5CLW

Crystal structure of human glycogen branching enzyme (GBE1) in complex with maltoheptaose

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003824	molecular_function	catalytic activity
A	0003844	molecular_function	1,4-alpha-glucan branching enzyme activity
A	0004553	molecular_function	hydrolase activity, hydrolyzing O-glycosyl compounds
A	0005515	molecular_function	protein binding
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0005975	biological_process	carbohydrate metabolic process
A	0005977	biological_process	glycogen metabolic process
A	0005978	biological_process	glycogen biosynthetic process
A	0006091	biological_process	generation of precursor metabolites and energy
A	0016740	molecular_function	transferase activity
A	0016757	molecular_function	glycosyltransferase activity
A	0030246	molecular_function	carbohydrate binding
A	0043169	molecular_function	cation binding
A	0043524	biological_process	negative regulation of neuron apoptotic process
A	0070062	cellular_component	extracellular exosome
B	0003824	molecular_function	catalytic activity
B	0003844	molecular_function	1,4-alpha-glucan branching enzyme activity
B	0004553	molecular_function	hydrolase activity, hydrolyzing O-glycosyl compounds
B	0005515	molecular_function	protein binding
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0005975	biological_process	carbohydrate metabolic process
B	0005977	biological_process	glycogen metabolic process
B	0005978	biological_process	glycogen biosynthetic process
B	0006091	biological_process	generation of precursor metabolites and energy
B	0016740	molecular_function	transferase activity
B	0016757	molecular_function	glycosyltransferase activity
B	0030246	molecular_function	carbohydrate binding
B	0043169	molecular_function	cation binding
B	0043524	biological_process	negative regulation of neuron apoptotic process
B	0070062	cellular_component	extracellular exosome
C	0003824	molecular_function	catalytic activity
C	0003844	molecular_function	1,4-alpha-glucan branching enzyme activity
C	0004553	molecular_function	hydrolase activity, hydrolyzing O-glycosyl compounds
C	0005515	molecular_function	protein binding
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0005975	biological_process	carbohydrate metabolic process
C	0005977	biological_process	glycogen metabolic process
C	0005978	biological_process	glycogen biosynthetic process
C	0006091	biological_process	generation of precursor metabolites and energy
C	0016740	molecular_function	transferase activity
C	0016757	molecular_function	glycosyltransferase activity
C	0030246	molecular_function	carbohydrate binding
C	0043169	molecular_function	cation binding
C	0043524	biological_process	negative regulation of neuron apoptotic process
C	0070062	cellular_component	extracellular exosome

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	3
Details	Active site: {"description":"Nucleophile","evidences":[{"source":"PubMed","id":"26199317","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	3
Details	Active site: {"description":"Proton donor","evidences":[{"source":"PubMed","id":"26199317","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	27
Details	Binding site: {"evidences":[{"source":"PubMed","id":"26199317","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"5CLT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5CLW","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	6
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"Q6FJV0","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	3
Details	Site: {"description":"Transition state stabilizer","evidences":[{"source":"PubMed","id":"26199317","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	3
Details	Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"PubMed","id":"15592455","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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