5C8G
Crystal Structure Analysis of PP-BRD20 from Tb427tmp complexed with BI-2536
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 11 |
| Details | binding site for residue R78 A 201 |
| Chain | Residue |
| A | TYR41 |
| B | TYR41 |
| B | R78201 |
| A | VAL46 |
| A | VAL51 |
| A | TYR56 |
| A | TYR99 |
| A | ASN100 |
| A | HOH314 |
| A | HOH330 |
| B | GLU40 |
| site_id | AC2 |
| Number of Residues | 13 |
| Details | binding site for residue R78 B 201 |
| Chain | Residue |
| A | GLU40 |
| A | TYR41 |
| A | R78201 |
| B | TYR41 |
| B | VAL46 |
| B | VAL51 |
| B | TYR56 |
| B | TYR99 |
| B | ASN100 |
| B | LEU106 |
| B | HOH312 |
| B | HOH318 |
| B | HOH325 |
Functional Information from PROSITE/UniProt
| site_id | PS00633 |
| Number of Residues | 61 |
| Details | BROMODOMAIN_1 Bromodomain signature. SeyFrepvDalrvgawNYYsvItepMslrtVldyivqggr.Yshveqimndvel.IwkNCerY |
| Chain | Residue | Details |
| A | SER39-TYR99 |
