5CDH
Structure of Legionella pneumophila Histidine Acid Phosphatase complexed with L(+)-tartrate
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003993 | molecular_function | acid phosphatase activity |
| A | 0005764 | cellular_component | lysosome |
| A | 0007040 | biological_process | lysosome organization |
| A | 0030288 | cellular_component | outer membrane-bounded periplasmic space |
| A | 0050308 | molecular_function | sugar-phosphatase activity |
| B | 0003993 | molecular_function | acid phosphatase activity |
| B | 0005764 | cellular_component | lysosome |
| B | 0007040 | biological_process | lysosome organization |
| B | 0030288 | cellular_component | outer membrane-bounded periplasmic space |
| B | 0050308 | molecular_function | sugar-phosphatase activity |
| C | 0003993 | molecular_function | acid phosphatase activity |
| C | 0005764 | cellular_component | lysosome |
| C | 0007040 | biological_process | lysosome organization |
| C | 0030288 | cellular_component | outer membrane-bounded periplasmic space |
| C | 0050308 | molecular_function | sugar-phosphatase activity |
| D | 0003993 | molecular_function | acid phosphatase activity |
| D | 0005764 | cellular_component | lysosome |
| D | 0007040 | biological_process | lysosome organization |
| D | 0030288 | cellular_component | outer membrane-bounded periplasmic space |
| D | 0050308 | molecular_function | sugar-phosphatase activity |
| E | 0003993 | molecular_function | acid phosphatase activity |
| E | 0005764 | cellular_component | lysosome |
| E | 0007040 | biological_process | lysosome organization |
| E | 0030288 | cellular_component | outer membrane-bounded periplasmic space |
| E | 0050308 | molecular_function | sugar-phosphatase activity |
| F | 0003993 | molecular_function | acid phosphatase activity |
| F | 0005764 | cellular_component | lysosome |
| F | 0007040 | biological_process | lysosome organization |
| F | 0030288 | cellular_component | outer membrane-bounded periplasmic space |
| F | 0050308 | molecular_function | sugar-phosphatase activity |
| G | 0003993 | molecular_function | acid phosphatase activity |
| G | 0005764 | cellular_component | lysosome |
| G | 0007040 | biological_process | lysosome organization |
| G | 0030288 | cellular_component | outer membrane-bounded periplasmic space |
| G | 0050308 | molecular_function | sugar-phosphatase activity |
| H | 0003993 | molecular_function | acid phosphatase activity |
| H | 0005764 | cellular_component | lysosome |
| H | 0007040 | biological_process | lysosome organization |
| H | 0030288 | cellular_component | outer membrane-bounded periplasmic space |
| H | 0050308 | molecular_function | sugar-phosphatase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 9 |
| Details | binding site for residue TLA A 401 |
| Chain | Residue |
| A | ARG33 |
| A | HIS34 |
| A | ARG37 |
| A | ARG101 |
| A | HIS280 |
| A | ASP281 |
| A | 1PE403 |
| A | HOH502 |
| A | HOH551 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue 1PE A 402 |
| Chain | Residue |
| A | LYS175 |
| A | GLU178 |
| A | SER232 |
| A | TRP235 |
| site_id | AC3 |
| Number of Residues | 14 |
| Details | binding site for residue 1PE A 403 |
| Chain | Residue |
| A | GLU201 |
| A | HIS205 |
| A | TYR208 |
| A | ALA233 |
| A | GLU234 |
| A | ASP281 |
| A | SER298 |
| A | PRO300 |
| A | TLA401 |
| A | HOH551 |
| A | HOH559 |
| A | HOH597 |
| H | ASP181 |
| H | HOH557 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for residue 1PE A 404 |
| Chain | Residue |
| A | TYR310 |
| A | LYS320 |
| A | PRO327 |
| A | VAL337 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | binding site for residue 1PE A 405 |
| Chain | Residue |
| A | ASP30 |
| A | PHE72 |
| A | LYS75 |
| A | TYR76 |
| A | ASN304 |
| site_id | AC6 |
| Number of Residues | 8 |
| Details | binding site for residue TLA B 401 |
| Chain | Residue |
| B | ARG33 |
| B | HIS34 |
| B | ARG37 |
| B | ILE40 |
| B | ARG101 |
| B | HIS280 |
| B | ASP281 |
| B | HOH640 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | binding site for residue 1PE B 402 |
| Chain | Residue |
| B | GLU171 |
| B | LYS175 |
| B | GLU178 |
| B | SER232 |
| B | TRP235 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | binding site for residue 1PE B 403 |
| Chain | Residue |
| B | ARG158 |
| B | GLN240 |
| B | GLU241 |
| B | TYR250 |
| B | THR282 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | binding site for residue TLA C 401 |
| Chain | Residue |
| C | ARG33 |
| C | HIS34 |
| C | ARG37 |
| C | ARG101 |
| C | HIS280 |
| C | ASP281 |
| site_id | AD1 |
| Number of Residues | 6 |
| Details | binding site for residue 1PE C 402 |
| Chain | Residue |
| C | GLU171 |
| C | GLN174 |
| C | LYS175 |
| C | GLU178 |
| C | SER232 |
| C | TRP235 |
| site_id | AD2 |
| Number of Residues | 6 |
| Details | binding site for residue TLA D 401 |
| Chain | Residue |
| D | ARG33 |
| D | HIS34 |
| D | ARG37 |
| D | ARG101 |
| D | HIS280 |
| D | ASP281 |
| site_id | AD3 |
| Number of Residues | 7 |
| Details | binding site for residue 1PE D 402 |
| Chain | Residue |
| D | ARG158 |
| D | PHE237 |
| D | GLN240 |
| D | GLU241 |
| D | TYR250 |
| D | THR282 |
| D | SER286 |
| site_id | AD4 |
| Number of Residues | 7 |
| Details | binding site for residue TLA E 401 |
| Chain | Residue |
| E | ARG33 |
| E | HIS34 |
| E | ARG37 |
| E | ARG101 |
| E | HIS280 |
| E | ASP281 |
| E | HOH502 |
| site_id | AD5 |
| Number of Residues | 4 |
| Details | binding site for residue 1PE E 402 |
| Chain | Residue |
| E | LYS175 |
| E | GLU178 |
| E | SER232 |
| E | TRP235 |
| site_id | AD6 |
| Number of Residues | 9 |
| Details | binding site for residue 1PE E 403 |
| Chain | Residue |
| A | ASP181 |
| A | HOH574 |
| E | GLU201 |
| E | HIS205 |
| E | TYR208 |
| E | GLU234 |
| E | PHE237 |
| E | SER298 |
| E | PRO300 |
| site_id | AD7 |
| Number of Residues | 2 |
| Details | binding site for residue 1PE E 404 |
| Chain | Residue |
| E | LYS320 |
| E | VAL337 |
| site_id | AD8 |
| Number of Residues | 7 |
| Details | binding site for residue TLA F 401 |
| Chain | Residue |
| F | ARG33 |
| F | HIS34 |
| F | ARG37 |
| F | ARG101 |
| F | HIS280 |
| F | ASP281 |
| F | 1PE402 |
| site_id | AD9 |
| Number of Residues | 9 |
| Details | binding site for residue 1PE F 402 |
| Chain | Residue |
| F | ILE150 |
| F | ARG158 |
| F | GLU241 |
| F | TYR250 |
| F | HIS280 |
| F | THR282 |
| F | TLA401 |
| F | HOH507 |
| F | HOH561 |
| site_id | AE1 |
| Number of Residues | 7 |
| Details | binding site for residue TLA G 401 |
| Chain | Residue |
| G | ARG33 |
| G | HIS34 |
| G | ARG37 |
| G | ILE40 |
| G | ARG101 |
| G | HIS280 |
| G | ASP281 |
| site_id | AE2 |
| Number of Residues | 6 |
| Details | binding site for residue TLA H 401 |
| Chain | Residue |
| H | ARG33 |
| H | HIS34 |
| H | ARG37 |
| H | ARG101 |
| H | HIS280 |
| H | ASP281 |
| site_id | AE3 |
| Number of Residues | 4 |
| Details | binding site for residue 1PE H 402 |
| Chain | Residue |
| H | LYS175 |
| H | GLU178 |
| H | SER232 |
| H | TRP235 |
Functional Information from PROSITE/UniProt
| site_id | PS00616 |
| Number of Residues | 15 |
| Details | HIS_ACID_PHOSPHAT_1 Histidine acid phosphatases phosphohistidine signature. MvfAvdIiRHGdRtP |
| Chain | Residue | Details |
| A | MET25-PRO39 |
