5C88
Crystal structure of Ard1 N-terminal acetyltransferase from Sulfolobus solfataricus in monoclinic form
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004596 | molecular_function | protein-N-terminal amino-acid acetyltransferase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006474 | biological_process | N-terminal protein amino acid acetylation |
| A | 0008080 | molecular_function | N-acetyltransferase activity |
| A | 0008999 | molecular_function | protein-N-terminal-alanine acetyltransferase activity |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016746 | molecular_function | acyltransferase activity |
| A | 0016747 | molecular_function | acyltransferase activity, transferring groups other than amino-acyl groups |
| A | 0031415 | cellular_component | NatA complex |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0120518 | molecular_function | protein N-terminal-methionine acetyltransferase activity |
| A | 1990189 | molecular_function | protein N-terminal-serine acetyltransferase activity |
| B | 0004596 | molecular_function | protein-N-terminal amino-acid acetyltransferase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0006474 | biological_process | N-terminal protein amino acid acetylation |
| B | 0008080 | molecular_function | N-acetyltransferase activity |
| B | 0008999 | molecular_function | protein-N-terminal-alanine acetyltransferase activity |
| B | 0016740 | molecular_function | transferase activity |
| B | 0016746 | molecular_function | acyltransferase activity |
| B | 0016747 | molecular_function | acyltransferase activity, transferring groups other than amino-acyl groups |
| B | 0031415 | cellular_component | NatA complex |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0120518 | molecular_function | protein N-terminal-methionine acetyltransferase activity |
| B | 1990189 | molecular_function | protein N-terminal-serine acetyltransferase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 19 |
| Details | binding site for residue COA A 300 |
| Chain | Residue |
| A | THR32 |
| A | THR105 |
| A | ASN117 |
| A | ASN132 |
| A | PRO134 |
| A | ALA135 |
| A | ALA137 |
| A | LEU138 |
| A | TYR139 |
| A | HOH402 |
| A | HOH407 |
| A | ILE92 |
| A | VAL94 |
| A | ARG99 |
| A | ARG100 |
| A | LYS101 |
| A | GLY102 |
| A | ILE103 |
| A | ALA104 |
| site_id | AC2 |
| Number of Residues | 19 |
| Details | binding site for residue COA B 300 |
| Chain | Residue |
| B | LEU33 |
| B | ILE92 |
| B | VAL94 |
| B | ARG99 |
| B | ARG100 |
| B | LYS101 |
| B | GLY102 |
| B | ILE103 |
| B | ALA104 |
| B | THR105 |
| B | ASN117 |
| B | GLU127 |
| B | ASN132 |
| B | PRO134 |
| B | ALA135 |
| B | ALA137 |
| B | LEU138 |
| B | TYR139 |
| B | LYS141 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 310 |
| Details | Domain: {"description":"N-acetyltransferase","evidences":[{"source":"PROSITE-ProRule","id":"PRU00532","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"25728374","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4R3L","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"23959863","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4LX9","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 14 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"20419351","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"23959863","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"25728374","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26593285","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2X7B","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4LX9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4R3K","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4R3L","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5C88","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 6 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"20419351","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"23959863","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"25728374","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2X7B","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4LX9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4R3K","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4R3L","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | Site: {"description":"Plays an important role in substrate specificity","evidences":[{"source":"PubMed","id":"25728374","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 4 |
| Details | Site: {"description":"Plays an important role in modulating multiple conformations of loop regions and contributes to protein thermostability","evidences":[{"source":"PubMed","id":"26593285","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
