
| A | THR221 |
| A | CYS223 |
| A | HOH832 |
| A | HOH933 |
| site_id | AD4 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 A 613 |
| Chain | Residue |
| A | ARG114 |
| A | HOH749 |
| B | PRO22 |
| B | ILE23 |
| B | ASN24 |
| B | ARG401 |
| site_id | AD5 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 A 614 |
| Chain | Residue |
| A | HIS502 |
| A | ARG505 |
| A | HOH854 |
| site_id | AD6 |
| Number of Residues | 7 |
| Details | binding site for residue SO4 A 615 |
| Chain | Residue |
| A | ARG498 |
| A | HOH705 |
| A | HOH713 |
| A | HOH740 |
| A | HOH937 |
| A | HOH988 |
| B | GLN199 |
| site_id | AD7 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 A 616 |
| Chain | Residue |
| A | THR287 |
| A | ASN291 |
| A | GLY317 |
| A | ASP318 |
| A | HOH774 |
| site_id | AD8 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 A 617 |
| Chain | Residue |
| A | ARG32 |
| A | HIS33 |
| A | HIS34 |
| A | ASN35 |
| site_id | AD9 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 A 618 |
| Chain | Residue |
| A | LYS79 |
| A | ASP244 |
| A | HOH1003 |
| B | LEU60 |
| B | LEU68 |
| B | HOH764 |
| site_id | AE1 |
| Number of Residues | 18 |
| Details | binding site for residue 55W B 601 |
| Chain | Residue |
| B | TYR477 |
| B | ILE482 |
| B | LEU489 |
| B | ARG490 |
| B | VAL494 |
| B | PRO495 |
| B | PRO496 |
| B | LEU497 |
| B | TRP528 |
| B | SO4611 |
| B | HOH816 |
| B | HOH1003 |
| B | LEU419 |
| B | ARG422 |
| B | MET423 |
| B | LEU474 |
| B | HIS475 |
| B | SER476 |
| site_id | AE2 |
| Number of Residues | 3 |
| Details | binding site for residue GOL B 602 |
| Chain | Residue |
| B | ARG380 |
| B | TYR382 |
| B | HOH970 |
| site_id | AE3 |
| Number of Residues | 4 |
| Details | binding site for residue GOL B 603 |
| Chain | Residue |
| B | SER96 |
| B | ALA97 |
| B | PHE162 |
| B | ARG168 |
| site_id | AE4 |
| Number of Residues | 2 |
| Details | binding site for residue GOL B 604 |
| Chain | Residue |
| B | ARG43 |
| B | HOH940 |
| site_id | AE5 |
| Number of Residues | 4 |
| Details | binding site for residue GOL B 605 |
| Chain | Residue |
| B | GLU143 |
| B | GLN446 |
| B | SER556 |
| B | HOH864 |
| site_id | AE6 |
| Number of Residues | 2 |
| Details | binding site for residue GOL B 606 |
| Chain | Residue |
| B | HIS502 |
| B | ARG505 |
| site_id | AE7 |
| Number of Residues | 8 |
| Details | binding site for residue PEG B 607 |
| Chain | Residue |
| A | GLU124 |
| A | ASP125 |
| A | GLU128 |
| A | HOH827 |
| B | ARG32 |
| B | PRO496 |
| B | THR499 |
| B | HOH969 |
| site_id | AE8 |
| Number of Residues | 4 |
| Details | binding site for residue PEG B 608 |
| Chain | Residue |
| B | GLU464 |
| B | LEU469 |
| B | SER470 |
| B | HOH730 |
| site_id | AE9 |
| Number of Residues | 7 |
| Details | binding site for residue SO4 B 609 |
| Chain | Residue |
| B | THR287 |
| B | SER288 |
| B | ASN291 |
| B | GLY317 |
| B | ASP318 |
| B | SER556 |
| B | HOH955 |
| site_id | AF1 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 B 610 |
| Chain | Residue |
| B | GLY516 |
| B | ARG517 |
| site_id | AF2 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 B 611 |
| Chain | Residue |
| B | PRO496 |
| B | LEU497 |
| B | ARG498 |
| B | 55W601 |
| B | HOH1011 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 236 |
| Details | Domain: {"description":"RdRp catalytic","evidences":[{"source":"PROSITE-ProRule","id":"PRU00539","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 6 |
| Details | Binding site: {"evidences":[{"source":"UniProtKB","id":"P26663","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | Modified residue: {"description":"Phosphoserine; by host","evidences":[{"source":"UniProtKB","id":"P26662","evidenceCode":"ECO:0000250"}]} |
