5CFR
Crystal structure of anemone STING (Nematostella vectensis) in apo 'unrotated' closed conformation
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0002218 | biological_process | activation of innate immune response |
| A | 0032481 | biological_process | positive regulation of type I interferon production |
| B | 0002218 | biological_process | activation of innate immune response |
| B | 0032481 | biological_process | positive regulation of type I interferon production |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | binding site for residue CA A 401 |
| Chain | Residue |
| A | SER226 |
| A | GLN256 |
| A | ASP337 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | binding site for residue CA A 402 |
| Chain | Residue |
| A | ASP254 |
| A | ASN257 |
| A | ILE259 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | binding site for residue CA B 401 |
| Chain | Residue |
| B | ASP254 |
| B | ASN257 |
| B | ILE259 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | binding site for residue CA B 402 |
| Chain | Residue |
| B | SER226 |
| B | GLN256 |
| B | ASP337 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:26300263, ECO:0007744|PDB:5CFL, ECO:0007744|PDB:5CFP |
| Chain | Residue | Details |
| A | TYR206 | |
| B | TYR206 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 6 |
| Details | BINDING: BINDING => ECO:0000250|UniProtKB:Q86WV6, ECO:0000269|PubMed:26300263, ECO:0007744|PDB:5CFL, ECO:0007744|PDB:5CFP |
| Chain | Residue | Details |
| A | ARG272 | |
| A | ARG278 | |
| A | GLU300 | |
| B | ARG272 | |
| B | ARG278 | |
| B | GLU300 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:26300263, ECO:0007744|PDB:5CFQ |
| Chain | Residue | Details |
| A | THR303 | |
| B | THR303 |
