5CB6
Structure of adenosine-5'-phosphosulfate kinase
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000103 | biological_process | sulfate assimilation |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0004020 | molecular_function | adenylylsulfate kinase activity |
| A | 0004781 | molecular_function | sulfate adenylyltransferase (ATP) activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0016301 | molecular_function | kinase activity |
| A | 0016740 | molecular_function | transferase activity |
| A | 0019379 | biological_process | sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin) |
| A | 0070814 | biological_process | hydrogen sulfide biosynthetic process |
| B | 0000103 | biological_process | sulfate assimilation |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0004020 | molecular_function | adenylylsulfate kinase activity |
| B | 0004781 | molecular_function | sulfate adenylyltransferase (ATP) activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0016301 | molecular_function | kinase activity |
| B | 0016740 | molecular_function | transferase activity |
| B | 0019379 | biological_process | sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin) |
| B | 0070814 | biological_process | hydrogen sulfide biosynthetic process |
| C | 0000103 | biological_process | sulfate assimilation |
| C | 0000166 | molecular_function | nucleotide binding |
| C | 0004020 | molecular_function | adenylylsulfate kinase activity |
| C | 0004781 | molecular_function | sulfate adenylyltransferase (ATP) activity |
| C | 0005524 | molecular_function | ATP binding |
| C | 0016301 | molecular_function | kinase activity |
| C | 0016740 | molecular_function | transferase activity |
| C | 0019379 | biological_process | sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin) |
| C | 0070814 | biological_process | hydrogen sulfide biosynthetic process |
| D | 0000103 | biological_process | sulfate assimilation |
| D | 0000166 | molecular_function | nucleotide binding |
| D | 0004020 | molecular_function | adenylylsulfate kinase activity |
| D | 0004781 | molecular_function | sulfate adenylyltransferase (ATP) activity |
| D | 0005524 | molecular_function | ATP binding |
| D | 0016301 | molecular_function | kinase activity |
| D | 0016740 | molecular_function | transferase activity |
| D | 0019379 | biological_process | sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin) |
| D | 0070814 | biological_process | hydrogen sulfide biosynthetic process |
| E | 0000103 | biological_process | sulfate assimilation |
| E | 0000166 | molecular_function | nucleotide binding |
| E | 0004020 | molecular_function | adenylylsulfate kinase activity |
| E | 0004781 | molecular_function | sulfate adenylyltransferase (ATP) activity |
| E | 0005524 | molecular_function | ATP binding |
| E | 0016301 | molecular_function | kinase activity |
| E | 0016740 | molecular_function | transferase activity |
| E | 0019379 | biological_process | sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin) |
| E | 0070814 | biological_process | hydrogen sulfide biosynthetic process |
| F | 0000103 | biological_process | sulfate assimilation |
| F | 0000166 | molecular_function | nucleotide binding |
| F | 0004020 | molecular_function | adenylylsulfate kinase activity |
| F | 0004781 | molecular_function | sulfate adenylyltransferase (ATP) activity |
| F | 0005524 | molecular_function | ATP binding |
| F | 0016301 | molecular_function | kinase activity |
| F | 0016740 | molecular_function | transferase activity |
| F | 0019379 | biological_process | sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin) |
| F | 0070814 | biological_process | hydrogen sulfide biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 17 |
| Details | binding site for residue ADX A 301 |
| Chain | Residue |
| A | GLY41 |
| A | SER86 |
| A | PRO87 |
| A | LEU122 |
| A | GLY133 |
| A | PHE134 |
| A | THR135 |
| A | ANP302 |
| A | HOH419 |
| A | ASP42 |
| A | ARG45 |
| A | PHE54 |
| A | ARG59 |
| A | ASN62 |
| A | ILE63 |
| A | ALA84 |
| A | ILE85 |
| site_id | AC2 |
| Number of Residues | 20 |
| Details | binding site for residue ANP A 302 |
| Chain | Residue |
| A | LEU13 |
| A | SER14 |
| A | GLY15 |
| A | ALA16 |
| A | GLY17 |
| A | LYS18 |
| A | THR19 |
| A | THR20 |
| A | ASP42 |
| A | ARG117 |
| A | LYS120 |
| A | THR153 |
| A | GLU156 |
| A | SER161 |
| A | ADX301 |
| A | MG303 |
| A | NA304 |
| A | HOH402 |
| A | HOH414 |
| A | HOH419 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue MG A 303 |
| Chain | Residue |
| A | THR19 |
| A | ASP40 |
| A | ASP42 |
| A | ANP302 |
| A | HOH402 |
| site_id | AC4 |
| Number of Residues | 8 |
| Details | binding site for residue NA A 304 |
| Chain | Residue |
| A | THR153 |
| A | ASP154 |
| A | GLU156 |
| A | ANP302 |
| B | THR153 |
| B | ASP154 |
| B | GLU156 |
| B | ANP302 |
| site_id | AC5 |
| Number of Residues | 17 |
| Details | binding site for residue ADX B 301 |
| Chain | Residue |
| B | GLY41 |
| B | ASP42 |
| B | ARG45 |
| B | PHE54 |
| B | ARG59 |
| B | ASN62 |
| B | ILE63 |
| B | ALA84 |
| B | ILE85 |
| B | SER86 |
| B | PRO87 |
| B | LEU122 |
| B | GLY133 |
| B | PHE134 |
| B | THR135 |
| B | ANP302 |
| B | HOH401 |
| site_id | AC6 |
| Number of Residues | 20 |
| Details | binding site for residue ANP B 302 |
| Chain | Residue |
| A | GLU156 |
| A | GLU157 |
| A | NA304 |
| B | GLY15 |
| B | GLY17 |
| B | LYS18 |
| B | THR19 |
| B | THR20 |
| B | ASP42 |
| B | ARG117 |
| B | LYS120 |
| B | THR153 |
| B | GLU156 |
| B | GLU157 |
| B | LEU158 |
| B | SER161 |
| B | ADX301 |
| B | MG303 |
| B | HOH401 |
| B | HOH402 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | binding site for residue MG B 303 |
| Chain | Residue |
| B | THR19 |
| B | LYS120 |
| B | ANP302 |
| B | HOH402 |
| site_id | AC8 |
| Number of Residues | 18 |
| Details | binding site for residue ADX C 301 |
| Chain | Residue |
| C | SER86 |
| C | PRO87 |
| C | LYS120 |
| C | LEU122 |
| C | LYS132 |
| C | GLY133 |
| C | PHE134 |
| C | THR135 |
| C | ANP302 |
| C | HOH401 |
| C | SER14 |
| C | ASP42 |
| C | ARG45 |
| C | PHE54 |
| C | ARG59 |
| C | ASN62 |
| C | ALA84 |
| C | ILE85 |
| site_id | AC9 |
| Number of Residues | 18 |
| Details | binding site for residue ANP C 302 |
| Chain | Residue |
| C | LEU13 |
| C | GLY15 |
| C | ALA16 |
| C | GLY17 |
| C | LYS18 |
| C | THR19 |
| C | THR20 |
| C | ASP42 |
| C | ARG117 |
| C | VAL119 |
| C | LYS120 |
| C | THR153 |
| C | GLU156 |
| C | SER161 |
| C | ADX301 |
| C | MG303 |
| C | HOH401 |
| C | HOH404 |
| site_id | AD1 |
| Number of Residues | 4 |
| Details | binding site for residue MG C 303 |
| Chain | Residue |
| C | THR19 |
| C | ASP40 |
| C | ASP42 |
| C | ANP302 |
| site_id | AD2 |
| Number of Residues | 3 |
| Details | binding site for residue CAC C 304 |
| Chain | Residue |
| B | ASP138 |
| C | ASP138 |
| F | ASP138 |
| site_id | AD3 |
| Number of Residues | 17 |
| Details | binding site for residue ADX D 301 |
| Chain | Residue |
| D | GLY41 |
| D | ASP42 |
| D | ARG45 |
| D | PHE54 |
| D | ARG59 |
| D | ASN62 |
| D | ILE63 |
| D | ALA84 |
| D | ILE85 |
| D | SER86 |
| D | PRO87 |
| D | LEU122 |
| D | GLY133 |
| D | PHE134 |
| D | THR135 |
| D | ANP302 |
| D | HOH402 |
| site_id | AD4 |
| Number of Residues | 18 |
| Details | binding site for residue ANP D 302 |
| Chain | Residue |
| D | LEU13 |
| D | SER14 |
| D | GLY15 |
| D | ALA16 |
| D | GLY17 |
| D | LYS18 |
| D | THR19 |
| D | THR20 |
| D | ASP42 |
| D | ARG117 |
| D | VAL119 |
| D | THR153 |
| D | GLU156 |
| D | ADX301 |
| D | MG303 |
| D | HOH402 |
| D | HOH406 |
| D | HOH408 |
| site_id | AD5 |
| Number of Residues | 4 |
| Details | binding site for residue MG D 303 |
| Chain | Residue |
| D | THR19 |
| D | ASP40 |
| D | ASP42 |
| D | ANP302 |
| site_id | AD6 |
| Number of Residues | 3 |
| Details | binding site for residue CAC D 304 |
| Chain | Residue |
| A | ASP138 |
| D | ASP138 |
| E | ASP138 |
| site_id | AD7 |
| Number of Residues | 18 |
| Details | binding site for residue ADX E 301 |
| Chain | Residue |
| E | SER14 |
| E | ASP42 |
| E | ARG45 |
| E | PHE54 |
| E | ARG59 |
| E | ASN62 |
| E | ILE63 |
| E | ALA84 |
| E | ILE85 |
| E | SER86 |
| E | PRO87 |
| E | LYS120 |
| E | LEU122 |
| E | LYS132 |
| E | GLY133 |
| E | PHE134 |
| E | THR135 |
| E | ANP302 |
| site_id | AD8 |
| Number of Residues | 17 |
| Details | binding site for residue ANP E 302 |
| Chain | Residue |
| E | LEU13 |
| E | SER14 |
| E | GLY15 |
| E | ALA16 |
| E | GLY17 |
| E | LYS18 |
| E | THR19 |
| E | THR20 |
| E | ASP42 |
| E | ARG117 |
| E | LYS120 |
| E | THR153 |
| E | GLU156 |
| E | SER161 |
| E | ADX301 |
| E | MG303 |
| E | HOH402 |
| site_id | AD9 |
| Number of Residues | 5 |
| Details | binding site for residue MG E 303 |
| Chain | Residue |
| E | THR19 |
| E | ASP40 |
| E | ASP42 |
| E | ANP302 |
| E | HOH402 |
| site_id | AE1 |
| Number of Residues | 17 |
| Details | binding site for residue ADX F 301 |
| Chain | Residue |
| F | GLY41 |
| F | ASP42 |
| F | ARG45 |
| F | PHE54 |
| F | ARG59 |
| F | ASN62 |
| F | ILE63 |
| F | ALA84 |
| F | ILE85 |
| F | SER86 |
| F | PRO87 |
| F | LYS120 |
| F | LEU122 |
| F | GLY133 |
| F | PHE134 |
| F | THR135 |
| F | ANP302 |
| site_id | AE2 |
| Number of Residues | 21 |
| Details | binding site for residue ANP F 302 |
| Chain | Residue |
| F | LEU13 |
| F | SER14 |
| F | GLY15 |
| F | ALA16 |
| F | GLY17 |
| F | LYS18 |
| F | THR19 |
| F | THR20 |
| F | ASP42 |
| F | ILE85 |
| F | ARG117 |
| F | LYS120 |
| F | THR153 |
| F | GLU156 |
| F | GLU157 |
| F | LEU158 |
| F | SER161 |
| F | ADX301 |
| F | MG303 |
| F | HOH402 |
| F | HOH406 |
| site_id | AE3 |
| Number of Residues | 5 |
| Details | binding site for residue MG F 303 |
| Chain | Residue |
| F | THR19 |
| F | ASP40 |
| F | ASP42 |
| F | ANP302 |
| F | HOH406 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 6 |
| Details | ACT_SITE: Phosphoserine intermediate => ECO:0000250 |
| Chain | Residue | Details |
| A | SER86 | |
| B | SER86 | |
| C | SER86 | |
| D | SER86 | |
| E | SER86 | |
| F | SER86 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 6 |
| Details | BINDING: BINDING => ECO:0000250 |
| Chain | Residue | Details |
| A | GLY12 | |
| B | GLY12 | |
| C | GLY12 | |
| D | GLY12 | |
| E | GLY12 | |
| F | GLY12 |
