Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

5CXK

Crystal structure of beta carbonic anhydrase from Vibrio cholerae

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004089	molecular_function	carbonate dehydratase activity
A	0005737	cellular_component	cytoplasm
A	0008270	molecular_function	zinc ion binding
A	0015976	biological_process	carbon utilization
A	0016829	molecular_function	lyase activity
A	0034599	biological_process	cellular response to oxidative stress
A	0046872	molecular_function	metal ion binding
A	0071244	biological_process	cellular response to carbon dioxide
B	0004089	molecular_function	carbonate dehydratase activity
B	0005737	cellular_component	cytoplasm
B	0008270	molecular_function	zinc ion binding
B	0015976	biological_process	carbon utilization
B	0016829	molecular_function	lyase activity
B	0034599	biological_process	cellular response to oxidative stress
B	0046872	molecular_function	metal ion binding
B	0071244	biological_process	cellular response to carbon dioxide
C	0004089	molecular_function	carbonate dehydratase activity
C	0005737	cellular_component	cytoplasm
C	0008270	molecular_function	zinc ion binding
C	0015976	biological_process	carbon utilization
C	0016829	molecular_function	lyase activity
C	0034599	biological_process	cellular response to oxidative stress
C	0046872	molecular_function	metal ion binding
C	0071244	biological_process	cellular response to carbon dioxide
D	0004089	molecular_function	carbonate dehydratase activity
D	0005737	cellular_component	cytoplasm
D	0008270	molecular_function	zinc ion binding
D	0015976	biological_process	carbon utilization
D	0016829	molecular_function	lyase activity
D	0034599	biological_process	cellular response to oxidative stress
D	0046872	molecular_function	metal ion binding
D	0071244	biological_process	cellular response to carbon dioxide
E	0004089	molecular_function	carbonate dehydratase activity
E	0005737	cellular_component	cytoplasm
E	0008270	molecular_function	zinc ion binding
E	0015976	biological_process	carbon utilization
E	0016829	molecular_function	lyase activity
E	0034599	biological_process	cellular response to oxidative stress
E	0046872	molecular_function	metal ion binding
E	0071244	biological_process	cellular response to carbon dioxide
F	0004089	molecular_function	carbonate dehydratase activity
F	0005737	cellular_component	cytoplasm
F	0008270	molecular_function	zinc ion binding
F	0015976	biological_process	carbon utilization
F	0016829	molecular_function	lyase activity
F	0034599	biological_process	cellular response to oxidative stress
F	0046872	molecular_function	metal ion binding
F	0071244	biological_process	cellular response to carbon dioxide
G	0004089	molecular_function	carbonate dehydratase activity
G	0005737	cellular_component	cytoplasm
G	0008270	molecular_function	zinc ion binding
G	0015976	biological_process	carbon utilization
G	0016829	molecular_function	lyase activity
G	0034599	biological_process	cellular response to oxidative stress
G	0046872	molecular_function	metal ion binding
G	0071244	biological_process	cellular response to carbon dioxide
H	0004089	molecular_function	carbonate dehydratase activity
H	0005737	cellular_component	cytoplasm
H	0008270	molecular_function	zinc ion binding
H	0015976	biological_process	carbon utilization
H	0016829	molecular_function	lyase activity
H	0034599	biological_process	cellular response to oxidative stress
H	0046872	molecular_function	metal ion binding
H	0071244	biological_process	cellular response to carbon dioxide

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue ZN A 301

Chain	Residue
A	CYS42
A	ASP44
A	HIS98
A	CYS101

site_id	AC2
Number of Residues	7
Details	binding site for residue BCT A 302

Chain	Residue
A	TYR181
A	HOH423
A	TRP39
A	VAL47
A	ALA49
A	ARG64
A	CYS96

site_id	AC3
Number of Residues	4
Details	binding site for residue ZN B 301

Chain	Residue
B	CYS42
B	ASP44
B	HIS98
B	CYS101

site_id	AC4
Number of Residues	9
Details	binding site for residue BCT B 302

Chain	Residue
B	TRP39
B	GLY41
B	VAL47
B	ALA49
B	LEU52
B	ARG64
B	TYR181
B	HOH410
B	HOH467

site_id	AC5
Number of Residues	4
Details	binding site for residue ZN H 301

Chain	Residue
H	CYS42
H	ASP44
H	HIS98
H	CYS101

site_id	AC6
Number of Residues	9
Details	binding site for residue BCT H 302

Chain	Residue
H	TRP39
H	GLY41
H	VAL47
H	PRO48
H	ALA49
H	LEU52
H	ARG64
H	TYR181
H	HOH464

site_id	AC7
Number of Residues	4
Details	binding site for residue ZN G 301

Chain	Residue
G	CYS42
G	ASP44
G	HIS98
G	CYS101

site_id	AC8
Number of Residues	9
Details	binding site for residue BCT G 302

Chain	Residue
G	TRP39
G	GLY41
G	VAL47
G	PRO48
G	ALA49
G	ARG64
G	TYR181
G	HOH438
G	HOH444

site_id	AC9
Number of Residues	4
Details	binding site for residue ZN D 301

Chain	Residue
D	CYS42
D	ASP44
D	HIS98
D	CYS101

site_id	AD1
Number of Residues	8
Details	binding site for residue BCT D 302

Chain	Residue
D	TRP39
D	VAL47
D	ALA49
D	LEU52
D	ARG64
D	TYR181
D	HOH413
D	HOH416

site_id	AD2
Number of Residues	4
Details	binding site for residue ZN C 301

Chain	Residue
C	CYS42
C	ASP44
C	HIS98
C	CYS101

site_id	AD3
Number of Residues	8
Details	binding site for residue BCT C 302

Chain	Residue
C	TRP39
C	GLY41
C	VAL47
C	ALA49
C	ARG64
C	TYR181
C	HOH412
C	HOH425

site_id	AD4
Number of Residues	4
Details	binding site for residue ZN F 301

Chain	Residue
F	CYS42
F	ASP44
F	HIS98
F	CYS101

site_id	AD5
Number of Residues	4
Details	binding site for residue ZN E 301

Chain	Residue
E	CYS42
E	ASP44
E	HIS98
E	CYS101

Functional Information from PROSITE/UniProt

site_id	PS00704
Number of Residues	8
Details	PROK_CO2_ANHYDRASE_1 Prokaryotic-type carbonic anhydrases signature 1. CADSRVpA

Chain	Residue	Details
A	CYS42-ALA49

site_id	PS00705
Number of Residues	21
Details	PROK_CO2_ANHYDRASE_2 Prokaryotic-type carbonic anhydrases signature 2. QYAVdvLqvkhIIVcGHygCG

Chain	Residue	Details
A	GLN82-GLY102

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)