5CR6

Structure of pneumolysin at 1.98 A resolution

Functional Information from GO Data

Chain	GOid	namespace	contents
D	0005576	cellular_component	extracellular region
D	0015485	molecular_function	cholesterol binding
D	0020002	cellular_component	host cell plasma membrane
D	0141060	biological_process	disruption of anatomical structure in another organism

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	43
Details	Transmembrane: {"description":"Beta stranded","evidences":[{"source":"PubMed","id":"28323617","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5LY6","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	10
Details	Motif: {"description":"Conserved undecapeptide","evidences":[{"evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	1
Details	Motif: {"description":"Cholesterol binding","evidences":[{"source":"PubMed","id":"20145114","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---