5CUM

Crystal structure of Human Defensin-5 Y27A mutant crystal form 1.

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005576	cellular_component	extracellular region
A	0006952	biological_process	defense response
B	0005576	cellular_component	extracellular region
B	0006952	biological_process	defense response
C	0005576	cellular_component	extracellular region
C	0006952	biological_process	defense response

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	binding site for residue CA A 101

Chain	Residue
A	GLU21
A	GLY24
B	GLU21
B	GLY24
C	GLU21
C	GLY24

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site_id	AC2
Number of Residues	2
Details	binding site for residue CL A 102

Chain	Residue
A	ARG6
A	THR7

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site_id	AC3
Number of Residues	1
Details	binding site for residue CL A 104

Chain	Residue
A	CYS10

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site_id	AC4
Number of Residues	2
Details	binding site for residue CL A 105

Chain	Residue
A	ARG9
A	ARG28

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site_id	AC5
Number of Residues	3
Details	binding site for residue IPA A 106

Chain	Residue
A	CYS3
A	CYS5
A	HOH217

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site_id	AC6
Number of Residues	2
Details	binding site for residue CL B 101

Chain	Residue
B	CYS10
B	HOH208

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site_id	AC7
Number of Residues	2
Details	binding site for residue IPA B 102

Chain	Residue
B	CYS5
B	HOH216

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site_id	AC8
Number of Residues	2
Details	binding site for residue CL C 101

Chain	Residue
C	ARG6
C	THR7

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Functional Information from PROSITE/UniProt

site_id	PS00269
Number of Residues	29
Details	DEFENSIN Mammalian defensins signature. CyCrtgr.CatreslsGvCeisgrlarlCC

Chain	Residue	Details
A	CYS3-CYS31

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	93
Details	Peptide: {"description":"HD5(63-94)","featureId":"PRO_0000417390","evidences":[{"source":"PubMed","id":"12021776","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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