5CZ0
Neisseria meningitidis 3 dexy-D-arabino-heptulosonate 7-phosphate synthase Glu98Ala variant
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003849 | molecular_function | 3-deoxy-7-phosphoheptulonate synthase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0008652 | biological_process | amino acid biosynthetic process |
| A | 0009058 | biological_process | biosynthetic process |
| A | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
| A | 0009423 | biological_process | chorismate biosynthetic process |
| A | 0016740 | molecular_function | transferase activity |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0003849 | molecular_function | 3-deoxy-7-phosphoheptulonate synthase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0008652 | biological_process | amino acid biosynthetic process |
| B | 0009058 | biological_process | biosynthetic process |
| B | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
| B | 0009423 | biological_process | chorismate biosynthetic process |
| B | 0016740 | molecular_function | transferase activity |
| B | 0046872 | molecular_function | metal ion binding |
| C | 0003849 | molecular_function | 3-deoxy-7-phosphoheptulonate synthase activity |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0008652 | biological_process | amino acid biosynthetic process |
| C | 0009058 | biological_process | biosynthetic process |
| C | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
| C | 0009423 | biological_process | chorismate biosynthetic process |
| C | 0016740 | molecular_function | transferase activity |
| C | 0046872 | molecular_function | metal ion binding |
| D | 0003849 | molecular_function | 3-deoxy-7-phosphoheptulonate synthase activity |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0008652 | biological_process | amino acid biosynthetic process |
| D | 0009058 | biological_process | biosynthetic process |
| D | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
| D | 0009423 | biological_process | chorismate biosynthetic process |
| D | 0016740 | molecular_function | transferase activity |
| D | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue MN A 401 |
| Chain | Residue |
| A | CYS63 |
| A | HIS270 |
| A | GLU304 |
| A | ASP324 |
| A | PEP403 |
| A | HOH524 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 A 402 |
| Chain | Residue |
| A | EDO405 |
| A | PRO100 |
| A | ARG101 |
| A | THR102 |
| site_id | AC3 |
| Number of Residues | 14 |
| Details | binding site for residue PEP A 403 |
| Chain | Residue |
| A | ARG94 |
| A | TYR96 |
| A | LYS99 |
| A | GLU145 |
| A | GLY165 |
| A | ALA166 |
| A | ARG167 |
| A | LYS188 |
| A | ARG236 |
| A | HIS270 |
| A | MN401 |
| A | EDO405 |
| A | HOH502 |
| A | HOH524 |
| site_id | AC4 |
| Number of Residues | 1 |
| Details | binding site for residue EDO A 404 |
| Chain | Residue |
| A | PRO315 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 405 |
| Chain | Residue |
| A | LYS99 |
| A | PRO100 |
| A | ASP324 |
| A | SO4402 |
| A | PEP403 |
| A | HOH524 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | binding site for residue MN B 401 |
| Chain | Residue |
| B | CYS63 |
| B | HIS270 |
| B | GLU304 |
| B | ASP324 |
| site_id | AC7 |
| Number of Residues | 11 |
| Details | binding site for residue PEP B 402 |
| Chain | Residue |
| B | ARG94 |
| B | TYR96 |
| B | LYS99 |
| B | GLU145 |
| B | GLY165 |
| B | ALA166 |
| B | ARG167 |
| B | LYS188 |
| B | ARG236 |
| B | HIS270 |
| B | HOH507 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | binding site for residue MN C 401 |
| Chain | Residue |
| C | CYS63 |
| C | HIS270 |
| C | GLU304 |
| C | ASP324 |
| C | HOH504 |
| site_id | AC9 |
| Number of Residues | 10 |
| Details | binding site for residue PEP C 402 |
| Chain | Residue |
| C | ARG94 |
| C | TYR96 |
| C | GLU145 |
| C | ALA166 |
| C | ARG167 |
| C | LYS188 |
| C | ARG236 |
| C | HIS270 |
| C | HOH501 |
| C | HOH504 |
| site_id | AD1 |
| Number of Residues | 5 |
| Details | binding site for residue MN D 401 |
| Chain | Residue |
| D | CYS63 |
| D | HIS270 |
| D | GLU304 |
| D | ASP324 |
| D | PEP403 |
| site_id | AD2 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 D 402 |
| Chain | Residue |
| D | ARG101 |
| D | THR102 |
| site_id | AD3 |
| Number of Residues | 11 |
| Details | binding site for residue PEP D 403 |
| Chain | Residue |
| D | ARG94 |
| D | TYR96 |
| D | LYS99 |
| D | GLU145 |
| D | ALA166 |
| D | ARG167 |
| D | LYS188 |
| D | ARG236 |
| D | HIS270 |
| D | GLU304 |
| D | MN401 |
