5CQ7

Crystal structure of the bromodomain of bromodomain adjacent to zinc finger domain protein 2B (BAZ2B) in complex with N,N-dimethylquinoxaline-6-carboxamide (SGC - Diamond I04-1 fragment screening)

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	binding site for residue 53G A 2001

Chain	Residue
A	PRO1888
A	VAL1898
A	PRO1899
A	ASN1944
A	HOH2117

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site_id	AC2
Number of Residues	4
Details	binding site for residue EDO A 2002

Chain	Residue
A	MET1875
A	GLU1879
A	LYS1964
A	THR1968

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Functional Information from PROSITE/UniProt

site_id	PS00633
Number of Residues	58
Details	BROMODOMAIN_1 Bromodomain signature. AwpFllpvNlklvp..GYKkvIkkpMdfstIreklssgq..Ypnletfaldvrl.VfdNCetF

Chain	Residue	Details
A	ALA1886-PHE1943

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:21406692

Chain	Residue	Details
A	LEU1918

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site_id	SWS_FT_FI2
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:21406692

Chain	Residue	Details
A	TYR1923

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