5CUJ

Crystal structure of Human Defensin-5 Y27A mutant crystal form 2.

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005576	cellular_component	extracellular region
A	0006952	biological_process	defense response
B	0005576	cellular_component	extracellular region
B	0006952	biological_process	defense response
C	0005576	cellular_component	extracellular region
C	0006952	biological_process	defense response
D	0005576	cellular_component	extracellular region
D	0006952	biological_process	defense response
E	0005576	cellular_component	extracellular region
E	0006952	biological_process	defense response
F	0005576	cellular_component	extracellular region
F	0006952	biological_process	defense response

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	binding site for residue CA A 101

Chain	Residue
A	GLU21
A	GLY24
E	GLU21
E	GLY24
F	GLU21
F	GLY24

---

site_id	AC2
Number of Residues	4
Details	binding site for residue CL A 102

Chain	Residue
E	THR7
A	ARG6
A	THR7
E	ARG6

---

site_id	AC3
Number of Residues	6
Details	binding site for residue CA B 101

Chain	Residue
B	GLU21
B	GLY24
C	GLU21
C	GLY24
D	GLU21
D	GLY24

---

site_id	AC4
Number of Residues	6
Details	binding site for residue CL B 102

Chain	Residue
B	ARG6
B	ARG6
B	THR7
B	THR7
B	GLY8
B	GLY8

---

site_id	AC5
Number of Residues	1
Details	binding site for residue CL B 103

Chain	Residue
E	CL102

---

site_id	AC6
Number of Residues	6
Details	binding site for residue CL C 101

Chain	Residue
C	ARG6
C	THR7
C	GLY8
D	ARG6
D	THR7
D	GLY8

---

site_id	AC7
Number of Residues	2
Details	binding site for residue MPD C 103

Chain	Residue
C	ALA1
C	SER17

---

site_id	AC8
Number of Residues	4
Details	binding site for residue CL D 101

Chain	Residue
C	ARG6
C	THR7
D	ARG6
D	THR7

---

site_id	AC9
Number of Residues	2
Details	binding site for residue CL D 102

Chain	Residue
D	ARG28
F	LEU16

---

site_id	AD1
Number of Residues	2
Details	binding site for residue MPD D 103

Chain	Residue
B	ARG32
D	ARG32

---

site_id	AD2
Number of Residues	4
Details	binding site for residue CL E 101

Chain	Residue
A	ARG6
A	THR7
E	ARG6
E	THR7

---

site_id	AD3
Number of Residues	1
Details	binding site for residue CL E 102

Chain	Residue
B	CL103

---

site_id	AD4
Number of Residues	4
Details	binding site for residue CL F 101

Chain	Residue
F	ARG6
F	ARG6
F	THR7
F	THR7

---

site_id	AD5
Number of Residues	4
Details	binding site for residue MPD F 103

Chain	Residue
E	ALA1
E	ARG32
F	ALA1
F	ARG32

---

Functional Information from PROSITE/UniProt

site_id	PS00269
Number of Residues	29
Details	DEFENSIN Mammalian defensins signature. CyCrtgr.CatreslsGvCeisgrlarlCC

Chain	Residue	Details
A	CYS3-CYS31

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	186
Details	Peptide: {"description":"HD5(63-94)","featureId":"PRO_0000417390","evidences":[{"source":"PubMed","id":"12021776","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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