5CDT

I220V horse liver alcohol dehydrogenase complexed with NAD and pentafluorobenzyl alcohol

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004022	molecular_function	alcohol dehydrogenase (NAD+) activity
A	0004745	molecular_function	all-trans-retinol dehydrogenase (NAD+) activity
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0008270	molecular_function	zinc ion binding
A	0016491	molecular_function	oxidoreductase activity
A	0042572	biological_process	retinol metabolic process
A	0042573	biological_process	retinoic acid metabolic process
A	0046872	molecular_function	metal ion binding
B	0004022	molecular_function	alcohol dehydrogenase (NAD+) activity
B	0004745	molecular_function	all-trans-retinol dehydrogenase (NAD+) activity
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0008270	molecular_function	zinc ion binding
B	0016491	molecular_function	oxidoreductase activity
B	0042572	biological_process	retinol metabolic process
B	0042573	biological_process	retinoic acid metabolic process
B	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	binding site for residue ZN A 401

Chain	Residue
A	CYS46
A	HIS67
A	CYS174
A	NAJ403
A	PFB404

---

site_id	AC2
Number of Residues	4
Details	binding site for residue ZN A 402

Chain	Residue
A	CYS97
A	CYS100
A	CYS103
A	CYS111

---

site_id	AC3
Number of Residues	32
Details	binding site for residue NAJ A 403

Chain	Residue
A	ARG47
A	SER48
A	HIS51
A	CYS174
A	THR178
A	GLY199
A	GLY201
A	GLY202
A	VAL203
A	ASP223
A	ILE224
A	LYS228
A	VAL268
A	ILE269
A	VAL292
A	GLY293
A	VAL294
A	ALA317
A	ILE318
A	PHE319
A	ARG369
A	ZN401
A	PFB404
A	HOH543
A	HOH584
A	HOH590
A	HOH597
A	HOH653
A	HOH689
A	HOH765
A	HOH786
A	HOH794

---

site_id	AC4
Number of Residues	13
Details	binding site for residue PFB A 404

Chain	Residue
A	CYS46
A	SER48
A	LEU57
A	HIS67
A	PHE93
A	LEU116
A	PHE140
A	LEU141
A	CYS174
A	VAL294
A	ZN401
A	NAJ403
B	LEU309

---

site_id	AC5
Number of Residues	8
Details	binding site for residue MRD A 405

Chain	Residue
A	ASP297
A	GLN299
A	LYS338
A	PHE340
A	HOH503
A	HOH556
A	HOH570
A	HOH658

---

site_id	AC6
Number of Residues	6
Details	binding site for residue MRD A 406

Chain	Residue
A	ARG218
A	THR238
A	GLU239
A	HOH515
B	GLU239
B	HOH504

---

site_id	AC7
Number of Residues	5
Details	binding site for residue ZN B 401

Chain	Residue
B	CYS46
B	HIS67
B	CYS174
B	NAJ403
B	PFB404

---

site_id	AC8
Number of Residues	4
Details	binding site for residue ZN B 402

Chain	Residue
B	CYS97
B	CYS100
B	CYS103
B	CYS111

---

site_id	AC9
Number of Residues	32
Details	binding site for residue NAJ B 403

Chain	Residue
B	ZN401
B	PFB404
B	HOH502
B	HOH563
B	HOH589
B	HOH602
B	HOH605
B	HOH734
B	HOH756
B	HOH770
B	ARG47
B	SER48
B	HIS51
B	CYS174
B	THR178
B	GLY199
B	GLY201
B	GLY202
B	VAL203
B	ASP223
B	ILE224
B	LYS228
B	VAL268
B	ILE269
B	VAL292
B	GLY293
B	VAL294
B	ALA317
B	ILE318
B	PHE319
B	LEU362
B	ARG369

---

site_id	AD1
Number of Residues	14
Details	binding site for residue PFB B 404

Chain	Residue
A	LEU309
B	CYS46
B	SER48
B	LEU57
B	HIS67
B	PHE93
B	LEU116
B	PHE140
B	LEU141
B	CYS174
B	VAL294
B	ILE318
B	ZN401
B	NAJ403

---

Functional Information from PROSITE/UniProt

site_id	PS00059
Number of Residues	15
Details	ADH_ZINC Zinc-containing alcohol dehydrogenases signature. GHEaAGIvesiGegV

Chain	Residue	Details
A	GLY66-VAL80

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"15299346","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"178875","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1A71","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1A72","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1ADB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1ADC","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1ADF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1ADG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1AXE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1AXG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1BTO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1HET","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1HLD","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1JU9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1LDE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1LDY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1MG0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1MGO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1N8K","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1N92","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1P1R","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1QLH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1QLJ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1QV6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1QV7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1YE3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2JHG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2OHX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3BTO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3OQ6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4DWV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4DXH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NFH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NFS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NG5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4XD2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5ADH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6ADH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7ADH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8ADH","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	6
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"P06525","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	8
Details	Binding site: {"evidences":[{"source":"PubMed","id":"15299346","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"178875","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1A71","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1A72","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1ADB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1ADC","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1ADF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1ADG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1AXE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1AXG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1BTO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1HET","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1HLD","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1JU9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1LDE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1LDY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1MG0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1MGO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1N8K","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1N92","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1P1R","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1QLH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1QLJ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1QV6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1QV7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1YE3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2JHG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2OHX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2OXI","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3BTO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3OQ6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4DWV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4DXH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NFH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NFS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NG5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4XD2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5ADH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6ADH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7ADH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8ADH","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"15299346","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1A71","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1A72","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1ADB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1ADC","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1ADF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1ADG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1AXE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1AXG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1BTO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1HET","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1HLD","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1JU9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1LDE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1LDY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1MG0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1MGO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1N8K","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1N92","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1P1R","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1QLH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1QLJ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1QV6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1QV7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1YE3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2JHG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2OHX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3BTO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3OQ6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4DWV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4DXH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NFH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NFS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NG5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4XD2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5ADH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6ADH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7ADH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8ADH","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	10
Details	Binding site: {"evidences":[{"source":"PubMed","id":"15299346","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1ADB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1AXE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1BTO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1HET","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1HEU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1HF3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1HLD","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1JU9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1LDE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1LDY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1MG0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1MGO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1N8K","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1N92","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1P1R","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1QV6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1QV7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2JHF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2JHG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2OHX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2OXI","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3BTO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3OQ6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4DWV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4DXH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NFH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4XD2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6ADH","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"15299346","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1A71","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1ADB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1AXE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1AXG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1BTO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1HET","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1HEU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1HF3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1HLD","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1JU9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1LDE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1LDY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1MG0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1MGO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1N8K","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1N92","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1P1R","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1QLH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1QV6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1QV7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2JHF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2JHG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2OHX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2OXI","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3BTO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3OQ6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4DWV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4DXH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NFH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NFS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NG5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4XD2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5ADH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6ADH","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"15299346","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1A71","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1ADB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1AXE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1AXG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1BTO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1HET","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1HEU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1HF3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1HLD","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1JU9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1LDE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1MGO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1N8K","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1N92","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1QLH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2JHF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2JHG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2OHX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2OXI","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3OQ6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4DWV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4DXH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NFH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NFS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NG5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4XD2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5ADH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6ADH","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"15299346","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1A71","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1ADB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1AXE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1AXG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1BTO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1HET","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1HEU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1HF3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1HLD","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1LDE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1LDY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1MG0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1MGO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1N8K","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1N92","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1P1R","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1QLH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1QV6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1QV7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2JHF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2JHG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2OHX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2OXI","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3BTO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3OQ6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4DWV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4DXH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NFH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NFS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NG5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4XD2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6ADH","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI9
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"15299346","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1A71","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1ADB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1AXE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1AXG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1BTO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1HET","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1HEU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1HF3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1HLD","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1LDE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1LDY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1MG0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1MGO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1N8K","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1N92","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1P1R","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1QV6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1QV7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2JHF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2JHG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2OHX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2OXI","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3BTO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3OQ6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4DWV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4DXH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NFH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NFS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NG5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4XD2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6ADH","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI10
Number of Residues	2
Details	Modified residue: {"description":"N-acetylserine","evidences":[{"source":"PubMed","id":"5466062","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

Catalytic Information from CSA

site_id	MCSA1
Number of Residues	5
Details	M-CSA 256

Chain	Residue	Details
A	CYS46	metal ligand
A	SER48	hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor, proton relay
A	HIS51	hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor, proton relay
A	HIS67	metal ligand
A	CYS174	metal ligand

---

site_id	MCSA2
Number of Residues	5
Details	M-CSA 256

Chain	Residue	Details
B	CYS46	metal ligand
B	SER48	hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor, proton relay
B	HIS51	hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor, proton relay
B	HIS67	metal ligand
B	CYS174	metal ligand

---