5CUY
Crystal structure of Trypanosoma brucei Vacuolar Soluble Pyrophosphatases in apo form
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000287 | molecular_function | magnesium ion binding |
| A | 0004427 | molecular_function | inorganic diphosphate phosphatase activity |
| A | 0005509 | molecular_function | calcium ion binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006796 | biological_process | phosphate-containing compound metabolic process |
| A | 0008270 | molecular_function | zinc ion binding |
| A | 0016462 | molecular_function | pyrophosphatase activity |
| A | 0020022 | cellular_component | acidocalcisome |
| B | 0000287 | molecular_function | magnesium ion binding |
| B | 0004427 | molecular_function | inorganic diphosphate phosphatase activity |
| B | 0005509 | molecular_function | calcium ion binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0006796 | biological_process | phosphate-containing compound metabolic process |
| B | 0008270 | molecular_function | zinc ion binding |
| B | 0016462 | molecular_function | pyrophosphatase activity |
| B | 0020022 | cellular_component | acidocalcisome |
| C | 0000287 | molecular_function | magnesium ion binding |
| C | 0004427 | molecular_function | inorganic diphosphate phosphatase activity |
| C | 0005509 | molecular_function | calcium ion binding |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0006796 | biological_process | phosphate-containing compound metabolic process |
| C | 0008270 | molecular_function | zinc ion binding |
| C | 0016462 | molecular_function | pyrophosphatase activity |
| C | 0020022 | cellular_component | acidocalcisome |
| D | 0000287 | molecular_function | magnesium ion binding |
| D | 0004427 | molecular_function | inorganic diphosphate phosphatase activity |
| D | 0005509 | molecular_function | calcium ion binding |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0006796 | biological_process | phosphate-containing compound metabolic process |
| D | 0008270 | molecular_function | zinc ion binding |
| D | 0016462 | molecular_function | pyrophosphatase activity |
| D | 0020022 | cellular_component | acidocalcisome |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 8 |
| Details | binding site for residue CIT A 901 |
| Chain | Residue |
| A | ARG213 |
| A | LYS215 |
| A | THR219 |
| A | MET221 |
| A | ASN222 |
| A | ARG223 |
| A | LYS314 |
| A | HIS336 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue MG A 902 |
| Chain | Residue |
| A | PRO294 |
| A | ASP296 |
| A | ASP328 |
| A | ASP291 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | binding site for residue CIT B 901 |
| Chain | Residue |
| B | ARG213 |
| B | LYS215 |
| B | THR219 |
| B | PRO220 |
| B | ASN222 |
| B | ARG223 |
| B | HIS336 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue MG B 902 |
| Chain | Residue |
| B | ASP296 |
| B | ASP328 |
| B | HOH1025 |
| B | HOH1036 |
| B | HOH1050 |
| B | HOH1094 |
| site_id | AC5 |
| Number of Residues | 10 |
| Details | binding site for residue CIT C 901 |
| Chain | Residue |
| C | ARG213 |
| C | LYS215 |
| C | THR219 |
| C | PRO220 |
| C | MET221 |
| C | ASN222 |
| C | ARG223 |
| C | LYS314 |
| C | HIS336 |
| C | HOH1057 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | binding site for residue MG C 902 |
| Chain | Residue |
| C | ASP291 |
| C | ASP296 |
| C | ASP328 |
| C | HOH1080 |
| site_id | AC7 |
| Number of Residues | 10 |
| Details | binding site for residue CIT D 901 |
| Chain | Residue |
| D | ARG213 |
| D | LYS215 |
| D | THR219 |
| D | PRO220 |
| D | MET221 |
| D | ASN222 |
| D | ARG223 |
| D | HIS336 |
| D | HOH1017 |
| D | HOH1075 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | binding site for residue MG D 902 |
| Chain | Residue |
| D | ASP291 |
| D | ASP296 |
| D | ASP328 |
Functional Information from PROSITE/UniProt
| site_id | PS00387 |
| Number of Residues | 7 |
| Details | PPASE Inorganic pyrophosphatase signature. DNDPVDA |
| Chain | Residue | Details |
| A | ASP291-ALA297 |
