5CXG

Crystal structure of Mycobacterium tuberculosis KstR in complex with PEG

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000976	molecular_function	transcription cis-regulatory region binding
A	0003677	molecular_function	DNA binding
A	0003700	molecular_function	DNA-binding transcription factor activity
A	0006351	biological_process	DNA-templated transcription
A	0006355	biological_process	regulation of DNA-templated transcription
A	0042803	molecular_function	protein homodimerization activity
B	0000976	molecular_function	transcription cis-regulatory region binding
B	0003677	molecular_function	DNA binding
B	0003700	molecular_function	DNA-binding transcription factor activity
B	0006351	biological_process	DNA-templated transcription
B	0006355	biological_process	regulation of DNA-templated transcription
B	0042803	molecular_function	protein homodimerization activity
C	0000976	molecular_function	transcription cis-regulatory region binding
C	0003677	molecular_function	DNA binding
C	0003700	molecular_function	DNA-binding transcription factor activity
C	0006351	biological_process	DNA-templated transcription
C	0006355	biological_process	regulation of DNA-templated transcription
C	0042803	molecular_function	protein homodimerization activity
D	0000976	molecular_function	transcription cis-regulatory region binding
D	0003677	molecular_function	DNA binding
D	0003700	molecular_function	DNA-binding transcription factor activity
D	0006351	biological_process	DNA-templated transcription
D	0006355	biological_process	regulation of DNA-templated transcription
D	0042803	molecular_function	protein homodimerization activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	binding site for residue PGE A 201

Chain	Residue
A	LEU68
A	PHE72
A	MET104
A	THR115
A	TRP164
A	LEU168

---

site_id	AC2
Number of Residues	2
Details	binding site for residue PGE B 201

Chain	Residue
B	TRP171
B	LEU172

---

site_id	AC3
Number of Residues	4
Details	binding site for residue PEG C 201

Chain	Residue
C	TRP171
C	LEU172
C	ARG174
C	PRO108

---

site_id	AC4
Number of Residues	5
Details	binding site for residue PGE C 202

Chain	Residue
C	LEU68
C	THR115
C	TYR118
C	TRP164
C	LEU168

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	240
Details	Domain: {"description":"HTH tetR-type","evidences":[{"source":"PROSITE-ProRule","id":"PRU00335","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	76
Details	DNA binding: {"description":"H-T-H motif","evidences":[{"source":"PROSITE-ProRule","id":"PRU00335","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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