Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003677 | molecular_function | DNA binding |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0003906 | molecular_function | DNA-(apurinic or apyrimidinic site) endonuclease activity |
| A | 0004518 | molecular_function | nuclease activity |
| A | 0004519 | molecular_function | endonuclease activity |
| A | 0004527 | molecular_function | exonuclease activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006281 | biological_process | DNA repair |
| A | 0006284 | biological_process | base-excision repair |
| A | 0008081 | molecular_function | phosphoric diester hydrolase activity |
| A | 0008311 | molecular_function | double-stranded DNA 3'-5' DNA exonuclease activity |
| A | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue CA A 301 |
| Chain | Residue |
| A | ASN9 |
| A | GLU36 |
| A | HOH415 |
| A | HOH462 |
| A | HOH529 |
| A | HOH557 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | binding site for residue PEG A 302 |
| Chain | Residue |
| A | GLU133 |
| A | LEU134 |
| A | LYS137 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue PEG A 303 |
| Chain | Residue |
| A | ILE78 |
| A | TYR79 |
| A | ILE81 |
| A | GLY82 |
| A | HOH404 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | binding site for residue PEG A 304 |
| Chain | Residue |
| A | ALA165 |
| A | TRP200 |
| A | TRP214 |
| A | HOH417 |
| A | HOH418 |
| A | HOH465 |
| A | HOH484 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | binding site for residue CA A 305 |
| Chain | Residue |
| A | GLU27 |
| A | GLU98 |
| A | GLU247 |
| A | HOH514 |
| A | HOH549 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | binding site for residue CA A 306 |
| Chain | Residue |
| A | GLU195 |
| A | HOH548 |
| A | HOH562 |
| A | HOH572 |
Functional Information from PROSITE/UniProt
| site_id | PS00726 |
| Number of Residues | 10 |
| Details | AP_NUCLEASE_F1_1 AP endonucleases family 1 signature 1. ADIICLQETK |
| Chain | Residue | Details |
| A | ALA29-LYS38 | |
| site_id | PS00727 |
| Number of Residues | 17 |
| Details | AP_NUCLEASE_F1_2 AP endonucleases family 1 signature 2. DSFRHvypdlegaYSWW |
| Chain | Residue | Details |
| A | ASP185-TRP201 | |
| site_id | PS00728 |
| Number of Residues | 12 |
| Details | AP_NUCLEASE_F1_3 AP endonucleases family 1 signature 3. NiGwRIDYfVvS |
| Chain | Residue | Details |
| A | ASN211-SER222 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | ACT_SITE: ACT_SITE => ECO:0000250 |
| Chain | Residue | Details |
| A | TYR106 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | ACT_SITE: Proton donor/acceptor => ECO:0000250 |
| Chain | Residue | Details |
| A | ASP145 | |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000250 |
| Chain | Residue | Details |
| A | ASN147 | |
| A | ASP242 | |
| A | GLU36 | |
| A | ASP145 | |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | SITE: Transition state stabilizer => ECO:0000250 |
| Chain | Residue | Details |
| A | ASN147 | |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | SITE: Important for catalytic activity => ECO:0000250 |
| Chain | Residue | Details |
| A | ASP217 | |
| site_id | SWS_FT_FI6 |
| Number of Residues | 1 |
| Details | SITE: Interaction with DNA substrate => ECO:0000250 |
| Chain | Residue | Details |
| A | HIS243 | |
