5CB6
Structure of adenosine-5'-phosphosulfate kinase
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0000103 | biological_process | sulfate assimilation |
A | 0004020 | molecular_function | adenylylsulfate kinase activity |
A | 0004781 | molecular_function | sulfate adenylyltransferase (ATP) activity |
A | 0005524 | molecular_function | ATP binding |
A | 0010134 | biological_process | sulfate assimilation via adenylyl sulfate reduction |
A | 0016301 | molecular_function | kinase activity |
A | 0016310 | biological_process | phosphorylation |
A | 0019379 | biological_process | sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin) |
A | 0070814 | biological_process | hydrogen sulfide biosynthetic process |
B | 0000103 | biological_process | sulfate assimilation |
B | 0004020 | molecular_function | adenylylsulfate kinase activity |
B | 0004781 | molecular_function | sulfate adenylyltransferase (ATP) activity |
B | 0005524 | molecular_function | ATP binding |
B | 0010134 | biological_process | sulfate assimilation via adenylyl sulfate reduction |
B | 0016301 | molecular_function | kinase activity |
B | 0016310 | biological_process | phosphorylation |
B | 0019379 | biological_process | sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin) |
B | 0070814 | biological_process | hydrogen sulfide biosynthetic process |
C | 0000103 | biological_process | sulfate assimilation |
C | 0004020 | molecular_function | adenylylsulfate kinase activity |
C | 0004781 | molecular_function | sulfate adenylyltransferase (ATP) activity |
C | 0005524 | molecular_function | ATP binding |
C | 0010134 | biological_process | sulfate assimilation via adenylyl sulfate reduction |
C | 0016301 | molecular_function | kinase activity |
C | 0016310 | biological_process | phosphorylation |
C | 0019379 | biological_process | sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin) |
C | 0070814 | biological_process | hydrogen sulfide biosynthetic process |
D | 0000103 | biological_process | sulfate assimilation |
D | 0004020 | molecular_function | adenylylsulfate kinase activity |
D | 0004781 | molecular_function | sulfate adenylyltransferase (ATP) activity |
D | 0005524 | molecular_function | ATP binding |
D | 0010134 | biological_process | sulfate assimilation via adenylyl sulfate reduction |
D | 0016301 | molecular_function | kinase activity |
D | 0016310 | biological_process | phosphorylation |
D | 0019379 | biological_process | sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin) |
D | 0070814 | biological_process | hydrogen sulfide biosynthetic process |
E | 0000103 | biological_process | sulfate assimilation |
E | 0004020 | molecular_function | adenylylsulfate kinase activity |
E | 0004781 | molecular_function | sulfate adenylyltransferase (ATP) activity |
E | 0005524 | molecular_function | ATP binding |
E | 0010134 | biological_process | sulfate assimilation via adenylyl sulfate reduction |
E | 0016301 | molecular_function | kinase activity |
E | 0016310 | biological_process | phosphorylation |
E | 0019379 | biological_process | sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin) |
E | 0070814 | biological_process | hydrogen sulfide biosynthetic process |
F | 0000103 | biological_process | sulfate assimilation |
F | 0004020 | molecular_function | adenylylsulfate kinase activity |
F | 0004781 | molecular_function | sulfate adenylyltransferase (ATP) activity |
F | 0005524 | molecular_function | ATP binding |
F | 0010134 | biological_process | sulfate assimilation via adenylyl sulfate reduction |
F | 0016301 | molecular_function | kinase activity |
F | 0016310 | biological_process | phosphorylation |
F | 0019379 | biological_process | sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin) |
F | 0070814 | biological_process | hydrogen sulfide biosynthetic process |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 17 |
Details | binding site for residue ADX A 301 |
Chain | Residue |
A | GLY41 |
A | SER86 |
A | PRO87 |
A | LEU122 |
A | GLY133 |
A | PHE134 |
A | THR135 |
A | ANP302 |
A | HOH419 |
A | ASP42 |
A | ARG45 |
A | PHE54 |
A | ARG59 |
A | ASN62 |
A | ILE63 |
A | ALA84 |
A | ILE85 |
site_id | AC2 |
Number of Residues | 20 |
Details | binding site for residue ANP A 302 |
Chain | Residue |
A | LEU13 |
A | SER14 |
A | GLY15 |
A | ALA16 |
A | GLY17 |
A | LYS18 |
A | THR19 |
A | THR20 |
A | ASP42 |
A | ARG117 |
A | LYS120 |
A | THR153 |
A | GLU156 |
A | SER161 |
A | ADX301 |
A | MG303 |
A | NA304 |
A | HOH402 |
A | HOH414 |
A | HOH419 |
site_id | AC3 |
Number of Residues | 5 |
Details | binding site for residue MG A 303 |
Chain | Residue |
A | THR19 |
A | ASP40 |
A | ASP42 |
A | ANP302 |
A | HOH402 |
site_id | AC4 |
Number of Residues | 8 |
Details | binding site for residue NA A 304 |
Chain | Residue |
A | THR153 |
A | ASP154 |
A | GLU156 |
A | ANP302 |
B | THR153 |
B | ASP154 |
B | GLU156 |
B | ANP302 |
site_id | AC5 |
Number of Residues | 17 |
Details | binding site for residue ADX B 301 |
Chain | Residue |
B | GLY41 |
B | ASP42 |
B | ARG45 |
B | PHE54 |
B | ARG59 |
B | ASN62 |
B | ILE63 |
B | ALA84 |
B | ILE85 |
B | SER86 |
B | PRO87 |
B | LEU122 |
B | GLY133 |
B | PHE134 |
B | THR135 |
B | ANP302 |
B | HOH401 |
site_id | AC6 |
Number of Residues | 20 |
Details | binding site for residue ANP B 302 |
Chain | Residue |
A | GLU156 |
A | GLU157 |
A | NA304 |
B | GLY15 |
B | GLY17 |
B | LYS18 |
B | THR19 |
B | THR20 |
B | ASP42 |
B | ARG117 |
B | LYS120 |
B | THR153 |
B | GLU156 |
B | GLU157 |
B | LEU158 |
B | SER161 |
B | ADX301 |
B | MG303 |
B | HOH401 |
B | HOH402 |
site_id | AC7 |
Number of Residues | 4 |
Details | binding site for residue MG B 303 |
Chain | Residue |
B | THR19 |
B | LYS120 |
B | ANP302 |
B | HOH402 |
site_id | AC8 |
Number of Residues | 18 |
Details | binding site for residue ADX C 301 |
Chain | Residue |
C | SER86 |
C | PRO87 |
C | LYS120 |
C | LEU122 |
C | LYS132 |
C | GLY133 |
C | PHE134 |
C | THR135 |
C | ANP302 |
C | HOH401 |
C | SER14 |
C | ASP42 |
C | ARG45 |
C | PHE54 |
C | ARG59 |
C | ASN62 |
C | ALA84 |
C | ILE85 |
site_id | AC9 |
Number of Residues | 18 |
Details | binding site for residue ANP C 302 |
Chain | Residue |
C | LEU13 |
C | GLY15 |
C | ALA16 |
C | GLY17 |
C | LYS18 |
C | THR19 |
C | THR20 |
C | ASP42 |
C | ARG117 |
C | VAL119 |
C | LYS120 |
C | THR153 |
C | GLU156 |
C | SER161 |
C | ADX301 |
C | MG303 |
C | HOH401 |
C | HOH404 |
site_id | AD1 |
Number of Residues | 4 |
Details | binding site for residue MG C 303 |
Chain | Residue |
C | THR19 |
C | ASP40 |
C | ASP42 |
C | ANP302 |
site_id | AD2 |
Number of Residues | 3 |
Details | binding site for residue CAC C 304 |
Chain | Residue |
B | ASP138 |
C | ASP138 |
F | ASP138 |
site_id | AD3 |
Number of Residues | 17 |
Details | binding site for residue ADX D 301 |
Chain | Residue |
D | GLY41 |
D | ASP42 |
D | ARG45 |
D | PHE54 |
D | ARG59 |
D | ASN62 |
D | ILE63 |
D | ALA84 |
D | ILE85 |
D | SER86 |
D | PRO87 |
D | LEU122 |
D | GLY133 |
D | PHE134 |
D | THR135 |
D | ANP302 |
D | HOH402 |
site_id | AD4 |
Number of Residues | 18 |
Details | binding site for residue ANP D 302 |
Chain | Residue |
D | LEU13 |
D | SER14 |
D | GLY15 |
D | ALA16 |
D | GLY17 |
D | LYS18 |
D | THR19 |
D | THR20 |
D | ASP42 |
D | ARG117 |
D | VAL119 |
D | THR153 |
D | GLU156 |
D | ADX301 |
D | MG303 |
D | HOH402 |
D | HOH406 |
D | HOH408 |
site_id | AD5 |
Number of Residues | 4 |
Details | binding site for residue MG D 303 |
Chain | Residue |
D | THR19 |
D | ASP40 |
D | ASP42 |
D | ANP302 |
site_id | AD6 |
Number of Residues | 3 |
Details | binding site for residue CAC D 304 |
Chain | Residue |
A | ASP138 |
D | ASP138 |
E | ASP138 |
site_id | AD7 |
Number of Residues | 18 |
Details | binding site for residue ADX E 301 |
Chain | Residue |
E | SER14 |
E | ASP42 |
E | ARG45 |
E | PHE54 |
E | ARG59 |
E | ASN62 |
E | ILE63 |
E | ALA84 |
E | ILE85 |
E | SER86 |
E | PRO87 |
E | LYS120 |
E | LEU122 |
E | LYS132 |
E | GLY133 |
E | PHE134 |
E | THR135 |
E | ANP302 |
site_id | AD8 |
Number of Residues | 17 |
Details | binding site for residue ANP E 302 |
Chain | Residue |
E | LEU13 |
E | SER14 |
E | GLY15 |
E | ALA16 |
E | GLY17 |
E | LYS18 |
E | THR19 |
E | THR20 |
E | ASP42 |
E | ARG117 |
E | LYS120 |
E | THR153 |
E | GLU156 |
E | SER161 |
E | ADX301 |
E | MG303 |
E | HOH402 |
site_id | AD9 |
Number of Residues | 5 |
Details | binding site for residue MG E 303 |
Chain | Residue |
E | THR19 |
E | ASP40 |
E | ASP42 |
E | ANP302 |
E | HOH402 |
site_id | AE1 |
Number of Residues | 17 |
Details | binding site for residue ADX F 301 |
Chain | Residue |
F | GLY41 |
F | ASP42 |
F | ARG45 |
F | PHE54 |
F | ARG59 |
F | ASN62 |
F | ILE63 |
F | ALA84 |
F | ILE85 |
F | SER86 |
F | PRO87 |
F | LYS120 |
F | LEU122 |
F | GLY133 |
F | PHE134 |
F | THR135 |
F | ANP302 |
site_id | AE2 |
Number of Residues | 21 |
Details | binding site for residue ANP F 302 |
Chain | Residue |
F | LEU13 |
F | SER14 |
F | GLY15 |
F | ALA16 |
F | GLY17 |
F | LYS18 |
F | THR19 |
F | THR20 |
F | ASP42 |
F | ILE85 |
F | ARG117 |
F | LYS120 |
F | THR153 |
F | GLU156 |
F | GLU157 |
F | LEU158 |
F | SER161 |
F | ADX301 |
F | MG303 |
F | HOH402 |
F | HOH406 |
site_id | AE3 |
Number of Residues | 5 |
Details | binding site for residue MG F 303 |
Chain | Residue |
F | THR19 |
F | ASP40 |
F | ASP42 |
F | ANP302 |
F | HOH406 |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 6 |
Details | ACT_SITE: Phosphoserine intermediate => ECO:0000250 |
Chain | Residue | Details |
A | SER86 | |
B | SER86 | |
C | SER86 | |
D | SER86 | |
E | SER86 | |
F | SER86 |
site_id | SWS_FT_FI2 |
Number of Residues | 6 |
Details | BINDING: BINDING => ECO:0000250 |
Chain | Residue | Details |
A | GLY12 | |
B | GLY12 | |
C | GLY12 | |
D | GLY12 | |
E | GLY12 | |
F | GLY12 |