5CFR

Crystal structure of anemone STING (Nematostella vectensis) in apo 'unrotated' closed conformation

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0002218	biological_process	activation of innate immune response
A	0032481	biological_process	positive regulation of type I interferon production
B	0002218	biological_process	activation of innate immune response
B	0032481	biological_process	positive regulation of type I interferon production

Functional Information from PDB Data

site_id	AC1
Number of Residues	3
Details	binding site for residue CA A 401

Chain	Residue
A	SER226
A	GLN256
A	ASP337

---

site_id	AC2
Number of Residues	3
Details	binding site for residue CA A 402

Chain	Residue
A	ASP254
A	ASN257
A	ILE259

---

site_id	AC3
Number of Residues	3
Details	binding site for residue CA B 401

Chain	Residue
B	ASP254
B	ASN257
B	ILE259

---

site_id	AC4
Number of Residues	3
Details	binding site for residue CA B 402

Chain	Residue
B	SER226
B	GLN256
B	ASP337

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"26300263","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5CFL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5CFP","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	10
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"Q86WV6","evidenceCode":"ECO:0000250"},{"source":"PubMed","id":"26300263","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5CFL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5CFP","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"26300263","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5CFQ","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---