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5CFJ

Structural and functional attributes of malaria parasite Ap4A hydrolase

Functional Information from GO Data
ChainGOidnamespacecontents
A0000166molecular_functionnucleotide binding
A0004081molecular_functionbis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity
A0006167biological_processAMP biosynthetic process
A0006754biological_processATP biosynthetic process
A0008796molecular_functionbis(5'-nucleosyl)-tetraphosphatase activity
A0016787molecular_functionhydrolase activity
Functional Information from PDB Data
site_idAC1
Number of Residues5
Detailsbinding site for residue SO4 A 201
ChainResidue
AHIS43
ALYS48
ATYR87
ALYS94
AHOH307

site_idAC2
Number of Residues7
Detailsbinding site for residue SO4 A 202
ChainResidue
AHIS125
ALYS141
AHOH309
AASN28
ALYS36
ALYS42
ATRP44

site_idAC3
Number of Residues5
Detailsbinding site for residue SO4 A 203
ChainResidue
AARG15
ATYR119
ATRP121
AHOH321
AHOH389

site_idAC4
Number of Residues4
Detailsbinding site for residue PEG A 204
ChainResidue
ALEU66
AGLY70
ALYS77
AHOH338

Functional Information from PROSITE/UniProt
site_idPS00893
Number of Residues22
DetailsNUDIX_BOX Nudix box signature. GlhennEsgleTAvRETlEEtG
ChainResidueDetails
AGLY49-GLY70

226707

PDB entries from 2024-10-30

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