5CU8
Crystal structure of the bromodomain of bromodomain adjacent to zinc finger domain protein 2B (BAZ2B) in complex with 2-Amino-6-chlorobenzothiazole (SGC - Diamond I04-1 fragment screening)
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 10 |
| Details | binding site for residue 54T A 2001 |
| Chain | Residue |
| A | PRO1888 |
| A | HOH2173 |
| A | PHE1889 |
| A | VAL1893 |
| A | PRO1899 |
| A | PHE1943 |
| A | ASN1944 |
| A | ILE1950 |
| A | 54T2002 |
| A | HOH2117 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue 54T A 2002 |
| Chain | Residue |
| A | LEU1891 |
| A | PRO1892 |
| A | 54T2001 |
| A | HOH2105 |
| A | HOH2136 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 2003 |
| Chain | Residue |
| A | MET1875 |
| A | GLU1879 |
| A | LYS1964 |
| A | THR1968 |
| A | HOH2157 |
Functional Information from PROSITE/UniProt
| site_id | PS00633 |
| Number of Residues | 58 |
| Details | BROMODOMAIN_1 Bromodomain signature. AwpFllpvNlklvp..GYKkvIkkpMdfstIreklssgq..Ypnletfaldvrl.VfdNCetF |
| Chain | Residue | Details |
| A | ALA1886-PHE1943 |
