5CMK
Crystal structure of the GluK2EM LBD dimer assembly complex with glutamate and LY466195
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 13 |
| Details | binding site for residue GLU A 301 |
| Chain | Residue |
| A | TYR61 |
| A | HOH414 |
| A | HOH437 |
| A | HOH448 |
| A | HOH496 |
| A | PRO89 |
| A | LEU90 |
| A | THR91 |
| A | ARG96 |
| A | GLY141 |
| A | SER142 |
| A | THR143 |
| A | GLU191 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue LI A 302 |
| Chain | Residue |
| A | GLU97 |
| A | ILE100 |
| A | ASP101 |
| A | HOH410 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue CL A 303 |
| Chain | Residue |
| A | LYS104 |
| A | HOH434 |
| B | LYS104 |
| B | HOH468 |
| site_id | AC4 |
| Number of Residues | 15 |
| Details | binding site for residue LY5 B 301 |
| Chain | Residue |
| B | TYR61 |
| B | PRO89 |
| B | LEU90 |
| B | THR91 |
| B | ARG96 |
| B | GLY141 |
| B | SER142 |
| B | THR143 |
| B | SER174 |
| B | MET190 |
| B | GLU191 |
| B | TYR217 |
| B | HOH515 |
| B | HOH532 |
| B | HOH568 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | binding site for residue LI B 302 |
| Chain | Residue |
| B | GLU97 |
| B | ILE100 |
| B | ASP101 |
| B | HOH418 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 B 303 |
| Chain | Residue |
| A | ARG201 |
| B | PRO25 |
| B | LEU26 |
| B | HOH405 |
| B | HOH433 |
| B | HOH605 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 B 304 |
| Chain | Residue |
| A | ARG31 |
| A | ARG54 |
| A | LEU55 |
| B | GLU57 |
| B | HOH490 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | binding site for residue CL B 305 |
| Chain | Residue |
| A | LYS60 |
| A | LYS172 |
| B | ASN3 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 12 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"15721240","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17115050","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1S50","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1S7Y","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2I0B","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2I0C","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"15677325","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"8163463","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
