5CW8
Crystal structure of Mycobacterium tuberculosis KstR in complex with 3-oxo-4-cholesten-26-oyl-CoA
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000976 | molecular_function | transcription cis-regulatory region binding |
| A | 0003677 | molecular_function | DNA binding |
| A | 0003700 | molecular_function | DNA-binding transcription factor activity |
| A | 0006351 | biological_process | DNA-templated transcription |
| A | 0006355 | biological_process | regulation of DNA-templated transcription |
| A | 0042803 | molecular_function | protein homodimerization activity |
| B | 0000976 | molecular_function | transcription cis-regulatory region binding |
| B | 0003677 | molecular_function | DNA binding |
| B | 0003700 | molecular_function | DNA-binding transcription factor activity |
| B | 0006351 | biological_process | DNA-templated transcription |
| B | 0006355 | biological_process | regulation of DNA-templated transcription |
| B | 0042803 | molecular_function | protein homodimerization activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 11 |
| Details | binding site for residue 55X A 201 |
| Chain | Residue |
| A | GLU71 |
| A | SER161 |
| A | TRP164 |
| A | PHE72 |
| A | LEU100 |
| A | ALA103 |
| A | MET104 |
| A | ASN107 |
| A | MET114 |
| A | TYR118 |
| A | ARG158 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue 55X B 201 |
| Chain | Residue |
| B | THR111 |
| B | ILE136 |
| B | ARG158 |
| B | SER161 |
| B | TRP164 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | binding site for residue PGE B 202 |
| Chain | Residue |
| A | GLU148 |
| A | PRO149 |
| A | TYR154 |
| B | PRO108 |
| B | TRP171 |
| B | LEU172 |
| B | ARG174 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 120 |
| Details | Domain: {"description":"HTH tetR-type","evidences":[{"source":"PROSITE-ProRule","id":"PRU00335","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 38 |
| Details | DNA binding: {"description":"H-T-H motif","evidences":[{"source":"PROSITE-ProRule","id":"PRU00335","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
