5CRD
Wild-type human skeletal calsequestrin
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005509 | molecular_function | calcium ion binding |
| A | 0005515 | molecular_function | protein binding |
| A | 0005739 | cellular_component | mitochondrion |
| A | 0005759 | cellular_component | mitochondrial matrix |
| A | 0005783 | cellular_component | endoplasmic reticulum |
| A | 0005790 | cellular_component | smooth endoplasmic reticulum |
| A | 0007519 | biological_process | skeletal muscle tissue development |
| A | 0014802 | cellular_component | terminal cisterna |
| A | 0014804 | cellular_component | terminal cisterna lumen |
| A | 0014809 | biological_process | regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion |
| A | 0014870 | biological_process | response to muscle inactivity |
| A | 0014894 | biological_process | response to denervation involved in regulation of muscle adaptation |
| A | 0016529 | cellular_component | sarcoplasmic reticulum |
| A | 0030016 | cellular_component | myofibril |
| A | 0030018 | cellular_component | Z disc |
| A | 0030315 | cellular_component | T-tubule |
| A | 0031674 | cellular_component | I band |
| A | 0033017 | cellular_component | sarcoplasmic reticulum membrane |
| A | 0033018 | cellular_component | sarcoplasmic reticulum lumen |
| A | 0042383 | cellular_component | sarcolemma |
| A | 0042802 | molecular_function | identical protein binding |
| A | 0045214 | biological_process | sarcomere organization |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0051258 | biological_process | protein polymerization |
| A | 0051279 | biological_process | regulation of release of sequestered calcium ion into cytosol |
| A | 0051281 | biological_process | positive regulation of release of sequestered calcium ion into cytosol |
| A | 0051282 | biological_process | regulation of sequestering of calcium ion |
| A | 1901341 | biological_process | positive regulation of store-operated calcium channel activity |
| A | 2001256 | biological_process | regulation of store-operated calcium entry |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | binding site for residue CA A 401 |
| Chain | Residue |
| A | ASN17 |
| A | VAL18 |
| A | LEU74 |
| A | ASP80 |
| A | HOH555 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue CA A 402 |
| Chain | Residue |
| A | GLU199 |
| A | THR229 |
| A | THR277 |
| A | HOH693 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue CA A 403 |
| Chain | Residue |
| A | ASP210 |
| A | PRO212 |
| A | GLU217 |
| A | HOH503 |
| A | HOH678 |
| site_id | AC4 |
| Number of Residues | 2 |
| Details | binding site for residue CA A 404 |
| Chain | Residue |
| A | THR189 |
| A | HOH630 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | binding site for residue MPD A 405 |
| Chain | Residue |
| A | PRO7 |
| A | GLU8 |
| A | GLN63 |
| A | LEU294 |
| A | LEU295 |
| A | HOH571 |
| A | HOH668 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | binding site for residue MPD A 406 |
| Chain | Residue |
| A | PHE6 |
| A | TRP242 |
| A | TYR298 |
| A | TRP299 |
Functional Information from PROSITE/UniProt
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"UniProtKB","id":"P19633","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"P19633","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"UniProtKB","id":"P19633","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
